ALLMedicine™ Absence Seizures Center

Feb 26th, 2023 - Using the gamma-butyrolactone (GBL) model of absence seizures in Long-Evans rats, this study investigated if gamma (30-160 Hz) activity were cross-frequency modulated by the 2-6 Hz slow-wave discharges induced by GBL in the limbic system. We hypot...

Feb 8th, 2023 - Sunflower Syndrome (also referred to as Self-induced Photosensitive Epilepsy) is a rare epileptic disorder characterized by a distinctive seizure that manifests itself in a highly stereotyped physical behavior. Seizure types associated with Sunflo...

Feb 4th, 2023 - Myoclonus can be epileptic or nonepileptic. Epileptic myoclonus has been defined in clinical, neurophysiological, and neuroanatomical terms. Juvenile myoclonic epilepsy (JME) is typically considered to be an adolescent-onset idiopathic generalized...

Feb 3rd, 2023 - Spike-and-wave discharges (SWDs), generated by the cortico-thalamo-cortical (CTC) network, are pathological, large amplitude oscillations and the hallmark of absence seizures (ASs). SWDs begin in a cortical initiation network in both humans and an...

Jan 26th, 2023 - Practice Essentials Phenytoin is a commonly prescribed anticonvulsant used to treat most types of seizure disorders and status epilepticus. It is not effective for treatment of absence seizures and it is no longer considered appropriate for the ma...

Feb 8th, 2023 - Sunflower Syndrome (also referred to as Self-induced Photosensitive Epilepsy) is a rare epileptic disorder characterized by a distinctive seizure that manifests itself in a highly stereotyped physical behavior. Seizure types associated with Sunflo...

Sep 21st, 2022 - Epileptic seizures arise from neuronal defects that often alter the capacity of the brain to process sensory information. During absence seizures, a frequent epileptic syndrome in children, the normal conscious and perceptual processes are tempora...

Sep 8th, 2022 - This is a Phase 2a, open-label study consisting of a screening period of up to 4 weeks and a 4-dose-titration treatment period to a dose of up to 10 mg twice daily (BID) of CX-8998, followed by a 1-week safety follow-up period after the last dose ...

Jul 5th, 2022 - Seizures can be difficult to detect outside of the hospital even with careful observation by a caregiver. EEG is the best method that we have to detect seizures- but it is uncomfortable for long term use outside of the hospital. The goal of this s...

May 24th, 2021 - This is a Pilot study, open-label study consisting of a screening period of up to 4 weeks, a 4-week dose-titration treatment period to dose of up to 20 mg/kg/day BID of CBD (Epidiolex), and a 30 day safety follow-up period following the last dose ...

Dec 12th, 2022 - NASHVILLE, TENN. – Researchers have reported for the first time a process that may explain the progression of absence seizures that seems to provoke dysregulation of the insulating layer surrounding nerve fibers, perpetuating a cycle of increasing...

Dec 9th, 2022 - NASHVILLE, TENN. – Researchers have reported for the first time a process that may explain the progression of absence seizures that seems to provoke dysregulation of the insulating layer surrounding nerve fibers, perpetuating a cycle of increasing.

Feb 2nd, 2022 - The Skill Checkup series provides a quick, case-style interactive quiz highlighting key guidelines- and evidence-based information to inform clinical practice. A 20-year-old woman has a history of tuberous sclerosis, symptomatic generalized epilep...

Mar 23rd, 2020 - My Take on Deprescribing Antiepileptic Drugs Records from the patient's workup 5 years earlier and the last clinic note from neurology, dated 2 years earlier, are available. At that time, the neurologist recommended continuing his treatment. Befor...

Apr 1st, 2019 - A 60-year-old man is admitted for respiratory failure following a massive myocardial infarction. He develops ventilator-associated pneumonia and is treated with cefepime and vancomycin.