About 833 results

ALLMedicine™ First Seizure Center

Research & Reviews  287 results

Risk of seizure recurrence in people with single seizures and early epilepsy - Model de...
Seizure Bonnett LJ, Kim L et. al.

Dec 3rd, 2021 - Following a single seizure, or recent epilepsy diagnosis, it is difficult to balance risk of medication side effects with the potential to prevent seizure recurrence. A prediction model was developed and validated enabling risk stratification whic...

PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of ...
Journal of Neurophysiology; Mackenzie-Gray Scott CA, Parrish RR et. al.

Nov 18th, 2021 - The transcriptional coactivator, PGC-1α (peroxisome proliferator activated receptor gamma coactivator 1α), plays a key role coordinating energy requirement within cells. Its importance is reflected in the growing number of psychiatric and neurolog...

Paroxysmal slow wave events predict epilepsy following a first seizure.
Epilepsia Zelig D, Goldberg I et. al.

Nov 10th, 2021 - Management of a patient presenting with a first seizure depends on the risk of additional seizures. In clinical practice, the recurrence risk is estimated by the treating physician using the neurological examination, brain imaging, a thorough hist...

Arteriovenous Malformations

Nov 2nd, 2021 - Practice Essentials Arteriovenous malformations (AVMs) are congenital lesions composed of a complex tangle of arteries and veins connected by one or more fistulae (see the image below). They most commonly occur in young adults, with morbidity and ...

Arteriovenous Malformations Clinical Presentation

Nov 2nd, 2021 - History Arteriovenous malformations (AVMs) tend to be clinically silent until the presenting event occurs. Therefore, the diagnosis usually is made at the time of the first seizure or hemorrhage. A history of minor learning disability is present i...

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Drugs  4 results see all →

Clinicaltrials.gov  4 results

Is Protein S100B a Predictor of First-to-chronic Seizure Conversion in Adults?

Dec 19th, 2020 - The secondary objectives of this study are to investigate the: A) Prognostic capacity of serum S100B levels to predict seizure recurrence. B) Association between the variation (%) of serum S100B levels between first seizure episode and scheduled f...

A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With Epilepsy

Jun 8th, 2011 - Topiramate is a drug that is currently widely used for the treatment of seizures in adults and pediatric patients (2 to 16 years of age). This is a randomized, double-blind, parallel-group study to evaluate the effectiveness and safety of two dosa...

Utility of Laboratory Testing for Children With Seizure in Emergency Department

May 14th, 2010 - Objective: To evaluate the predisposing factors associated with abnormal laboratory findings in patients who came to the emergency room due to a first seizure. Methods: Patients were divided into separate groups based on normal and abnormal labora...

Characteristics of Blood- Brain Barrier Permeability in Neurological Patients

Jan 9th, 2007 - Traumatic brain injury (TBI) is one of the most common traumatic events, occurring in approximately 200 per 100,000, and is a known risk factor for later development of epileptic seizures. This occurs in up to 17% of TBI patients, and accounts for...

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News  38 results

Preventive Treatment Delays First Seizure Onset in Tuberous Sclerosis Complex

Oct 22nd, 2020 - In patients with tuberous sclerosis complex (TSC), preventive treatment with vigabatrin is safe and changes the natural history of seizures, according to research presented at the 2020 CNS-ICNA Conjoint Meeting, held virtually this year. This trea...

Off to College: Safe to Stop His Antiepileptic Drug?

Mar 23rd, 2020 - In this edition of Cases in Deprescribing, I present another clinical scenario drawn from my own practice. I'll tell you what I plan to do, but I'm most interested in crowdsourcing a response from all of you to collectively determine best practice...

ECG Challenge: Teen With His First Seizure

Nov 6th, 2019 - The correct diagnosis is long QT, torsade de pointes (Figure 2). Figure 2. Courtesy of Dr Podrid. Discussion The first QRS complex is narrow and supraventricular (*). It is followed by a rapid and irregular rhythm with a rate of up to 300 beats/mi...

ECG Challenge: Teen With His First Seizure

Nov 6th, 2019 - A 17-year-old boy is admitted to the hospital after suffering a seizure at home. He has never had a seizure before but has had episodes of lightheadedness and presyncope. While being monitored on telemetry, he complains of lightheadedness, and the...

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