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About 4,918 results

ALLMedicine™ Glomerular Filtration Rate (gfr) Center

Research & Reviews  1,726 results

Role of the macula densa sodium glucose cotransporter type 1-nitric oxide synthase 1-tu...
https://doi.org/10.1016/j.kint.2021.10.037
Kidney International; Zhang J, Cai J et. al.

Nov 30th, 2021 - An increase of glomerular filtration rate (GFR) is a common observation in early diabetes and is considered a key risk factor for subsequent kidney injury. However, the mechanisms underlying diabetic hyperfiltration have not been fully clarified. ...

Health-Related Quality of Life according to Renal Function: Results from a Nationwide H...
https://doi.org/10.1159/000518668
Kidney & Blood Pressure Research; Faulhaber L, Herget-Rosenthal S et. al.

Nov 25th, 2021 - Most studies on health-related quality of life (HRQoL) in chronic kidney disease (CKD) focus on patients with end-stage kidney disease although they represent a small proportion of patients with CKD. We aimed to analyze HRQoL according to glomerul...

Metformin Improves Relevant Disease Parameters in an Autosomal Dominant Polycystic Kidn...
https://doi.org/10.1152/ajprenal.00298.2021
American Journal of Physiology. Renal Physiology; Pastor-Soler NM, Li H et. al.

Nov 23rd, 2021 - Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in the PKD1 or PKD2 genes encoding polycystins, presents with progressive development of kidney cysts and eventual end-stage kidney disease (ESKD) with limited treatment opt...

Time to rethink the current paradigm for assessing kidney function in drug development ...
https://doi.org/10.1002/cpt.2489
Clinical Pharmacology and Therapeutics; Sharma A, Sahasrabudhe V et. al.

Nov 21st, 2021 - Chronic kidney disease (CKD) is an important health issue that affects about 9.1% of the world adult population. Serum creatinine is the most commonly used biomarker for assessing kidney function and is utilized in different equations for estimati...

Brain dysfunction in tubular and tubulointerstitial kidney diseases.
https://doi.org/10.1093/ndt/gfab276
Nephrology, Dialysis, Transplantation : Official Publicat... Viggiano D, Bruchfeld A et. al.

Nov 19th, 2021 - Kidney function has two important elements: glomerular filtration and tubular function (secretion and reabsorption). A persistent decrease in glomerular filtration rate (GFR), with or without proteinuria, is diagnostic of chronic kidney disease (C...

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Drugs  7 results see all →

Clinicaltrials.gov  84 results

Renohemodynamic Effects of Combined empagliflOzin and LosARtan
https://clinicaltrials.gov/ct2/show/NCT04238702

Oct 8th, 2021 - Diabetic kidney disease (DKD), characterized by reduced whole-kidney glomerular filtration rate (GFR) and/or urinary protein leakage, is a feared complication of type 2 diabetes (T2DM). With severe consequences such as endstage kidney disease (ESK...

Remission Clinic in Proteinuric Chronic Nephropathies
https://clinicaltrials.gov/ct2/show/NCT02721342

Oct 6th, 2021 - Most chronic kidney diseases have a progressive evolution characterized by the gradual loss of glomerular filtration rate (GFR), electrolytic imbalance, reduced erythropoietin synthesis and activation of vitamin D. On many occasions, the progressi...

Accuracy of Glomerular Filtration Rate (GFR) Estimation Using Creatinine and Cystatin C and Albuminuria
https://clinicaltrials.gov/ct2/show/NCT02433002

Sep 29th, 2021 - The eGFR-C study will assess the accuracy of current and alternative tests of kidney function against a reference test in people with moderate (stage 3) CKD. Participants will be recruited from hospital clinics and General Practitioner (GP) practi...

Belatacept 3 Month Post Transplant Conversion Study
https://clinicaltrials.gov/ct2/show/NCT02213068

Sep 8th, 2021 - Immunosuppressive therapy with the calcineurin inhibitors (CNI) cyclosporine (CsA) and Tacrolimus (Tac), have radically changed the field of organ transplantation. Ironically, although extensively and effectively used for kidney transplantation an...

Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017
https://clinicaltrials.gov/ct2/show/NCT03003468

Aug 23rd, 2021 - OUTLINE: This is a multi-center study. The phase Ib dose escalation will evaluate the combination of pembrolizumab and Imprime PGG for subjects with metastatic non-small cell lung cancer (NSCLC) after progression on first-line platinum-based chemo...

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News  147 results

Fast Five Quiz: Chronic Kidney Disease (CKD) Hyperphosphatemia
https://reference.medscape.com/viewarticle/948765

Apr 26th, 2021 - Hyperphosphatemia or abnormally high serum phosphate levels, has been identified as a key factor associated with cardiovascular complications and increased mortality risk among patients with chronic kidney disease (CKD). Hyperphosphatemia is a lat...

Serious Infections Still Common in Vasculitis
https://www.medpagetoday.com/rheumatology/generalrheumatology/91768

Mar 23rd, 2021 - Serious infections occurred more frequently among patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis who were given induction therapy with cyclophosphamide compared with rituximab (Rituxan), Greek researchers found. Th...

Chronic Kidney Disease Associated With Increased Risk of Renal and Urothelial Cancers
https://www.onclive.com/view/chronic-kidney-disease-associated-with-increased-risk-of-renal-and-urothelial-cancers

Dec 20th, 2020 - Will Lowrance, MD, MPH Assistant Professor, Surgery Huntsman Cancer Institute at the University of Utah Does renal disease increase one’s risk of developing cancer? We know there is a well-studied association between end-stage rena...

Adjuvant Chemotherapy Shows Strong Benefit in Upper Tract Urothelial Carcinoma
https://www.onclive.com/view/adjuvant-chemotherapy-shows-strong-benefit-in-upper-tract-urothelial-carcinoma

Dec 4th, 2020 - Alison J. Birtle, MD, MBBS, MRCP, FRCR Adjuvant platinum-based chemotherapy reduced the risk of disease recurrence or death by 55% in patients with upper tract urothelial carcinoma (UTUC), according to findings from the phase III POUT trial that ...

Diagnosis and Management of Kidney Injury Following HSCT Refined
https://www.onclive.com/view/diagnosis-and-management-of-kidney-injury-following-hsct-refined

Dec 4th, 2020 - Sangeeta R. Hingorani, MD, MPH Kidney complications often occur following successful hematopoietic stem cell transplantation (HSCT) from a myriad of underlying etiologies, according to up-to-date information provided during an educational session...

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Patient Education  3 results see all →