About 22,588 results
Cutaneous Pemphigus Vegetans Co-occurring With Oral Pemphigus Vulgaris
Jennifer W. Lee, MD, Stefan G. Vanderweil, MD et. al.

Jan 17th, 2020 - To the Editor: A 74-year-old man with a history of colon cancer and no history of sexually transmitted diseases presented with tender, moist, vegetating, and verrucous plaques localized to the inguinal creases and behind the scrotum of 3 weeks’ duration (Figure 1). The patient recently had taken lisinopril prescribed by his primary care physician for a couple of years for hypertension before sw.

Kidneys From Donors With AKI Safe for Transplant, But Often Unused

Jan 13th, 2020 - Transplanted kidneys from deceased donors who had acute kidney injury (AKI) show no differences in short- or long-term failure, or graft rejection, compared with those that came from donors without AKI, in some of the strongest evidence on the issue to date. Yet many organs from donors with AKI still go unused in the United States, according to the study authors. "We estimate there may hundreds...

Gout rates reduced with SGLT2 inhibitors
Heidi Splete

Jan 13th, 2020 - The incidence of gout was approximately 40% lower in diabetes patients who were prescribed sodium-glucose cotransporter 2 inhibitors (SGLT2) than it was in those who were prescribed glucagonlike peptide–1 receptor (GLP-1) agonists in a population-based new-user cohort study. Hyperuricemia is a known cause of gout and common in type 2 diabetes patients.

Pharmacist BP telemonitoring cut cardiovascular events, turned profit
Bruce Jancin

Jan 13th, 2020 - PHILADELPHIA – A home blood pressure telemonitoring program featuring pharmacist management of patients with uncontrolled hypertension reduced cardiovascular events by half and was cost saving over the course of 5 years, even though the intervention ended after year 1, Karen L. Margolis, MD, reported at the American Heart Association scientific sessions.

New Renal-Imaging Modalities Help Diagnose Congenital Anomalies Early

Jan 8th, 2020 - NEW YORK (Reuters Health) - State-of-the-art renal imaging facilitates the early diagnosis of congenital anomalies of the kidney and urinary tract (CAKUT), according to a review. CAKUT make up 20% to 30% of all anomalies identified in the prenatal period and occur in up to 60% of children with chronic kidney disease in the postnatal period. CAKUT often present with urinary tract dilation (UTD)....

New hypertension performance measures boost 130/80 mm Hg target
Mitchel L. Zoler

Jan 6th, 2020 - PHILADELPHIA – The American Heart Association and American College of Cardiology took a big step toward facilitating widespread U. S.

In COPD, Carbon Dioxide Is Often Overlooked

Jan 5th, 2020 - When it comes to outcome targets for chronic obstructive pulmonary disease (COPD), carbon dioxide is often overlooked. Most pulmonary and internal medicine physicians know oxygen therapy can improve mortality for patients with COPD and hypoxia. Anecdotally, they'll be quick to tell you that hypoxia leads to exercise intolerance and pulmonary arterial hypertension, and supplemental oxygen improv...

Kidney Disease Up as Prescribing Errors Exacerbate the Problem

Jan 5th, 2020 - The prevalence of chronic kidney disease (CKD), as well as its major risk factors, has steadily increased in recent years, yet measures to identify, treat, and avoid medications that can exacerbate the disease remain low, new research indicates. These latest findings reveal "a burgeoning number of patients with CKD and its major risk factors. Rates of identification and use of kidney protective...

Mediterranean Diet Repeats as Best Overall of 2020

Jan 1st, 2020 - For the third year in a row, the Mediterranean diet has been named the best diet overall in the U.S. News & World Report annual rankings. In 2018, the Mediterranean diet shared top honors with the DASH (Dietary Approaches to Stop Hypertension) diet. Both focus on fruits, vegetables, and whole grains. The ketogenic diet, one of the most popular, again fared well in the annual survey, but only in...

High-dose Vitamin D Supplementation Appears to Be Safe

Dec 23rd, 2019 - NEW YORK (Reuters Health) - Vitamin D supplementation in doses up to 10,000 IU/day appears to be safe and well tolerated, though higher doses increase the risk of hypercalciuria and mild hypercalcemia, according to a secondary analysis from the Calgary Vitamin D randomized controlled trial. "Supplementation with vitamin D 4,000 IU/day or more is not necessary for most community-dwelling adults ...

Acute Kidney Injury After PCI Adds $10,000 to Hospital Costs

Dec 22nd, 2019 - Contrast-induced acute kidney injury (AKI) is a common complication of percutaneous coronary intervention (PCI) and, when it occurs, increases hospital stay by 3.6 days and adds an extra $10,000 in costs, researchers estimate. The findings are based on health insurance data from more than 1.4 million patients who had PCI at 518 hospitals in the United States in roughly the past 10 years. The re...

Do PPIs Increase the Risk for Renal Damage or Mortality?

Dec 22nd, 2019 - Proton pump inhibitors (PPIs) are ubiquitous in patient medication lists, whether prescribed alone or as part of a cocktail to treat many upper gastrointestinal disorders. A variety of adverse renal effects have been associated with chronic PPI use, and these drugs have been blamed for episodes of acute kidney injury and progression of chronic kidney disease. It is no surprise then that some re...

Tivozanib Prolongs PFS in Refractory Kidney Cancer

Dec 19th, 2019 - NEW YORK (Reuters Health) - In patients with refractory renal cell carcinoma (RCC), third- or fourth-line tivozanib improved progression-free survival and was better tolerated than sorafenib, a pivotal study shows. "The study adds a novel option for patients with previously treated RCC," Dr. Brian Rini of Cleveland Clinic in Ohio told Reuters Health by email. "If FDA approved, this would repres...

Long hours at a desk job linked to hidden high blood pressure

Dec 19th, 2019 - (Reuters Health) - Working long hours behind a desk might raise the risk of undiagnosed high blood pressure, or hypertension, even when readings in a doctor’s office are normal, a new study suggests. FILE PHOTO: A man has his blood pressure checked at the Remote Area Medical Clinic in Wise, Virginia, U.S., July 22, 2017. REUTERS/Joshua Roberts In an analysis of data from more than 3,500 white c...

RCC: Tivozanib beats sorafenib in later lines
Will Pass

Dec 19th, 2019 - For third- or fourth-line treatment of metastatic renal cell carcinoma, the vascular epidermal growth factor receptor (VEGFR) tyrosine kinase inhibitor tivozanib may offer better progression-free survival than sorafenib, another VEGFR inhibitor, based on results from the TIVO-3 trial. Susan London/MDedge News Dr.

Many UK Children With Kidney Disease May Be Prescribed Nephrotoxic Drugs

Dec 17th, 2019 - NEW YORK (Reuters Health) - Primary care practices in the UK seem to be prescribing nephrotoxic drugs to many children with chronic kidney disease (CKD), a retrospective analysis reveals. "CKD is rare in children," Dr. Michael Zappitelli of the Toronto Hospital for Sick Children told Reuters Health by email. "However, children have many years ahead of them; therefore, anything which can slow th...

Low RAAS inhibitor dosing linked to MACE risk
Bianca Nogrady

Dec 17th, 2019 - Suboptimal dosing of renin-angiotensin-aldosterone system (RAAS) inhibitors to reduce the risk of hyperkalemia could increase the risk of major adverse cardiac events (MACE) and all-cause mortality in patients with chronic kidney disease (CKD) or heart failure. HYWARDS/Thinkstock Researchers reported the outcomes of an observational study that explored the real-world associations between RAAS i.

SZC passes extension test for hyperkalemia
Jim Kling

Dec 14th, 2019 - Treatment with sodium zirconium cyclosilicate (SZC) led to lasting improvement of hyperkalemia, according to results from an 11-month open-label extension study of the HARMONIZE randomized clinical trial. SZC selectively binds potassium ions in the colon, reducing absorption and promoting excretion.

The Week That Wasn't: Cell Phone Injuries, Hypertension Mouthwash, Reversing Dementia

Dec 12th, 2019 - Recent medical news included headlines about injuries by cell phone, hypertension-fighting mouthwash made from bees, and dementia reversed. But you didn't see any of those stories on Medscape Medical News. Here's why. Injuries by Cell Phone The number of cell phone–related injuries to the head and neck increased steadily between 1998 and 2017, according to a recent study published in JAMA Otola...