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About 10,468 results

ALLMedicine™ Antiepileptic Drugs Center

Research & Reviews  3,279 results

The microbiome-gut-brain axis in Epilepsy: Pharmacotherapeutic target from bench eviden...
https://doi.org/10.1111/ene.15767
European Journal of Neurology; Kundu S, Nayak S et. al.

Mar 8th, 2023 - Gut-brain axis confers to the bidirectional intimation between the gut and brain and modulates gut homeostasis and central nervous system through the hypothalamic-pituitary-adrenal axis, enteroendocrine system, neuroendocrine system, inflammatory ...

Antiepileptic drugs modulate Alzheimer-related tau aggregation in a neuronal activity-i...
https://doi.org/10.1159/000529915
Dementia and Geriatric Cognitive Disorders; Ito Y, Takeda S et. al.

Mar 7th, 2023 - A rapidly increasing number of patients with dementia present a serious social problem. Recently, the incidence of epilepsy in patients with Alzheimer's disease (AD) is increasing, drawing attention to the pathological relationship between the two...

Glioblastoma Medication
https://emedicine.medscape.com/article/283252-medication

Mar 7th, 2023 - Medication Summary The alkylating agent temozolomide is used for treatment of newly diagnosed glioblastoma, and the monoclonal antibody bevacizumab is used for treatment of recurrences. In addition, several medications are used for supportive care...

Cutaneous Adverse Drug Reactions: Regional Experience of a Global Challenge.
https://doi.org/10.2174/1574886318666230303085538
Current Drug Safety; Bushehri B, Mokhtarpoor A et. al.

Mar 6th, 2023 - Adverse drug reactions (ADR) are considered any harmful and unintended side effects associated with the use of a drug at the usual therapeutic dose, in which skin is involved in most cases. Therefore, the availability of epidemiological informatio...

Antiepileptic therapy in a patient with star fruit intoxication: A case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981371
Medicine Li A, Chen B et. al.

Mar 3rd, 2023 - It is rare for uremia patients to have epileptic seizures after eating star fruit, only a dozen cases are reported worldwide. Such patients usually have poor prognoses. Few patients had good prognoses, all of them were treated with expensive renal...

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Guidelines  6 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

European Stroke Organization guideline for the diagnosis and treatment of cerebral veno...
https://doi.org/10.1111/ene.13381
European Journal of Neurology; Ferro JM, Bousser MG et. al.

Aug 24th, 2017 - Current guidelines on cerebral venous thrombosis (CVT) diagnosis and management were issued by the European Federation of Neurological Societies in 2010. We aimed to update the previous European Federation of Neurological Societies guidelines usin...

Management issues for women with epilepsy--focus on pregnancy (an evidence-based review...
https://doi.org/10.1111/j.1528-1167.2009.02130.x
Epilepsia Harden CL, Pennell PB et. al.

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid and prenatal vitamin K use and the clinical implicatio...

Practice parameter update: management issues for women with epilepsy--focus on pregnanc...
https://doi.org/10.1212/WNL.0b013e3181a6b325
Neurology Harden CL, Pennell PB et. al.

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid use, prenatal vitamin K use, risk of hemorrhagic disease of the newborn, clinical implications o...

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Drugs  63 results see all →

Clinicaltrials.gov  236 results

Nabilone for Agitation in Frontotemporal Dementia
https://clinicaltrials.gov/ct2/show/NCT05742698

Feb 24th, 2023 - While the search for disease modifying treatment of frontotemporal dementia (FTD) remains elusive, on a day-to-day basis, clinicians struggle to help manage the severe neuropsychiatric symptoms of FTD. Agitation, irritability and aggression are co...

Biomarkers for Tuberous Sclerosis Complex (BioTuScCom)
https://clinicaltrials.gov/ct2/show/NCT02654340

Feb 10th, 2023 - Tuberous Sclerosis Complex (TSC) is an autosomal dominant genetic disorder characterized by the growth of numerous tumors in different body parts related to dysregulation of the mechanistic target of rapamycin (mTOR) pathway. The overall incidence...

Metformin Efficacy and Safety in Epileptic Patients
https://clinicaltrials.gov/ct2/show/NCT05722951

Feb 10th, 2023 - The goal of this clinical trial is to Evaluating Metformin Efficacy and Safety when Co-administered with Antiepileptic Drugs in Patients with Seizures. The main question it aims to answer is: Does metformin have beneficial effect on epileptic pati...

Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT05063877

Jan 31st, 2023 - EQU-201 is a Phase 2 randomized, double-blind, placebo-controlled study to evaluate dose-ranging safety, tolerability, and exploratory efficacy of adjunctive EQU-001 using the continuous reassessment method (CRM). 10 participants diagnosed with ep...

Minimally Invasive Surgical Epilepsy Trial for Temporal Lobe Epilepsy
https://clinicaltrials.gov/ct2/show/NCT05019404

Dec 30th, 2022 - Temporal lobe epilepsy (TLE) is a chronically neurological disease characterized by progressive seizures, followed by a latency period of several years after various injuries including febrile seizures, infection, trauma, tumors, and vascular malf...

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News  602 results

Epilepsy Drugs May Up Risk of Parkinson's
https://www.medpagetoday.com/neurology/seizures/102398

Dec 27th, 2022 - Taking antiepileptic drugs (AEDs) was associated with a subsequent diagnosis of Parkinson's disease (PD), a U.K.-based case control study suggested. There was a significant association between AED prescriptions and incident Parkinson's disease (OR...

Risk for inpatient constipation similar with erenumab and other anti-CGRP mAb in migraine
https://www.mdedge.com/migraine-icymi/article/258817/headache-migraine/risk-inpatient-constipation-similar-erenumab-and

Oct 24th, 2022 - Key clinical point: The risk for inpatient constipation within 90 days of treatment initiation was similar in patients with migraine initiating erenumab vs other anti-calcitonin gene-related peptide (CGRP) receptor monoclonal antibodies (mAb), but.

Atezolizumab Plus Vemurafenib/Cobimetinib Produces Intracranial Activity in BRAF V600–Mutant Melanoma With CNS Metastases
https://www.onclive.com/view/atezolizumab-plus-vemurafenib-cobimetinib-produces-intracranial-activity-in-braf-v600-mutant-melanoma-with-cns-metastases

Sep 27th, 2022 - The addition of atezolizumab (Tecentriq) to vemurafenib (Zelboraf) and cobimetinib (Cotellic) produced promising intracranial activity in patients with BRAF V600–mutated advanced melanoma and central nervous system (CNS) metastases, according to d...

Recent Neurology Data Highlight Treatments to Avoid
https://www.medscape.com/viewarticle/978463

Aug 25th, 2022 - This transcript has been edited for clarity. Dear colleagues, I am Christoph Diener from the University of Duisburg-Essen in Germany. Today I would like to share with you results from six interesting studies published in July 2022. Risk for Neurod...

Use of These Epilepsy Meds During Pregnancy Linked to Child's Autism
https://www.medpagetoday.com/neurology/seizures/99001

Jun 1st, 2022 - Children exposed prenatally to antiseizure medications were at greater risk of autism spectrum disorders (ASD) and intellectual disability (ID), according to a population-based cohort study. By approximately age 8 years, children were two to four ...

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Patient Education  1 results see all →