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About 20,805 results

ALLMedicine™ Mild Cognitive Impairment Center

Research & Reviews  7,274 results

Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
https://clinicaltrials.gov/ct2/show/NCT03574207

Dec 3rd, 2021 - The investigators propose a pilot study of the potential for non-invasive transcranial magnetic stimulation (TMS) to improve memory in healthy adults (young and old) and to treat memory deficits in older adults with amnestic mild cognitive impairm...

Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-...
https://doi.org/10.1212/WNL.0000000000013017
Neurology Angevaare MJ, Vonk JMJ et. al.

Dec 3rd, 2021 - To investigate socio-demographic and medical predictors of incident mild cognitive impairment (MCI) and subsequent course of MCI at follow-up, including sustained MCI diagnosis, classification as cognitively normal, and progression to dementia. Wi...

Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than...
https://doi.org/10.1002/alz.12508
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Frank B, Ally M et. al.

Dec 3rd, 2021 - We examined the ability of plasma hyperphosphorylated tau (p-tau)181 to detect cognitive impairment due to Alzheimer's disease (AD) independently and in combination with plasma total tau (t-tau) and neurofilament light (NfL). Plasma samples were a...

The prevalence of mild cognitive impairment in Latin America and the Caribbean: a syste...
https://doi.org/10.1080/13607863.2021.2003297
Aging & Mental Health; Ribeiro FS, Teixeira-Santos AC et. al.

Dec 1st, 2021 - The population of Latin America and Caribbean (LAC) is ageing rapidly, presenting the highest prevalence rates of dementia in the world. Mild cognitive impairment (MCI) is an intermediate condition between normal ageing, Alzheimer's disease, and r...

Use of robots to encourage social engagement between older adults.
https://doi.org/10.1016/j.gerinurse.2021.11.008
Geriatric Nursing (New York, N.Y.); Lin YC, Fan J et. al.

Dec 1st, 2021 - We designed a robotic architecture system within a commercially available socially assistive robot to engage pairs of older adults in multimodal activities over 3 weeks for 6 sessions. The study took place in two assisted living facilities. Seven ...

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Guidelines  5 results

Screening for Cognitive Impairment in Older Adults: US Preventive Services Task Force R...
https://doi.org/10.1001/jama.2020.0435
JAMA , Owens DK et. al.

Feb 26th, 2020 - Dementia (also known as major neurocognitive disorder) is defined by a significant decline in 1 or more cognitive domains that interferes with a person's independence in daily activities. Dementia affects an estimated 2.4 to 5.5 million individual...

Treatment of dementia and mild cognitive impairment with or without cerebrovascular dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488894
CNS Neuroscience & Therapeutics; Kandiah N, Ong PA et. al.

Jan 17th, 2019 - The Ginkgo biloba special extract, EGb 761® has been widely used in the treatment of neuropsychiatric disorders, including Alzheimer's disease (AD). To guide clinical practice in the Asian region, the Asian Clinical Expert Group on Neurocognitive ...

Practice guideline update summary: Mild cognitive impairment: Report of the Guideline D...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772157
Neurology Petersen RC, Lopez O et. al.

Dec 29th, 2017 - To update the 2001 American Academy of Neurology (AAN) guideline on mild cognitive impairment (MCI). The guideline panel systematically reviewed MCI prevalence, prognosis, and treatment articles according to AAN evidence classification criteria, a...

Screening for cognitive impairment in older adults: U.S. Preventive Services Task Force...
https://doi.org/10.7326/M14-0496
Annals of Internal Medicine; Moyer VA,

Mar 26th, 2014 - Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for dementia. The USPSTF reviewed the evidence on the benefits, harms, and sensitivity and specificity of screening instruments for cognitive impairment in...

Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cogn...
https://doi.org/10.1016/j.jalz.2013.06.001
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Johnson KA, Minoshima S et. al.

Jul 3rd, 2013 - Amyloid PET imaging is a novel diagnostic test that can detect in living humans one of the two defining pathologic lesions of Alzheimer disease, amyloid-β deposition in the brain. The Amyloid Imaging Task Force of the Alzheimer's Association and S...

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Drugs  2 results see all →

Clinicaltrials.gov  278 results

Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
https://clinicaltrials.gov/ct2/show/NCT03574207

Dec 3rd, 2021 - The investigators propose a pilot study of the potential for non-invasive transcranial magnetic stimulation (TMS) to improve memory in healthy adults (young and old) and to treat memory deficits in older adults with amnestic mild cognitive impairm...

Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Mild Cognitive Impairment (tDCS)
https://clinicaltrials.gov/ct2/show/NCT03191916

Nov 30th, 2021 - Parkinson's disease (PD) is the second most common neurodegenerative disease (after Alzheimer's disease) and affects approximately one million people in the United States. Mild Cognitive Impairment (MCI) is very common even in early stages of PD. ...

A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)
https://clinicaltrials.gov/ct2/show/NCT04867616

Nov 29th, 2021 - The purpose of the study is to investigate the effect of bepranemab versus (vs) placebo on the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) up to Week 80 in study participants with prodromal or mild Alzheimer's Disease (AD).

Water-based Activity to Enhance Recall in Veterans
https://clinicaltrials.gov/ct2/show/NCT04296565

Nov 17th, 2021 - The primary research question of the proposed study is this: Is a water-based exercise plus cognitive training intervention efficacious in improving cognitive outcomes for Veterans with Mild Cognitive Impairment (MCI)? The investigators address th...

Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol
https://clinicaltrials.gov/ct2/show/NCT02854033

Nov 17th, 2021 - The overall goal of ADNI3 is to determine the relationships among the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of Alzheimer's disease (AD), as the pathology evolves from normal aging th...

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News  758 results

Premenopausal bilateral oophorectomy linked to later cognitive impairment
https://www.mdedge.com/obgyn/article/249029/menopause/premenopausal-bilateral-oophorectomy-linked-later-cognitive
Kate Johnson

Nov 23rd, 2021 - Women whose ovaries were surgically removed before the age of 46 had a higher risk of mild cognitive impairment (MCI) around 30 years later, compared with those who did not undergo bilateral oophorectomy, according to a population-based linkage st.

Brain Inflammation Seen in Four of 10 Alzheimer's Aducanumab Patients
https://www.medpagetoday.com/neurology/alzheimersdisease/95801

Nov 22nd, 2021 - Brain inflammation known as amyloid-related imaging abnormalities (ARIA) occurred in about 40% of people with early Alzheimer's disease in the two phase III studies of aducanumab (Aduhelm), a secondary analysis of trial data showed. In an integrat...

Type 2 Diabetes Worsens Parkinson's Disease
https://www.medscape.com/viewarticle/962501

Nov 8th, 2021 - Key Takeaways Among adults with recently diagnosed Parkinson's disease, those with concomitant type 2 diabetes had at study entry more severe motor symptoms and a greater overall burden of nonmotor symptoms compared with patients without type 2 di...

Sleep Time 'Sweet Spot' to Slow Cognitive Decline Identified?
https://www.medscape.com/viewarticle/961589

Oct 26th, 2021 - Sleeping too much or too little can lead to cognitive decline over time, but new research suggests there could be a sleep time "sweet spot" that stabilizes cognitive function. In a longitudinal study, investigators found older adults who slept les...

Sleep Apnea Has Many Faces
https://www.medscape.com/viewarticle/961271

Oct 20th, 2021 - I recently saw a 62-year-old patient who had been struggling in her job at a law firm. She had been one of the top paralegals for over a decade, but recently had received a poor job performance. She told me she was forgetting things and was worrie...

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Patient Education  5 results see all →