About 69,990 results

ALLMedicine™ Seizures Center

Research & Reviews  21,574 results

Forecasting Seizure Clusters from Chronic Ambulatory Electrocorticography.
Epilepsia Ilyas A, Hoffman C et. al.

Jun 26th, 2022 - Seizure clusters are seizures that occur in rapid succession during periods of heightened seizure risk and are associated with substantial morbidity and sudden unexpected death in epilepsy. The objective of this feasibility study is to evaluate th...

The role of Na+ -K+ -ATPase in the epileptic brain.
CNS Neuroscience & Therapeutics; Sun J, Zheng Y et. al.

Jun 26th, 2022 - Na+-K+-ATPase, a P-type ATP-powered ion transporter on cell membrane, plays a vital role in cellular excitability. Cellular hyperexcitability, accompanied by hypersynchronous firing, is an important basis for seizures/epilepsy. An increasing numbe...

Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerat...
https://doi.org/10.1007/s12017-022-08713-2 10.1016/j.tibs.2015.12.006 10.1016/j.neuron.2012.03.023 10.1016/S0896-6273(00)80230-5 10.1016/j.cmet.2018.01.016 10.1523/JNEUROSCI.1446-19.2019 10.1038/ncomms2238 10.1016/j.cmet.2015.10.013 10.1038/s41573-020-0072-x 10.1161/CIRCRESAHA.119.315767 10.1002/art.39618 10.1016/j.nbd.2017.06.009 10.1371/journal.pone.0196223 10.1073/pnas.91.8.3270 10.1038/s41380-019-0483-4 10.1016/j.molcel.2011.07.019 10.1111/jnc.13230 10.1073/pnas.1111308108 10.1016/bs.irn.2020.03.015 10.1016/j.neurobiolaging.2012.11.023 10.1523/ENEURO.0418-20.2020 10.1046/j.1471-4159.1997.69010273.x 10.1042/BJ20100791 10.1016/j.tins.2017.01.002 10.1016/0006-8993(90)91355-K 10.1016/0197-4580(94)00150-2 10.1523/JNEUROSCI.15-09-06239.1995 10.1046/j.1471-4159.1997.68010255.x 10.1523/JNEUROSCI.17-03-01046.1997 10.1016/bs.irn.2020.01.006 10.1016/0896-6273(93)90315-I 10.3233/JAD-150544 10.1038/nn.2583 10.1016/j.tins.2021.01.001 10.1093/hmg/ddx100 10.1016/j.neuron.2014.10.024 10.1016/j.bbadis.2020.165849 10.1002/ana.24794 10.1016/S1474-4422(17)30044-3 10.1111/jgs.17101 10.1016/j.celrep.2020.108169 10.1016/j.neurobiolaging.2014.06.009
Neuromolecular Medicine; Perone I, Ghena N et. al.

Jun 25th, 2022 - Aging is the major risk factor for Alzheimer's disease (AD). Mitochondrial dysfunction and neuronal network hyperexcitability are two age-related alterations implicated in AD pathogenesis. We found that levels of the mitochondrial protein deacetyl...

Persistent knowledge gaps between 2005 and 2020 in women with epilepsy: Comparison of m...
Seizure Mann C, Zinger E et. al.

Jun 25th, 2022 - Epilepsy is a chronic condition that can affect patients of all ages. Women with epilepsy (WWE) require access to specific counseling and information regarding issues related to contraception, pregnancy, and hormonal effects on seizure control and...

The effectiveness and tolerability of clobazam in the pediatric population: Adjunctive ...
Epilepsy Research; Kamaşak T, Serdaroğlu E et. al.

Jun 25th, 2022 - To evaluate the effectiveness and tolerability of clobazam therapy in the pediatric population in terms of seizure semiology, epileptic syndromes, and etiological subgroups. A retrospective cohort study was conducted consisting of 1710 epileptic c...

see more →

Guidelines  21 results

Minimum standards for inpatient long-term video-electroencephalographic monitoring: A c...
Epilepsia Tatum WO, Mani J et. al.

Dec 14th, 2021 - The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League Agains...

ACR Appropriateness Criteria® Seizures-Child.
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 7th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

ACR Appropriateness Criteria® Seizures and Epilepsy.
Journal of the American College of Radiology : JACR; , Lee RK et. al.

May 7th, 2020 - Seizures and epilepsy are a set of conditions that can be challenging to diagnose, treat, and manage. This document summarizes recommendations for imaging in different clinical scenarios for a patient presenting with seizures and epilepsy. MRI of ...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

see more →

Drugs  2,191 results see all →

Clinicaltrials.gov  1,471 results

Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

Jun 24th, 2022 - Niemann-Pick type C disease (NPC) is an autosomal recessive, lysosomal storage disorder characterized by accumulation of cholesterol and gangliosides. NPC is a rare (estimated prevalence of 1:120,000-150,000) neurodegenerative disorder with a wide...

Tumor Related Epilepsy

Jun 24th, 2022 - Objective This protocol is being performed to 1) study the natural history and disease pathogenesis in patients with tumor related epilepsy, 2) collect prospective data on seizure outcomes following standard surgical treatment of brain tumors with...

Mothers' Thoughts About Kids and Eating

Jun 24th, 2022 - Purpose This study will investigate the impact of health information on choices that parents make about food for their children. Participants will use a virtual reality model of a buffet to make food choices. Mothers and fathers with a biological ...

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Jun 24th, 2022 - Propionic acidemia (PA) is one of the most common inborn errors of organic acid metabolism. Although this disorder is now routinely detected in the immediate neonatal period on the US newborn screen, clinical outcomes are poor despite timely and a...

Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures

Jun 24th, 2022 - Objectives: The study investigates the neurobiological correlates of conversion disorder (CD). The primary objectives are to investigate in CD patients: The role of emotional valence in an implicit emotional processing task (COMPLETE) The frequenc...

see more →

News  2,593 results

Severe ipsilateral headache

Jun 14th, 2022 - On the basis of the patient's presentation, family history, and personal history of headache, she seems to be presenting with hemiplegic migraine, an uncommon migraine subtype characterized by recurrent headaches associated with temporary unilater.

Frustrated With Delays, Doctors Take Aim at Prior Authorization

May 26th, 2022 - Last December, a young patient was admitted to Nationwide Children's Hospital in Columbus, Ohio, after several medications had failed to quell the child's relentless seizures. A hospital pediatrician, Vignesh Doraiswamy, consulted with neurologist...

Downtime? Enjoy it
Allan M. Block, MD

May 23rd, 2022 - Everything in medicine, and pretty much the universe, is based on averages. Average reduction of seizures, average blood levels, average response to treatment, average insurance reimbursement, average time spent with a new consult.

Phase 3 Data on Fenfluramine for Lennox-Gastaut Published

May 5th, 2022 - A daily dose of fenfluramine (Fintepla, UCB), when added to an existing anti-epileptic treatment regimen, significantly reduced the frequency of drop seizures associated with Lennox-Gastaut syndrome (LGS) in the phase 3 study that led to US approv...

Air Pollution a Seizure Trigger for Patients With Epilepsy

May 2nd, 2022 - Elevated concentrations of carbon monoxide (CO) due to air pollution increases the risk of epileptic seizures, a unique new study suggests. The link between daily outdoor CO exposure and seizure risk was particularly evident for subclinical seizur...

see more →

Patient Education  146 results see all →