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About 3,438 results

ALLMedicine™ Dementia With Lewy Bodies Center

Research & Reviews  1,277 results

Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson's ...
https://doi.org/10.3233/JPD-212849
Journal of Parkinson's Disease; Lawson RA, Richardson SJ et. al.

Nov 30th, 2021 - Delirium is a serious acute neuropsychiatric condition associated with altered attention and arousal. To evaluate simple bedside tests for attention and arousal to detect delirium in those with and without Parkinson's disease (PD) and dementia. Pa...

Clinical Laboratory Evaluation of Chronic Autonomic Failure
https://clinicaltrials.gov/ct2/show/NCT03648905

Nov 30th, 2021 - Objective: In dysautonomias, altered functions of one or more components of the autonomic nervous system adversely affect health. A subset of dysautonomias consists of chronic autonomic failure (CAF) syndromes. A key sign of CAF is orthostatic hyp...

Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia wi...
https://doi.org/10.3233/JAD-215285
Journal of Alzheimer's Disease : JAD; Reale M, Carrarini C et. al.

Nov 23rd, 2021 - Central nervous system disruption of cholinergic (ACh) signaling, which plays a major role in cognitive processes, is well documented in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). The expression of muscarinic ACh receptors type ...

Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Pa...
https://doi.org/10.1001/jamaneurol.2021.4222
JAMA Neurology; Gonzalez MC, Ashton NJ et. al.

Nov 23rd, 2021 - Plasma phosphorylated tau (p-tau) has proven to be an accurate biomarker for Alzheimer disease (AD) pathologic characteristics, offering a less expensive and less invasive alternative to cerebrospinal fluid (CSF) and positron emission tomography b...

Weight loss in Alzheimer's disease, vascular dementia and dementia with Lewy bodies: Im...
https://doi.org/10.1002/gps.5659
International Journal of Geriatric Psychiatry; Soysal P, Tan SG et. al.

Nov 23rd, 2021 - Loss of weight is associated with cognitive decline as well as several adverse outcomes in dementia. The aim of this study was to assess whether weight loss is associated with mortality and hospitalization in dementia subtypes. A cohort of 11,607 ...

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Drugs  5 results see all →

Clinicaltrials.gov  24 results

Clinical Laboratory Evaluation of Chronic Autonomic Failure
https://clinicaltrials.gov/ct2/show/NCT03648905

Nov 30th, 2021 - Objective: In dysautonomias, altered functions of one or more components of the autonomic nervous system adversely affect health. A subset of dysautonomias consists of chronic autonomic failure (CAF) syndromes. A key sign of CAF is orthostatic hyp...

The PACE-DLB Study
https://clinicaltrials.gov/ct2/show/NCT04829656

Nov 23rd, 2021 - Dementia with Lewy bodies (DLB) is part of Lewy body dementia, the 2nd-most-common degenerative dementia in the U.S. It is also one of the Alzheimer's disease-related dementias (ADRDs). Evidence-based models of end-of-life care for ADRDs are insuf...

ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies
https://clinicaltrials.gov/ct2/show/NCT04831281

Nov 1st, 2021 - The study is designed to evaluate the safety and treatment effects of ATH-1017 in subjects with Parkinson's Disease Dementia or Dementia with Lewy Bodies, with a randomized, double-blind, placebo-controlled, parallel-arm treatment duration of 26 w...

Prazosin and CSF Biomarkers in mTBI
https://clinicaltrials.gov/ct2/show/NCT03221751

Sep 24th, 2021 - A majority of neurodegenerative dementing disorders, including Alzheimer's disease, (AD), dementia with Lewy bodies (DLB) and chronic traumatic encephalopathy (CTE), now appear to be caused by the accumulation and aggregation of proteins that caus...

Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study
https://clinicaltrials.gov/ct2/show/NCT04616287

Sep 8th, 2021 - The present project aims at exploring different components of Self-consciousness or 'the Self', such as autobiographical memory, self-concept and subjective sense of Self, in dementia with Lewy Bodies (DLB) compared to Alzheimer's disease and to n...

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News  65 results

Positive Topline Results for Novel Parkinson's Treatment
https://www.medscape.com/viewarticle/958356

Sep 8th, 2021 - Topline results from a study that tested two lead structurally targeted allosteric regulator (STAR) compounds ― GT-02287 and GT-02329 ― are promising for the treatment of Gaucher disease (GD) and GBA1-associated Parkinson's disease (PD). "The topl...

Staying on Pimavanserin Cut Dementia-Related Psychosis Relapse
https://www.medpagetoday.com/psychiatry/dementia/93689

Jul 21st, 2021 - The atypical antipsychotic pimavanserin (Nuplazid) reduced the risk of dementia-related psychosis relapse, according to the phase III HARMONY trial. Following an open-label treatment phase to determine treatment response, a double-blind phase foun...

Dementia Made Simple
https://www.medscape.com/viewarticle/951395

Jun 14th, 2021 - This transcript has been edited for clarity. Matthew F. Watto, MD: Welcome back to The Curbsiders. I'm Dr Matthew Watto, here with my good friend, Dr Paul Williams. We are going to talk about "dementia made simple" from a great conversation we had...

Mild Cognitive Impairment with Lewy Bodies or Alzheimer’s Disease and Risk of Progression to Dementia
https://www.medscape.com/viewarticle/949921

Apr 26th, 2021 - Takeaway Patients with mild cognitive impairment (MCI) and clinical characteristics of dementia with Lewy bodies (DLB) had a worse prognosis than MCI-Alzheimer’s disease (MCI-AD), with an increased annual risk of transition from MCI to dementia. M...

Tau PET Tracer Distinguishes Between Alzheimer, Non-Alzheimer Disorders
https://www.medscape.com/viewarticle/930516

May 15th, 2020 - NEW YORK (Reuters Health) - The tau PET tracer R0948 F 18 ((18F)R0948) accurately differentiates Alzheimer disease from non-Alzheimer neurodegenerative disorders, researchers report. Tau-selective PET tracers allow in vivo visualization of tau pat...

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Patient Education  4 results see all →