About 11,923 results

ALLMedicine™ Alzheimer Disease Center

Research & Reviews  4,297 results

Type 2 Diabetes, Glycemic Control, and Their Association With Dementia and Its Major Su...
Diabetes Care; Celis-Morales CA, Franzén S et. al.

Jan 26th, 2022 - Type 2 diabetes has been associated with high dementia risk. However, the links to different dementia subtypes is unclear. We examined to what extent type 2 diabetes is associated with dementia subtypes and whether such associations differed by gl...

Normal-pressure hydrocephalus: A rare cause of reversible dementia.
JAAPA : Official Journal of the American Academy of Physi... Liang K, Chebrolu P

Jan 26th, 2022 - Normal-pressure hydrocephalus (NPH) is characterized by the clinical triad of dementia, gait instability, and urinary incontinence. The estimated annual incidence is 1.8 cases in 100,000 persons, making NPH a rare diagnosis and uncommon cause of d...

Association of Nursing Home Organizational Culture and Staff Perspectives With Variabil...
JAMA Internal Medicine; Palan Lopez R, Hendricksen M et. al.

Jan 25th, 2022 - Regional, facility, and racial and ethnic variability in intensity of care provided to nursing home residents with advanced dementia is well documented but poorly understood. To assess the factors associated with facility and regional variation in...

Alzheimer disease and neuroplasticity.
Handbook of Clinical Neurology; Koch G, Spampinato D

Jan 18th, 2022 - Alzheimer's disease (AD) is considered the most harmful form of dementia in the elderly population. At present, there are no effective treatments and this is likely due to the incomplete understanding of the pathophysiology. Recent data indicate t...

Sharper in the morning: Cognitive time of day effects revealed with high-frequency smar...
Journal of Clinical and Experimental Neuropsychology; Wilks H, Aschenbrenner AJ et. al.

Jan 18th, 2022 - Decades of research has established a shift from an "eveningness" preference to a "morningness" preference with increasing age. Accordingly, older adults typically have better cognition in morning hours compared to evening hours. We present the fi...

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Guidelines  6 results

ACR Appropriateness Criteria® Dementia.
Journal of the American College of Radiology : JACR; , Moonis G et. al.

May 7th, 2020 - Degenerative disease of the central nervous system is a growing public health concern. The primary role of neuroimaging in the workup of patients with probable or possible Alzheimer disease has typically been to exclude other significant intracran...

Falls Risk and Alzheimer Disease: A Patient Guide.
Archives of Physical Medicine and Rehabilitation; Kahya M, Sood P et. al.

Mar 3rd, 2020 - Falls Risk and Alzheimer Disease: A Patient Guide.|2020|Kahya M,Sood P,Devos H,Krishnan S,Hirsch MA,|

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.
Alzheimer Disease and Associated Disorders; Sachdev P, Kalaria R et. al.

Mar 19th, 2014 - Several sets of diagnostic criteria have been published for vascular dementia since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical reexamination. Participants at a special symposium of the International Soc...

Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cogn...
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Johnson KA, Minoshima S et. al.

Jul 3rd, 2013 - Amyloid PET imaging is a novel diagnostic test that can detect in living humans one of the two defining pathologic lesions of Alzheimer disease, amyloid-β deposition in the brain. The Amyloid Imaging Task Force of the Alzheimer's Association and S...

Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the ...
Genetics in Medicine : Official Journal of the American C... Goldman JS, Hahn SE et. al.

May 18th, 2011 - Alzheimer disease is the most common cause of dementia. It occurs worldwide and affects all ethnic groups. The incidence of Alzheimer disease is increasing due, in part, to increased life expectancy and the aging baby boomer generation. The averag...

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Drugs  5 results see all →

Clinicaltrials.gov  65 results

Efficacy of Nano-PSO in Parkinson's Disease.

Dec 2nd, 2021 - A new fatty acid extracted from the pomegranate showed unexpectedly beneficial properties after nanotechnological processing. Encouraging effects of the new substance called nano-PSO led to design the present investigation. Indeed, the substance i...

Resilience and Brain Health of Older Adults During the COVID-19 Pandemic (MEDEX-2)

Nov 17th, 2021 - This project capitalizes on a natural experiment imposed by the COVID-19 pandemic in conjunction with an extensive set of cognitive, emotional, biological, and neuroimaging variables already collected at multiple time points in older adults partic...

Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study

Sep 8th, 2021 - The present project aims at exploring different components of Self-consciousness or 'the Self', such as autobiographical memory, self-concept and subjective sense of Self, in dementia with Lewy Bodies (DLB) compared to Alzheimer's disease and to n...

Evaluating the Relationship Between Tau PET Imaging and CSF Biomarkers of AD (Alzheimer Disease) in Humans

Jun 10th, 2021 - The purpose of this research study is to evaluate a new radioactive compound used in positron emission tomography (PET) scans in identifying tau tangles (a certain protein that might be associated with Alzheimer's disease) in the brain, and if the...

Colon Cancer Surgery in the Aged; Postoperative Outcome, Functional Recovery and Survival.

May 19th, 2021 - 9 Finnish hospitals including three university hospitals participate in the study. The data is collected from the hospitals using a specially designed and secure web application (RedCap). The preoperative patients' data include comorbidities, clin...

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News  396 results

Implications of FDA Approval of Alzheimer Drug May Extend to Novel Anticancer Therapies

Jan 10th, 2022 - It is difficult to know where exactly to begin this commentary regarding the FDA approval to permit commer-cial sales of the Alzheimer disease drug aducanumab-avwa (Aduhelm). There are so many disturbing features of this story, with likely more to...

Cataract Surgery Seen Protective Against Dementia

Dec 10th, 2021 - Older patients who undergo cataract surgery may reduce their risk of developing dementia by roughly 30%, new research shows. Dr Cecilia Lee Although previous studies have linked sensory impairment to dementia, whether correcting vision problems in...

Verubecestat Promising for Glioblastoma

Dec 3rd, 2021 - NEW YORK (Reuters Health) - Verubecestat, a beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) inhibitor originally developed to treat Alzheimer's disease, showed promise against glioblastoma in a preclinical study. "Because BACE1 inhib...

Biden Seeks to Return Califf as FDA Chief

Nov 12th, 2021 - President Joe Biden on Friday said he will nominate Robert Califf, MD, to return as the top US regulator of drugs and medical devices, selecting a cardiologist with extensive experience in clinical trials. Califf served as the commissioner of the ...

Sleep Time 'Sweet Spot' to Slow Cognitive Decline Identified?

Oct 26th, 2021 - Sleeping too much or too little can lead to cognitive decline over time, but new research suggests there could be a sleep time "sweet spot" that stabilizes cognitive function. In a longitudinal study, investigators found older adults who slept les...

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