About 1,670 results

ALLMedicine™ Absence Seizures Center

Research & Reviews  295 results

Prolongation of absence seizures and changes in serotonergic and dopaminergic neurotran...
Pharmacology, Biochemistry, and Behavior; Tugba EK, Medine GIO et. al.

Jan 3rd, 2022 - Basal ganglia structures play an important role in the pathophysiology of absence epilepsy, known as remote control of absence seizures. We examined the role of the nigrostriatal dopaminergic pathway in absence epilepsy through behavioral and elec...

The orexin system: a potential player in the pathophysiology of absence epilepsy?
Current Neuropharmacology; Celli R, Luijtelaar GV

Dec 17th, 2021 - Absence epilepsy is characterized by the presence of spike-and-wave discharges (SWDs) at the EEG generated within the cortico-thalamo-cortical circuit. The molecular mechanisms involved in the pathophysiology of absence epilepsy are only partially...

Absence seizures during sleep in childhood absence epilepsy: A sign of drug resistance?
Brain & Development; Chen J, Liu P et. al.

Dec 14th, 2021 - Childhood absence epilepsy (CAE) is a common pediatric epilepsy syndrome. It is characterized by typical absence seizures and a highly recognizable electroencephalography (EEG) pattern. But little is known about absence seizures during sleep. A 7-...

Electroclinical features and long-term therapeutic response in patients with typical ab...
Epileptic Disorders : International Epilepsy Journal With... Vlachou M, Skrimpas GA et. al.

Dec 4th, 2021 - To characterize in detail the electroclinical features of typical absence seizures and elucidate whether EEG or semiology features, alone or in combination, can predict long-term therapeutic outcome. We analysed video-EEG recordings from 213 typic...

Transcranial Direct Current Stimulation Reduces Anxiety, Depression and Plasmatic Corti...
Neuroscience Gouveia FV, Germann J et. al.

Nov 15th, 2021 - Affective disorders (i.e. anxiety and depression) are commonly observed in patients with epilepsy and induce seizure aggravation. Animal models of epilepsy that exhibit affective disorder features are essential in developing new neuromodulatory tr...

see more →

Drugs  348 results see all →

Clinicaltrials.gov  6 results

Mutual Interactions Between Absence Epilepsy Seizures and the Integration of Sensory Stimuli

Sep 8th, 2021 - Epileptic seizures arise from neuronal defects that often alter the capacity of the brain to process sensory information. During absence seizures, a frequent epileptic syndrome in children, the normal conscious and perceptual processes are tempora...

Epidiolex in Typical Absence Seizures

May 24th, 2021 - This is a Pilot study, open-label study consisting of a screening period of up to 4 weeks, a 4-week dose-titration treatment period to dose of up to 20 mg/kg/day BID of CBD (Epidiolex), and a 30 day safety follow-up period following the last dose ...

A Phase 2 Study of CX-8998 in Adolescents and Adults With Idiopathic Generalized Epilepsy With Absence Seizures

Apr 3rd, 2020 - This is a Phase 2a, open-label study consisting of a screening period of up to 4 weeks and a 4-dose-titration treatment period to a dose of up to 10 mg twice daily (BID) of CX-8998, followed by a 1-week safety follow-up period after the last dose ...

Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures

Aug 21st, 2018 - This study, conducted in children with typical or atypical "absence" epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures without the need for a...

Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study

Jun 29th, 2016 - Participant recruitment and informed consent Study participants were recruited via advertisement at the pediatric outpatient department, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. The study procedures were described...

see more →

News  16 results

Off to College: Safe to Stop His Antiepileptic Drug?

Mar 23rd, 2020 - My Take on Deprescribing Antiepileptic Drugs Records from the patient's workup 5 years earlier and the last clinic note from neurology, dated 2 years earlier, are available. At that time, the neurologist recommended continuing his treatment. Befor...

Unusual effects of common antibiotics
Maria Elena Ruiz, MD, Glenn W. Wortmann, MD

Apr 1st, 2019 - A 60-year-old man is admitted for respiratory failure following a massive myocardial infarction. He develops ventilator-associated pneumonia and is treated with cefepime and vancomycin.

How Often Are Staring Spells Seizures?

Jan 4th, 2019 - Approximately 50% were referred by an emergency department, 48% by a primary care physician, and 2% by an urgent care clinic. Of the 62 cases that turned out to be nonepileptic events, about 61% were referred by primary care physicians.

Understanding and Managing Sunflower Syndrome

Apr 16th, 2018 - Sunflower syndrome, a type of reflex seizure usually accompanied by eyelid myoclonia, can be managed with valproate or polypharmacy suggests a recent study of affected patients managed by the Department of Neurology, Division of Child Neurology, S.

Epilepsy: Osmosis Study Video

Jul 21st, 2017 - What is Epilepsy? Epilepsy is a condition characterized by recurrent and unpredictable seizures. Seizures are characterized by groups of neurons being activated simultaneously, leading to both outward symptoms like muscle jerking and convulsions, ...

see more →

Patient Education  3 results see all →