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About 10,310 results

ALLMedicine™ Antiepileptic Drugs Center

Research & Reviews  3,233 results

The Significance of Statin Associated Muscle Symptoms and Its Impact on Patients Adhere...
https://doi.org/10.1097/FJC.0000000000001386
Journal of Cardiovascular Pharmacology; Al-Makhamreh HK, Toubasi AA et. al.

Dec 3rd, 2022 - Statin Associated Muscle Symptoms (SAMS) are one of the most common side effects of statins. This study aimed to explore the significance of SAMS among statin users by comparing statin users with a control group. To achieve our aims, a propensity ...

Chemical Kindling as an Experimental Model to Assess the Conventional Drugs in the Trea...
https://doi.org/10.2174/1871527322666221128155813
CNS & Neurological Disorders Drug Targets; Aghdash SN, Foroughi G

Nov 30th, 2022 - Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality today, which will surpass many infectious diseases in the coming years/ decades. Post-traumatic epilepsy (PTE) is one of the most common debilitating consequences...

Interactions between the gut microbiome and ketogenic diet in refractory epilepsy.
https://doi.org/10.1016/bs.irn.2022.06.002
International Review of Neurobiology; Özcan E, Lum GR et. al.

Nov 26th, 2022 - Epilepsy is one of the most common neurological diseases globally, afflicting approximately 50 million people worldwide. While many antiepileptic drugs exist, an estimated one-third of individuals do not respond to available medications. The high ...

Caffeine impairs anticonvulsant effects of levetiracetam in the maximal electroshock se...
https://doi.org/10.1515/jbcpp-2022-0224
Journal of Basic and Clinical Physiology and Pharmacology; Chwedorowicz R, Łukawski K et. al.

Nov 25th, 2022 - Caffeine is the most widely used psychoactive substance in the world. Animal studies indicate that acute caffeine exposure at high doses may induce seizures and diminish the anticonvulsant activity of antiepileptic drugs (AEDs) at much lower doses...

Lamotrigine induced priapism in children: case analysis and literature review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703579
The Journal of International Medical Research; Ge J, Cao SS et. al.

Nov 25th, 2022 - Lamotrigine is an antiepileptic drug that can be used to control many types of seizures as a single-agent or an add-on therapy in patients over 2 years of age. In addition to common adverse reactions, this current case report describes a paediatri...

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Guidelines  6 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

European Stroke Organization guideline for the diagnosis and treatment of cerebral veno...
https://doi.org/10.1111/ene.13381
European Journal of Neurology; Ferro JM, Bousser MG et. al.

Aug 24th, 2017 - Current guidelines on cerebral venous thrombosis (CVT) diagnosis and management were issued by the European Federation of Neurological Societies in 2010. We aimed to update the previous European Federation of Neurological Societies guidelines usin...

Management issues for women with epilepsy--focus on pregnancy (an evidence-based review...
https://doi.org/10.1111/j.1528-1167.2009.02130.x
Epilepsia Harden CL, Pennell PB et. al.

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid and prenatal vitamin K use and the clinical implicatio...

Practice parameter update: management issues for women with epilepsy--focus on pregnanc...
https://doi.org/10.1212/WNL.0b013e3181a6b325
Neurology Harden CL, Pennell PB et. al.

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid use, prenatal vitamin K use, risk of hemorrhagic disease of the newborn, clinical implications o...

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Drugs  56 results see all →

Clinicaltrials.gov  235 results

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT03083665

Oct 10th, 2022 - The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treat...

A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI
https://clinicaltrials.gov/ct2/show/NCT05567042

Oct 5th, 2022 - This study included diagnostic trials and case-control studies, which were observational studies with no intervention. First, the demographic and clinical information of epilepsy patients in the Neurology Department of Xijing Hospital were collect...

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)
https://clinicaltrials.gov/ct2/show/NCT02091206

Sep 28th, 2022 - This multi-center study consisted of 2 parts: Part A and Part B. Only Part A is described in this record. Part A was a randomized, double-blind 21-day treatment study period. Participants were randomized to one of 3 doses of active drug or placebo...

Behavioral Economics and Adherence in Teens (BEAT!)
https://clinicaltrials.gov/ct2/show/NCT03958331

Sep 23rd, 2022 - Non-adherence to antiepileptic drugs (AEDs) is a common problem (i.e., 58% of patients have some level of non-adherence) for youth with epilepsy, with potentially devastating consequences. Adolescents with epilepsy represent a particularly vulnera...

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex
https://clinicaltrials.gov/ct2/show/NCT05534672

Sep 9th, 2022 - This is a two-arm, randomized, double-blind, placebo controlled study to evaluate the efficacy, tolerability, and safety of rapamycin versus placebo in a drug resistant epilepsy associated with TSC. The study consists of 3 phases for each patient:...

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News  593 results

Atezolizumab Plus Vemurafenib/Cobimetinib Produces Intracranial Activity in BRAF V600–Mutant Melanoma With CNS Metastases
https://www.onclive.com/view/atezolizumab-plus-vemurafenib-cobimetinib-produces-intracranial-activity-in-braf-v600-mutant-melanoma-with-cns-metastases

Sep 27th, 2022 - The addition of atezolizumab (Tecentriq) to vemurafenib (Zelboraf) and cobimetinib (Cotellic) produced promising intracranial activity in patients with BRAF V600–mutated advanced melanoma and central nervous system (CNS) metastases, according to d...

Recent Neurology Data Highlight Treatments to Avoid
https://www.medscape.com/viewarticle/978463

Aug 25th, 2022 - This transcript has been edited for clarity. Dear colleagues, I am Christoph Diener from the University of Duisburg-Essen in Germany. Today I would like to share with you results from six interesting studies published in July 2022. Risk for Neurod...

Use of These Epilepsy Meds During Pregnancy Linked to Child's Autism
https://www.medpagetoday.com/neurology/seizures/99001

Jun 1st, 2022 - Children exposed prenatally to antiseizure medications were at greater risk of autism spectrum disorders (ASD) and intellectual disability (ID), according to a population-based cohort study. By approximately age 8 years, children were two to four ...

Antiseizure Medication Appears Safe in Pregnancy
https://www.medscape.com/viewarticle/971734

Apr 6th, 2022 - SEATTLE – Use of antiseizure medications while breastfeeding is not associated with differences in child cognitive outcomes at age 3, according to new results from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD...

Antiseizure medication appears safe in pregnancy
https://www.mdedge.com/neurology/article/253483/epilepsy-seizures/antiseizure-medication-appears-safe-pregnancy
Jim Kling

Apr 5th, 2022 - SEATTLE – Use of antiseizure medications while breastfeeding is not associated with differences in child cognitive outcomes at age 3, according to new results from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD.

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Patient Education  1 results see all →