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About 504 results

ALLMedicine™ Pathophysiology Of Hypertension Center

Research & Reviews  251 results

Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023760
Circulation Research; Harrison DG, Coffman TM et. al.

Apr 1st, 2021 - Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and ...

Impact of hyperleptinemia during placental ischemia-induced hypertension in pregnant rats.
https://doi.org/10.1152/ajpheart.00724.2019
American Journal of Physiology. Heart and Circulatory Phy... Palei AC, Martin HL et. al.

Mar 12th, 2021 - The prevalence of preeclampsia and obesity have increased. While obesity is a major risk factor for preeclampsia, the mechanisms linking these morbidities are poorly understood. Circulating leptin levels increase in proportion to fat mass. Infusio...

Implications of NADPH oxidase 5 in vascular diseases.
https://doi.org/10.1016/j.biocel.2020.105851
The International Journal of Biochemistry & Cell Biology; Marqués J, Cortés A et. al.

Sep 19th, 2020 - Oxidative stress is one of the main mechanisms involved in the pathophysiology of vascular diseases. Among others, oxidative stress promotes endothelial dysfunction, and accelerated ageing and remodelling of vasculature. Lately, NADPH oxidases hav...

Global Plasma Metabolomics to Identify Potential Biomarkers of Blood Pressure Progression.
https://doi.org/10.1161/ATVBAHA.120.314356
Arteriosclerosis, Thrombosis, and Vascular Biology; Lin YT, Salihovic S et. al.

May 27th, 2020 - The pathophysiology of hypertension remains incompletely understood. We investigated associations of circulating metabolites with longitudinal blood pressure (BP) changes in the Prospective Investigation of the Vasculature in Uppsala Seniors cohor...

Blood-brain barrier dysfunction: the undervalued frontier of hypertension.
https://doi.org/10.1038/s41371-020-0352-2 10.1016/j.prp.2014.05.007 10.1111/j.1753-4887.2010.00352.x 10.1038/nm.3407 10.1016/j.semcdb.2015.01.002 10.1152/ajpregu.00103.2010 10.1016/j.resp.2011.05.004 10.1016/j.brainres.2015.03.018 10.1152/ajpheart.00490.2012 10.1016/S0006-8993(00)02954-1 10.1023/B:NERE.0000014828.32200.bd 10.1016/0022-510X(95)00105-B 10.1152/ajpheart.00589.2003 10.3390/ijms20133223 10.1242/jcs.02734 10.1155/2013/297512 10.1161/HYPERTENSIONAHA.113.01743 10.1038/jcbfm.2008.158 10.1111/j.1549-8719.2010.00060.x 10.1016/j.neuroscience.2013.04.023 10.1016/j.neuroscience.2010.09.029 10.1161/HYPERTENSIONAHA.112.195511 10.7326/0003-4819-139-9-200311040-00011 10.1152/physrev.00031.2016 10.1155/2013/164653 10.1161/HYPERTENSIONAHA.115.05333 10.1111/j.1440-1681.2009.05234.x 10.1161/HYPERTENSIONAHA.116.07747 10.1097/NEN.0b013e31826809a6 10.1111/jnc.13905 10.3390/ijms18091965 10.1016/j.pharmthera.2012.07.008 10.1038/s41440-018-0090-9 10.1038/jcbfm.2013.143 10.1016/S0165-0173(00)00043-6 10.1161/HYPERTENSIONAHA.113.01063 10.1016/j.neurobiolaging.2008.08.008 10.1212/01.WNL.0000158283.28251.3C 10.1161/01.STR.27.11.2069 10.1007/s00401-016-1570-0 10.1016/j.lfs.2003.06.014 10.1126/science.6879184 10.1038/nrn1902 10.1073/pnas.96.23.13415 10.1042/CS20130396 10.1016/j.amjhyper.2004.09.004 10.1097/01.hjh.0000354511.14086.f1 10.1161/HYPERTENSIONAHA.109.138586 10.1038/ajh.2010.241 10.1186/s13195-015-0167-5 10.3233/JAD-2011-110347 10.3233/JAD-131694 10.1001/archinternmed.2009.175 10.1136/bmjopen-2013-002881 10.1001/archinte.163.9.1069 10.1016/S1474-4422(10)70250-7 10.1002/gps.1851 10.1016/j.jns.2009.02.335 10.1016/j.brainres.2003.11.061 10.1111/j.1476-5381.1983.tb10506.x 10.1080/00207450490422821 10.3389/fnins.2019.00033 10.1212/WNL.0b013e3182a351d4 10.1001/archneur.63.5.noc60013 10.1016/j.brainres.2005.05.064 10.1254/jphs.SC0060222 10.3389/fphys.2017.01048
Journal of Human Hypertension; Katsi V, Marketou M et. al.

May 19th, 2020 - The blood-brain barrier (BBB) constitutes the complex anatomic and physiologic interface between the intravascular compartment and the central nervous system, and its integrity is paramount for the maintenance of the very sensitive homeostasis of ...

see more →

Clinicaltrials.gov  251 results

Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023760
Circulation Research; Harrison DG, Coffman TM et. al.

Apr 1st, 2021 - Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and ...

Impact of hyperleptinemia during placental ischemia-induced hypertension in pregnant rats.
https://doi.org/10.1152/ajpheart.00724.2019
American Journal of Physiology. Heart and Circulatory Phy... Palei AC, Martin HL et. al.

Mar 12th, 2021 - The prevalence of preeclampsia and obesity have increased. While obesity is a major risk factor for preeclampsia, the mechanisms linking these morbidities are poorly understood. Circulating leptin levels increase in proportion to fat mass. Infusio...

Implications of NADPH oxidase 5 in vascular diseases.
https://doi.org/10.1016/j.biocel.2020.105851
The International Journal of Biochemistry & Cell Biology; Marqués J, Cortés A et. al.

Sep 19th, 2020 - Oxidative stress is one of the main mechanisms involved in the pathophysiology of vascular diseases. Among others, oxidative stress promotes endothelial dysfunction, and accelerated ageing and remodelling of vasculature. Lately, NADPH oxidases hav...

Global Plasma Metabolomics to Identify Potential Biomarkers of Blood Pressure Progression.
https://doi.org/10.1161/ATVBAHA.120.314356
Arteriosclerosis, Thrombosis, and Vascular Biology; Lin YT, Salihovic S et. al.

May 27th, 2020 - The pathophysiology of hypertension remains incompletely understood. We investigated associations of circulating metabolites with longitudinal blood pressure (BP) changes in the Prospective Investigation of the Vasculature in Uppsala Seniors cohor...

Blood-brain barrier dysfunction: the undervalued frontier of hypertension.
https://doi.org/10.1038/s41371-020-0352-2 10.1016/j.prp.2014.05.007 10.1111/j.1753-4887.2010.00352.x 10.1038/nm.3407 10.1016/j.semcdb.2015.01.002 10.1152/ajpregu.00103.2010 10.1016/j.resp.2011.05.004 10.1016/j.brainres.2015.03.018 10.1152/ajpheart.00490.2012 10.1016/S0006-8993(00)02954-1 10.1023/B:NERE.0000014828.32200.bd 10.1016/0022-510X(95)00105-B 10.1152/ajpheart.00589.2003 10.3390/ijms20133223 10.1242/jcs.02734 10.1155/2013/297512 10.1161/HYPERTENSIONAHA.113.01743 10.1038/jcbfm.2008.158 10.1111/j.1549-8719.2010.00060.x 10.1016/j.neuroscience.2013.04.023 10.1016/j.neuroscience.2010.09.029 10.1161/HYPERTENSIONAHA.112.195511 10.7326/0003-4819-139-9-200311040-00011 10.1152/physrev.00031.2016 10.1155/2013/164653 10.1161/HYPERTENSIONAHA.115.05333 10.1111/j.1440-1681.2009.05234.x 10.1161/HYPERTENSIONAHA.116.07747 10.1097/NEN.0b013e31826809a6 10.1111/jnc.13905 10.3390/ijms18091965 10.1016/j.pharmthera.2012.07.008 10.1038/s41440-018-0090-9 10.1038/jcbfm.2013.143 10.1016/S0165-0173(00)00043-6 10.1161/HYPERTENSIONAHA.113.01063 10.1016/j.neurobiolaging.2008.08.008 10.1212/01.WNL.0000158283.28251.3C 10.1161/01.STR.27.11.2069 10.1007/s00401-016-1570-0 10.1016/j.lfs.2003.06.014 10.1126/science.6879184 10.1038/nrn1902 10.1073/pnas.96.23.13415 10.1042/CS20130396 10.1016/j.amjhyper.2004.09.004 10.1097/01.hjh.0000354511.14086.f1 10.1161/HYPERTENSIONAHA.109.138586 10.1038/ajh.2010.241 10.1186/s13195-015-0167-5 10.3233/JAD-2011-110347 10.3233/JAD-131694 10.1001/archinternmed.2009.175 10.1136/bmjopen-2013-002881 10.1001/archinte.163.9.1069 10.1016/S1474-4422(10)70250-7 10.1002/gps.1851 10.1016/j.jns.2009.02.335 10.1016/j.brainres.2003.11.061 10.1111/j.1476-5381.1983.tb10506.x 10.1080/00207450490422821 10.3389/fnins.2019.00033 10.1212/WNL.0b013e3182a351d4 10.1001/archneur.63.5.noc60013 10.1016/j.brainres.2005.05.064 10.1254/jphs.SC0060222 10.3389/fphys.2017.01048
Journal of Human Hypertension; Katsi V, Marketou M et. al.

May 19th, 2020 - The blood-brain barrier (BBB) constitutes the complex anatomic and physiologic interface between the intravascular compartment and the central nervous system, and its integrity is paramount for the maintenance of the very sensitive homeostasis of ...

see more →