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About 98 results

ALLMedicine™ Light-chain Deposition Disease Center

Research & Reviews  49 results

Immunoglobulin light-chain toxicity in a mouse model of monoclonal immunoglobulin light...
https://doi.org/10.1182/blood.2020005980
Blood Bender S, Ayala MV et. al.

Jun 19th, 2020 - Light chain (LC) deposition disease (LCDD) is a rare disorder characterized by glomerular and peritubular amorphous deposits of a monoclonal immunoglobulin LC, leading to nodular glomerulosclerosis and nephrotic syndrome. We developed a transgenic...

Carfilzomib-induced hemolysis is noticeably common but rarely shows features of thrombo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318150
European Journal of Haematology; Kozlowski P, Kameran Behnam K et. al.

Mar 2nd, 2020 - Hemolysis is a sporadically reported but potentially serious side effect of the proteasome inhibitor carfilzomib. We aimed to investigate the frequency of hemolysis in an unselected cohort. We performed a retrospective, single-center study of the ...

A Case Report of Acute Renal Failure as a Result of Light-Chain-Mediated Acute Tubular ...
https://doi.org/10.7205/MILMED-D-17-00164
Military Medicine; Forster BM, Hinton AP et. al.

Oct 31st, 2017 - We present a 30-year-old combat veteran with an unclear exposure history, with multiple deployments who was later diagnosed with acute renal failure as a result of light-chain deposition disease. Despite a drastic decline in kappa light chains fol...

HD Melphalan and SCT in Patients With IGDD or LCDD
https://clinicaltrials.gov/ct2/show/NCT00681044

Apr 27th, 2017 - OBJECTIVES: To assess the tolerability of high-dose melphalan and autologous stem cell transplantation in patients with immunoglobulin deposition disease or light-chain deposition disease. To determine the hematologic response rate in patients tre...

Diffuse Cystic Lung Diseases: Diagnostic Considerations.
https://doi.org/10.1055/s-0036-1580690
Seminars in Respiratory and Critical Care Medicine; Xu KF, Feng R et. al.

May 27th, 2016 - Diffuse cystic lung disease (DCLD) is a group of heterogeneous diseases that present as diffuse cystic changes in the lung on computed tomography of the chest. Most DCLD diseases are rare, although they might resemble common diseases such as emphy...

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Clinicaltrials.gov  49 results

Immunoglobulin light-chain toxicity in a mouse model of monoclonal immunoglobulin light...
https://doi.org/10.1182/blood.2020005980
Blood Bender S, Ayala MV et. al.

Jun 19th, 2020 - Light chain (LC) deposition disease (LCDD) is a rare disorder characterized by glomerular and peritubular amorphous deposits of a monoclonal immunoglobulin LC, leading to nodular glomerulosclerosis and nephrotic syndrome. We developed a transgenic...

Carfilzomib-induced hemolysis is noticeably common but rarely shows features of thrombo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318150
European Journal of Haematology; Kozlowski P, Kameran Behnam K et. al.

Mar 2nd, 2020 - Hemolysis is a sporadically reported but potentially serious side effect of the proteasome inhibitor carfilzomib. We aimed to investigate the frequency of hemolysis in an unselected cohort. We performed a retrospective, single-center study of the ...

A Case Report of Acute Renal Failure as a Result of Light-Chain-Mediated Acute Tubular ...
https://doi.org/10.7205/MILMED-D-17-00164
Military Medicine; Forster BM, Hinton AP et. al.

Oct 31st, 2017 - We present a 30-year-old combat veteran with an unclear exposure history, with multiple deployments who was later diagnosed with acute renal failure as a result of light-chain deposition disease. Despite a drastic decline in kappa light chains fol...

HD Melphalan and SCT in Patients With IGDD or LCDD
https://clinicaltrials.gov/ct2/show/NCT00681044

Apr 27th, 2017 - OBJECTIVES: To assess the tolerability of high-dose melphalan and autologous stem cell transplantation in patients with immunoglobulin deposition disease or light-chain deposition disease. To determine the hematologic response rate in patients tre...

Diffuse Cystic Lung Diseases: Diagnostic Considerations.
https://doi.org/10.1055/s-0036-1580690
Seminars in Respiratory and Critical Care Medicine; Xu KF, Feng R et. al.

May 27th, 2016 - Diffuse cystic lung disease (DCLD) is a group of heterogeneous diseases that present as diffuse cystic changes in the lung on computed tomography of the chest. Most DCLD diseases are rare, although they might resemble common diseases such as emphy...

see more →