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Multi-center observational study on the adherence, quality of life, and adverse events in lung cancer patients treated with tyrosine kinase inhibitors
Journal of Oncology Pharmacy Practice; Rosentreter J

Aug 2nd, 2020 - Cancer patients tend to prefer oral instead of parenteral chemotherapy. To date, there is little evidence on the medication adherence in cancer patients. We investigated medication adherence to tyrosine kinase inhibitors in patients suffering from non-small cell lung cancer.

Hepatitis B Virus Screening and Management for Patients With Cancer Prior to Therapy: ASCO Provisional Clinical Opinion Update
Journal of Clinical Oncology; Hwang JP

Jul 26th, 2020 - This Provisional Clinical Opinion update presents a clinically pragmatic approach to hepatitis B virus (HBV) screening and management.

FDA approves brexucabtagene autoleucel for relapsed or refractory mantle cell lymphoma

Jul 23rd, 2020 - The Food and Drug Administration granted accelerated approval to brexucabtagene autoleucel (TECARTUS, Kite, a Gilead Company), a CD19-directed genetically modified autologous T cell immunotherapy, for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL).

Survey finds 40% of U.S. LGBTQ youth considered suicide in past year

Jul 15th, 2020 - NEW YORK (Reuters) - Forty percent of young LGBTQ people in the United States say they have seriously considered suicide over the past 12 months, according to a survey released on Wednesday, while the figure climbs to more than 50% for transgender and non-binary youth surveyed. FILE PHOTO: A rainbow flag waves in the wind at the Stonewall National Monument outside the Stonewall Inn, site of the...

Moderna Phase 1 results show coronavirus vaccine safe, induces immune response

Jul 15th, 2020 - CHICAGO (Reuters) - Moderna Inc’s (MRNA.O) experimental vaccine for COVID-19 showed it was safe and provoked immune responses in all 45 healthy volunteers in an ongoing early-stage study, U.S. researchers reported on Tuesday. Volunteers who got two doses of the vaccine had high levels of virus-killing antibodies that exceeded the average levels seen in people who had recovered from COVID-19, th...

Living near gas flaring sites may increase risk of preterm birth, study shows

Jul 15th, 2020 - WASHINGTON (Reuters) - Women living near oil and gas production sites where natural gas is flared may be at a higher risk of giving birth preterm, a team of California researchers reported on Wednesday. FILE PHOTO: A flare burns excess natural gas in the Permian Basin in Loving County, Texas, U.S. November 23, 2019. REUTERS/Angus Mordant/File Photo Analysis of more than 23,000 birth records fro...

U.S. government agrees to buy Becton's COVID-19 testing devices

Jul 15th, 2020 - (Reuters) - The U.S. government will buy Becton, Dickinson and Co’s COVID-19 testing devices and kits, the company said on Wednesday, as it ramps up its testing for the virus that has been spreading at an alarming rate. The U.S. Department of Health and Human Services has agreed to buy 2,000 of its BD Veritor Plus Systems and 750,000 of its SARS-CoV-2 antigen test kits, the company said. Accord...

UN warns of dangerous drop in vaccinations during COVID pandemic

Jul 15th, 2020 - FILE PHOTO: A doctor wearing a protective face shield uses an infrared thermometer to measure the temperature of a child at his mobile health clinic, after his clinic and its adjoining areas were declared a micro-containment zone, after authorities eased lockdown restrictions that were imposed to slow the spread of the coronavirus disease (COVID-19), in Ahmedabad, India, June 15, 2020. REUTERS/...

Roche gene testing key to $1.7 billion deal for Blueprint cancer drug

Jul 14th, 2020 - ZURICH (Reuters) - Roche (ROG.S) has struck a $1.7 billion cancer drug pact with Blueprint Medicines (BPMC.O), it said on Tuesday, as advances in genetic testing for rare mutations drive lucrative deals for expensive treatments. FILE PHOTO: Workers clean the windows of a building of Roche in Rotkreuz May 27, 2020. REUTERS/Arnd Wiegmann/File Photo The Swiss drugmaker will pay $675 million in cas...

Study predicts surge in HIV, TB and malaria deaths amid COVID-19 pandemic

Jul 13th, 2020 - LONDON (Reuters) - Deaths from HIV, tuberculosis and malaria could surge in poor and middle-income countries as already weak health systems grapple with severe disruptions from the COVID-19 pandemic, according to a predictive study published on Monday. Over the next five years, deaths from the three diseases could rise by as much as 10%, 20% and 36% respectively - putting the mortality impact o...

Kazakhstan to extend coronavirus lockdown by two weeks

Jul 13th, 2020 - ALMATY (Reuters) - Kazakhstan will extend its second coronavirus lockdown by two weeks until the end of July and again offer financial aid to those who have lost their source of income, President Kassym-Jomart Tokayev said on Monday. Kazakhstan, which reported a major resurgence in COVID-19 and often-related pneumonia cases after lifting restrictions in May, entered a second, albeit less string...

Germany extends fencing along Polish border to keep out swine fever

Jul 13th, 2020 - HAMBURG (Reuters) - Fencing along the German-Polish border is being extended in stepped-up efforts to prevent African swine fever being spread to Germany by wild boars, German authorities said on Monday. The 62-km (38-mile) fence adds to some 240 km of barriers put up along the frontier - over half its total length - by German states earlier this year after the ASF disease was found in wild boa...

WHO's Ryan says pneumonia in Kazakhstan 'on our radar'

Jul 13th, 2020 - GENEVA (Reuters) - Mike Ryan, head of the World Health Organization’s emergencies programme, said on Friday that an outbreak of pneumonia in Kazakhstan, reported to be highly lethal, was “certainly on our radar”. But he also said it was possible it might be COVID-19. “The upward trajectory of COVID-19 in the country would suggest that many of these cases are in fact undiagnosed cases of COVID-1...

Response to: ‘COVID-19 in patients with rheumatic diseases: what is the real mortality risk?’ by Marques et al
Annals of Rheumatic Diseases; D'Silva DM

Jul 12th, 2020 - We appreciate the comments by Marques et al in response to our manuscript. Their description of a cohort of patients with rheumatic disease and COVID-19 is another important contribution to the literature during this quickly evolving pandemic. In this report of 130 patients with rheumatic diseases, the authors estimated a mortality rate of 9.2%, higher than the 4.7% mortality rate reported in t...

India's Biocon secures approval to use drug on coronavirus patients

Jul 11th, 2020 - FILE PHOTO: India's Biocon Ltd Chairman and Managing Director Kiran Mazumdar-Shaw speaks during the Forbes Global CEO Conference in Kuala Lumpur September 13, 2011. REUTERS/Bazuki Muhammad/File Photo NEW DELHI (Reuters) - India’s Biocon Ltd has received regulatory approval for its drug Itolizumab to be used on coronavirus infected patients suffering from moderate to severe respiratory distress,...

WHO official cites AIDS as guide to addressing coronavirus pandemic

Jul 10th, 2020 - FILE PHOTO: WHO Health Emergencies Programme head Michael Ryan attends a news conference organized by Geneva Association of United Nations Correspondents (ACANU) amid the COVID-19 outbreak, caused by the novel coronavirus, at the WHO headquarters in Geneva, Switzerland July 3, 2020. Fabrice Coffrini/Pool via REUTERS (Reuters) - Healthcare systems worldwide need to upgrade to control disease tra...

Fauci says likely some degree of aerosol transmission of new coronavirus

Jul 10th, 2020 - (Reuters) - The new coronavirus is likely spreading through the air to some degree, the top U.S. infectious disease official said on Friday, one day after the World Health Organization urged further studies on the ways the virus is transmitted. “Still some question about aerosol but likely some degree of aerosol,” Anthony Fauci, the head of the U.S. National Institute of Allergy and Infectious ...

Tuberculosis vaccine may be limiting COVID-19 deaths; dormitory screening urged

Jul 10th, 2020 - (Reuters) - The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus. FILE PHOTO: The ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV), which was identified as the cause of an outbreak of respiratory illness first detected in Wuhan, Ch...

FDA unclear if benefits of GSK multiple myeloma drug outweigh risks

Jul 10th, 2020 - LONDON (Reuters) - The U.S. Food and Drug Administration said on Friday it was unclear whether the benefits of GlaxoSmithKline’s experimental treatment for a common form of blood cancer outweigh the risks ahead of a review of a side-effect which affects the eyes. FILE PHOTO: General view outside GlaxoSmithKline (GSK) headquarters in Brentford, following the outbreak of the coronavirus disease (...