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About 10,135 results

ALLMedicine™ Antiepileptic Drugs Center

Research & Reviews  3,190 results

Innovative treatments for epilepsy: Venom peptides, cannabinoids, and neurostimulation.
https://doi.org/10.1002/jnr.25114
Journal of Neuroscience Research; Lima LS, Loyola V et. al.

Aug 9th, 2022 - Antiepileptic drugs have been successfully treating epilepsy and providing individuals sustained seizure freedom. However, about 30% of the patients with epilepsy present drug resistance, which means they are not responsive to the pharmacological ...

COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/rito...
https://doi.org/10.1007/s00228-022-03370-7
European Journal of Clinical Pharmacology; Yalcin N, Allegaert K

Aug 6th, 2022 - Management and dose adjustment are a major concern for clinicians in the absence of specific clinical outcome data for patients on antiepileptic drugs (AEDs), in the event of short-term (5 days) nirmatrelvir/ritonavir co-exposure. Therefore, in th...

Felbamate add-on therapy for drug-resistant focal epilepsy.
https://doi.org/10.1002/14651858.CD008295.pub6
The Cochrane Database of Systematic Reviews; Shi LL, Bresnahan R et. al.

Aug 2nd, 2022 - This is an updated version of the Cochrane Review first published in 2011, and most recently updated in 2019. Epilepsy is a chronic and disabling neurological disorder, affecting approximately 1% of the population. Up to 30% of people with epileps...

Efficacy of Lenses in Abolishing Photoparoxysmal Responses
https://clinicaltrials.gov/ct2/show/NCT04076410

Jul 27th, 2022 - BACKGROUND Photosensitive epilepsy (PSE) is the most common of reflex epilepsies and represents approximately 10% of all new cases of epilepsy in the age range 7-19 years (Harding & Jeavons, 1994). Photosensitivity is the nuclear feature of PSE, i...

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT03083665

Jul 26th, 2022 - The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treat...

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Guidelines  6 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

European Stroke Organization guideline for the diagnosis and treatment of cerebral veno...
https://doi.org/10.1111/ene.13381
European Journal of Neurology; Ferro JM, Bousser MG et. al.

Aug 24th, 2017 - Current guidelines on cerebral venous thrombosis (CVT) diagnosis and management were issued by the European Federation of Neurological Societies in 2010. We aimed to update the previous European Federation of Neurological Societies guidelines usin...

Management issues for women with epilepsy--focus on pregnancy (an evidence-based review...
https://doi.org/10.1111/j.1528-1167.2009.02130.x
Epilepsia Harden CL, Pennell PB et. al.

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid and prenatal vitamin K use and the clinical implicatio...

Practice parameter update: management issues for women with epilepsy--focus on pregnanc...
https://doi.org/10.1212/WNL.0b013e3181a6b325
Neurology Harden CL, Pennell PB et. al.

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid use, prenatal vitamin K use, risk of hemorrhagic disease of the newborn, clinical implications o...

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Drugs  45 results see all →

Clinicaltrials.gov  233 results

Efficacy of Lenses in Abolishing Photoparoxysmal Responses
https://clinicaltrials.gov/ct2/show/NCT04076410

Jul 27th, 2022 - BACKGROUND Photosensitive epilepsy (PSE) is the most common of reflex epilepsies and represents approximately 10% of all new cases of epilepsy in the age range 7-19 years (Harding & Jeavons, 1994). Photosensitivity is the nuclear feature of PSE, i...

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT03083665

Jul 26th, 2022 - The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treat...

Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT05063877

Jul 25th, 2022 - EQU-201 is a Phase 2 randomized, double-blind, placebo-controlled study to evaluate dose-ranging safety, tolerability, and exploratory efficacy of adjunctive EQU-001 using the continuous reassessment method (CRM). 10 participants diagnosed with ep...

Brivaracetam Efficacy and Safety Study in Subjects With Partial Onset Seizures
https://clinicaltrials.gov/ct2/show/NCT01261325

Jul 22nd, 2022 - This study will evaluate the efficacy and safety of brivaracetam at doses of 100 and 200mg/day compared to placebo as adjunctive treatment in adult focal epilepsy subjects with partial onset seizures not fully controlled despite current treatment ...

Antiepileptic Drugs in Elderly Patients
https://clinicaltrials.gov/ct2/show/NCT05459597

Jul 15th, 2022 - The purpose is to study the population pharmacokinetics, effectiveness and safety of antiepileptic drug (phenytoin, carbamazepine, lamotrigine, levetiracetam, parempanel, etc) in elderly patients and recommend optimized dosage regimens.

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News  579 results

Antiseizure Medication Appears Safe in Pregnancy
https://www.medscape.com/viewarticle/971734

Apr 6th, 2022 - SEATTLE – Use of antiseizure medications while breastfeeding is not associated with differences in child cognitive outcomes at age 3, according to new results from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD...

Antiseizure medication appears safe in pregnancy
https://www.mdedge.com/neurology/article/253483/epilepsy-seizures/antiseizure-medication-appears-safe-pregnancy
Jim Kling

Apr 5th, 2022 - SEATTLE – Use of antiseizure medications while breastfeeding is not associated with differences in child cognitive outcomes at age 3, according to new results from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD.

Psychiatric and nonpsychiatric indications for mood stabilizers and select antiepileptics
https://www.mdedge.com/psychiatry/article/253224/bipolar-disorder/psychiatric-and-nonpsychiatric-indications-mood
Andrew Karas, PharmD, BCPP, Lauren Stummer, PharmD, BCPP et. al.

Apr 1st, 2022 - Mr. B, age 64, is being treated in the psychiatric clinic for generalized anxiety disorder.

FDA Okays New Med for Lennox-Gastaut Syndrome
https://www.medscape.com/viewarticle/971158

Mar 29th, 2022 - The US Food and Drug Administration (FDA) has approved fenfluramine (Fintepla) oral solution, a Schedule IV controlled substance, for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in children aged 2 years and older, the c...

Whole-plant Cannabis Linked to Large Reduction in Seizures
https://www.medscape.com/viewarticle/965756

Dec 29th, 2021 - Whole-plant cannabis is linked to a significant reduction in seizures in children with severe treatment-resistant epilepsy, early research suggests. In a small case series, children with severe treatment-resistant epilepsy treated with a range of ...

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Patient Education  1 results see all →