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About 123 results

ALLMedicine™ Primary Systemic Amyloidosis Center

Research & Reviews  40 results

Visual Dermatology: Primary Systemic Amyloidosis.
https://doi.org/10.1177/12034754211064314
Journal of Cutaneous Medicine and Surgery; Zhang Y, Feng L

Dec 9th, 2021 - Visual Dermatology: Primary Systemic Amyloidosis.|2021|Zhang Y,Feng L,|

Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL)
https://clinicaltrials.gov/ct2/show/NCT00981708

Apr 30th, 2021 - Primary systemic amyloidosis (AL) is a plasma cell dyscrasia where amyloid fibrils are formed by monoclonal immunoglobulin light chains and deposit in various organs causing tissue damage and dysfunction. It is a rare disease with an incidence of ...

Asymptomatic Hemorrhagic Lesions in an Anemic Woman
https://www.mdedge.com/dermatology/article/238565/rare-diseases/asymptomatic-hemorrhagic-lesions-anemic-woman
Kavina Patel, BS, Zachary Gillooly, MD et. al.

Apr 13th, 2021 - The Diagnosis: Bullous Amyloidosis A punch biopsy from the left temple showed deposits of amorphous eosinophilic material at the tips of dermal papillae and in the papillary dermis with hemorrhage present (Figure 1). A diagnosis of amyloidosis was.

Spontaneous bilateral peri-orbital purpura: an important clinical sign of primary syste...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021580
BMJ Case Reports; Beatty PE, Killion L et. al.

Apr 3rd, 2021 - A 69-year-old woman presented with an 18-month history of recurrent bruising of the eyelids. She was otherwise asymptomatic and systems review was unremarkable. On examination, she had peri-orbital purpura and waxy papules at the inner canthus of ...

Peripheral Nervous System Involvement.
https://doi.org/10.1016/j.hoc.2020.07.004
Hematology/oncology Clinics of North America; Thaisetthawatkul P, Dyck PJB

Oct 26th, 2020 - Peripheral nervous system involvement in primary systemic amyloidosis is another important organ involvement in the spectrum of this disease entity. Early recognition may lead to an earlier diagnosis and treatment with improvement in prognosis.

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Clinicaltrials.gov  5 results

Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL)
https://clinicaltrials.gov/ct2/show/NCT00981708

Apr 30th, 2021 - Primary systemic amyloidosis (AL) is a plasma cell dyscrasia where amyloid fibrils are formed by monoclonal immunoglobulin light chains and deposit in various organs causing tissue damage and dysfunction. It is a rare disease with an incidence of ...

Lendexal in Patients With Primary Systemic Amyloidosis (AL) Newly Diagnosed
https://clinicaltrials.gov/ct2/show/NCT01194791

Apr 25th, 2017 - It is a multicenter, single arm treatment, phase II study of the combination in one treatment arm with Lenalidomide, Cyclophosphamide and Dexamethasone. Subjects who qualify for participation will receive lenalidomide plus dexamethasone and cyclop...

Study of Bortezomib +HSCT in Primary Systemic Amyloidosis (AL)
https://clinicaltrials.gov/ct2/show/NCT01273844

Apr 7th, 2017 - Patients will receive two 21-day cycles of induction therapy with vel / dex regimen. Bortezomib 1.3mg/m2 on days 1, 4, 8 and 11 will be given by intravenous bolus injection while Dexamethasone 40 mg/d will be taken orally on days 1-4. After two cy...

S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT00002849

Mar 6th, 2015 - OBJECTIVES: Evaluate M protein and organ dysfunction responses and overall and progression-free survival in patients with primary systemic amyloidosis treated with dexamethasone/interferon alfa. Identify prognostic factors that may relate to respo...

Efficacy of CC-5013 (Revlimid or Lenalidomide) in Patients With Primary Systemic Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT00166413

May 6th, 2011 - Patients with primary systemic amyloidosis will be treated with CC-5013 (lenalidomide; Revlimid) as a single agent for 3 months. If their disease worsens or does not improve during that time frame dexamethasone will be added to the treatment program.

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News  4 results

Seeking a New Path for AL Amyloidosis
https://www.onclive.com/view/seeking-a-new-path-for-al-amyloidosis

Oct 6th, 2021 - Giada Bianchi, MD Associate Director of the Brigham and Women’s Hospital/Dana-Farber Cancer Institute’s Amyloidosis Program Attending Physician, the Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Instructor in Medicine...

Asymptomatic Hemorrhagic Lesions in an Anemic Woman
https://www.mdedge.com/dermatology/article/238565/rare-diseases/asymptomatic-hemorrhagic-lesions-anemic-woman
Kavina Patel, BS, Zachary Gillooly, MD et. al.

Apr 13th, 2021 - The Diagnosis: Bullous Amyloidosis A punch biopsy from the left temple showed deposits of amorphous eosinophilic material at the tips of dermal papillae and in the papillary dermis with hemorrhage present (Figure 1). A diagnosis of amyloidosis was.

Nontender Nodules on the Lower Lip
https://www.mdedge.com/dermatology/article/86232/dermatopathology/nontender-nodules-lower-lip
Jeffrey R. Smith, MD, MPH, Megan N. Moody, MD, MPH

Aug 6th, 2014 - The Diagnosis: Primary Systemic Amyloidosis Our patient presented with multiple firm waxy nodules on the mucosal surface of the lower lip. Excision biopsy showed thickening of blood vessel walls with abundant amorphous material that was consistent.

Primary Cutaneous Nodular Amyloidosis: Case Report and Review of the Literature
https://www.mdedge.com/dermatology/article/67858/primary-cutaneous-nodular-amyloidosis-case-report-and-review-literature
Schwendiman MN, Beachkofsky TM et. al.

Primary cutaneous nodular amyloidosis (PCNA) is a rare form of primary cutaneous amyloidosis. It presents as waxy yellow-red nodules that are located preferentially on the lower extremities, face, scalp, and genitals.

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