About 285 results

ALLMedicine™ HIV-associated Nephropathy Center

Research & Reviews  104 results

Prevalence and risk factors of chronic kidney disease in an HIV positive Mexican cohort.
BMC Nephrology; Valdivia-Cerda V, Alvarez-Zavala M et. al.

Sep 25th, 2021 - HIV subjects have several kidney pathologies, like HIV-associated nephropathy or antiretroviral therapy injury, among others. The global prevalence of Chronic Kidney Disease (CKD) is 8-16%; however, in HIV subjects, the prevalence varies between g...

Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors hum...
Disease Models & Mechanisms; McCarthy GM, Blasio A et. al.

Aug 6th, 2021 - People of recent sub-Saharan African ancestry develop kidney failure much more frequently than other groups. A large fraction of this disparity is due to two coding sequence variants in the APOL1 gene. Inheriting two copies of these APOL1 risk var...

Regional and Racial Disparities in HIV-Related Kidney Disease.
Contributions to Nephrology; Sinclair M, Wyatt CM

Aug 4th, 2021 - Clinical Background and Epidemiology: Worldwide, an estimated 38 million people are living with HIV infection. The classic kidney disease of HIV infection, commonly known as HIV-associated nephropathy, is a collapsing form of focal segmental glome...

Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice.
Disease Models & Mechanisms; Das JR, Jerebtsova M et. al.

Jul 27th, 2021 - People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the...

HIV-Associated Nephropathy

Jul 1st, 2021 - HIV-associated nephropathy is characterized by clinical findings similar to those of focal segmental glomerulosclerosis and often biopsy features of collapsing glomerulopathy (a variant of focal segmental glomerulosclerosis).

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Guidelines  2 results

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Impr...
Kidney International; Swanepoel CR, Atta MG et. al.

Feb 6th, 2018 - HIV-positive individuals are at increased risk for kidney disease, including HIV-associated nephropathy, noncollapsing focal segmental glomerulosclerosis, immune-complex kidney disease, and comorbid kidney disease, as well as kidney injury resulti...

Antiretroviral treatment of adult HIV infection: 2008 recommendations of the Internatio...
JAMA Hammer SM, Eron JJ et. al.

Aug 5th, 2008 - The availability of new antiretroviral drugs and formulations, including drugs in new classes, and recent data on treatment choices for antiretroviral-naive and -experienced patients warrant an update of the International AIDS Society-USA guidelin...

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Clinicaltrials.gov  2 results

Observational Study of HIV+ Deceased Donor Transplant for HIV+ Recipients

Jun 16th, 2021 - This is an observational study designed to evaluate safety and outcomes of solid organ transplantation in HIV+ recipients of HIV+ deceased donor organs. This study will evaluate overall survival and graft survival compared to transplantation with ...

HIV-to-HIV Transplant at MGH

May 11th, 2021 - This is an observational study designed to evaluate safety and outcomes of solid organ transplantation in HIV+ recipients of HIV+ deceased donors. This study will evaluate overall survival and graft survival compared to transplantation with an HIV...

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News  6 results

HIV Treatment Guidelines for Adults and Adolescents Updated

Apr 10th, 2012 - April 10, 2012 — The Department of Health and Human Services (DHHS) Panel on Antiretroviral Guidelines for Adults and Adolescents has updated recommendations for clinical practitioners caring for patients with HIV infection in the United States, b...

Genetic Basis for End-Stage Renal Disease in Type 2 Diabetes

Nov 4th, 2010 - Genetic Variants of the Protein Kinase C-Beta 1 Gene in the Development of End-Stage Renal Disease Patients With Type 2 Diabetes Ma RC, Tam CH, Wang Y, et al JAMA. 2010;304:881-889 Study Background According to observational data, populations of p...

DHHS Issues New Guidelines for the Use of Antiretroviral Therapy

Dec 2nd, 2009 - December 2, 2009 — The DHHS Panel on Antiretroviral Guidelines for Adults and Adolescents (a working group of the Office of AIDS Research Advisory Council) has issued new guidelines December 1 for the use of antiretroviral agents in HIV-1-infected...

HIV-Associated Kidney Disease

Jun 2nd, 2009 - This Viewpoint synthesizes a recent review of HIV-related kidney disease by 6 experts on the topic. Kidney Disease in Patients With HIV Infection and AIDS Winston J, Deray G, Hawkins T, Szczech L, Wyatt C, Young B Clin Infect Dis. 2008;47:1449-145...

Influence of Hepatitis C Virus Co-Infection and Hepatitis C Virus Treatment on Risk of Chronic Kidney Disease in HIV-Positive Persons

Discussion This large study of almost 15 000 individuals with a median follow-up of approaching 7 years and with known anti-HCV and HCV-RNA status has found no reduction in CKD among those with cured HCV infection following treatment for HCV. To d...

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