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About 11,158 results

ALLMedicine™ Diabetic Nephropathy Center

Research & Reviews  3,652 results

Prognostic Value of Serum Interleukin-6, NF-κB plus MCP-1 Assay in Patients with Diabet...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232375
Disease Markers; An Z, Qin J et. al.

Jun 28th, 2022 - To assess the prognostic value of serum interleukin-6 (IL-6), nuclear factor-κB (NF-κB), and monocyte chemoattractant protein 1(MCP-1) assay in patients with diabetic nephropathy. From May 2019 to March 2020, 104 patients with diabetic nephropathy...

C1q/tumour necrosis factor-related protein-3 alleviates high-glucose-induced lipid accu...
https://doi.org/10.1016/j.biocel.2022.106247
The International Journal of Biochemistry & Cell Biology; Du C, Zhu Y et. al.

Jun 27th, 2022 - Lipid accumulation and progressive necroinflammation play pivotal roles in the development of diabetic nephropathy. C1q tumour necrosis factor-related protein-3 (CTRP3) is an adipokine with pleiotropic functions in cell proliferation, glucose and ...

Role of olmesartan in ameliorating diabetic nephropathy in rats by targeting the AGE/PK...
https://doi.org/10.1016/j.ejphar.2022.175117
European Journal of Pharmacology; Abo El-Nasr NME, Saleh DO et. al.

Jun 26th, 2022 - Diabetic nephropathy (DN) is one of the most serious consequences of diabetes and the most common reason for end-stage renal disease. The current study was set out to investigate the ability of olmesartan medoxomil (OM) to treat DN by evaluating t...

Increased glucocorticoid metabolism in diabetic kidney disease.
https://doi.org/10.1371/journal.pone.0269920
PloS One; Ackermann D, Vogt B et. al.

Jun 25th, 2022 - Glomerular damage indicated by proteinuria is a main symptom in diabetic nephropathy. Mineralocorticoid receptor (MR) antagonists (MRAs) are beneficial irrespective of aldosterone availability. Thus, we hypothesized an alternatively activated MR t...

Nanodisc delivery of liver X receptor agonist for the treatment of diabetic nephropathy.
https://doi.org/10.1016/j.jconrel.2022.06.029
Journal of Controlled Release : Official Journal of the C... He H, Halseth TA et. al.

Jun 25th, 2022 - Dyslipidemia is recognized to be an important contributor to the progression of diabetic nephropathy (DN), leading to lipoprotein dysregulation, excessive mesangium expansion as well as inflammation in the glomeruli. Thus, dual targeting of abnorm...

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Guidelines  4 results

Clinical practice guidelines for management of hyperglycaemia in adults with diabetic k...
https://doi.org/10.1111/dme.14769
Diabetic Medicine : a Journal of the British Diabetic Ass... Karalliedde J, Winocour P et. al.

Jan 27th, 2022 - A significant percentage of people with diabetes develop chronic kidney disease and diabetes is also a leading cause of end-stage kidney disease (ESKD). The term diabetic kidney disease (DKD) includes both diabetic nephropathy (DN) and diabetes me...

Validation of the 2007 kidney disease outcomes quality initiative clinical practice gui...
https://doi.org/10.1016/j.diabres.2018.11.008
Diabetes Research and Clinical Practice; Liu XM, Dong ZY et. al.

Nov 26th, 2018 - Diabetes mellitus (DM) has overtaken infection and immunological factors as the most common cause of end-stage renal disease. The 2007 Kidney Disease Outcomes Quality Initiative (KDOQI) guideline is a widely accepted guideline for the clinical dia...

Management of adults with diabetes on the haemodialysis unit: summary of guidance from ...
https://doi.org/10.1111/dme.13676
Diabetic Medicine : a Journal of the British Diabetic Ass... Frankel AH, Kazempour-Ardebili S et. al.

Aug 29th, 2018 - Diabetic nephropathy remains the principal cause of end-stage renal failure in the UK and its prevalence is set to increase. People with diabetes and end-stage renal failure on maintenance haemodialysis are highly vulnerable, with complex comorbid...

Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis...
https://doi.org/10.1002/dmrr.1239
Diabetes/metabolism Research and Reviews; Spallone V, Ziegler D et. al.

Jun 23rd, 2011 - The Cardiovascular Autonomic Neuropathy (CAN) Subcommittee of the Toronto Consensus Panel on Diabetic Neuropathy worked to update CAN guidelines, with regard to epidemiology, clinical impact, diagnosis, usefulness of CAN testing, and management. C...

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Drugs  292 results see all →

Clinicaltrials.gov  331 results

Niclosamide Role in Diabetic Nephropathy
https://clinicaltrials.gov/ct2/show/NCT04317430

Jun 21st, 2022 - This study is randomized, controlled, parallel, prospective clinical study will be conducted on 60 patients diagnosed with type 2 diabetes mellitus at least five years ago. Patients will be recruited from Tanta University Hospital, Tanta, Egypt. A...

Huangqi Guizhi Wuwu Decoction in CKD Stage 2-4 Diabetic Nephropathy
https://clinicaltrials.gov/ct2/show/NCT05418465

Jun 14th, 2022 - The incidence rate of chronic kidney disease is 10.8% in China. The incidence rate of diabetic nephropathy has increased year by year, and now it has become the first cause of uremia. Therefore, the treatment of diabetic nephropathy can delay the ...

Value of Uric Acid as Early Predictor of Lupus Nephritis
https://clinicaltrials.gov/ct2/show/NCT05402735

Jun 2nd, 2022 - Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disorder identified by the production of autoantibodies and immune complex deposition [1]. It presents with a variety of unpredictable flares of disease activity and irreversible organ da...

To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy
https://clinicaltrials.gov/ct2/show/NCT05047471

May 27th, 2022 - Among the various complications of diabetes mellitus, DKD is considered as a major threat and is one of the manifestations of diabetic microangiopathy. it is one of the main causes of death for patients with T2DM. Albuminuria is the earliest manif...

Telmisartan Promotes the Differentiation of Monocytes Into Macrophages M2 in Diabetic Nephropathy?
https://clinicaltrials.gov/ct2/show/NCT02768948

May 19th, 2022 - The severity of the diabetic nephropathy is proportional to proteinuria rate and degree of renal interstitial fibrosis. Despite many treatments available today, diabetic nephropathy is responsible for a quarter of cases of end-stage renal disease ...

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News  180 results

Pruritus and pitting edema
https://www.mdedge.com/type-2-diabetes-challenge-center/article/255400/type-2-diabetes/pruritus-and-pitting-edema

Jun 13th, 2022 - The 2020 Kidney Disease Improving Global Outcomes (KDIGO) diabetes management in CKD guideline states that most patients with diabetic nephropathy and an eGFR ≥ 30 mL/min/1. 73 m 2benefit from treatment with both metformin and a sodium-glucose cotr.

Fast Five Quiz: Risk for Diabetic Nephropathy Progression
https://reference.medscape.com/viewarticle/969127

Mar 22nd, 2022 - Diabetic kidney disease traditionally has been referred to as diabetic nephropathy. The terms are used interchangeably, but the increased use of "diabetic kidney disease" has been prompted by a new classification system for chronic kidney disease ...

Higher BMI Increases Risk of Diabetic Kidney Disease
https://www.medscape.com/viewarticle/969334

Feb 28th, 2022 - Higher body mass index (BMI) has been linked to an increased risk for diabetic nephropathy, new research finds. The study of nearly 4000 East Asian individuals with type 2 diabetes used genetic analysis to show that higher BMI was associated with ...

Lupin Recalls Irbesartan and Hydrochlorothiazide/Irbesartan Tablets
https://www.medscape.com/viewarticle/960937

Oct 14th, 2021 - Lupin Pharmaceuticals is recalling all batches of irbesartan tablets USP 75 mg, 150 mg, and 300 mg and irbesartan and hydrochlorothiazide (HCTZ) tablets USP 150 mg/12.5 mg and 300 mg/12.5 mg because of the potential presence of the N-nitrosoirbesa...

Cardiovascular Disease a Continuing Challenge in Type 1 Diabetes
https://www.medscape.com/viewarticle/957027

Aug 23rd, 2021 - Despite a significant decline in cardiovascular disease risk for people with type 1 diabetes over time, the risk remains higher than that of the general population, new data from Finland show. Findings from the study of nearly 12,000 Finnish peopl...

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Patient Education  4 results see all →