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Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and...
PLoS Medicine; Shanthanna H, Gilron I et. al.

Aug 15th, 2017 - Chronic Low Back Pain (CLBP) is very common, with a lifetime prevalence between 51% and 80%. In majority, it is nonspecific in nature and multifactorial in etiology. Pregabalin (PG) and Gabapentin (GB) are gabapentinoids that have demonstrated benefit in neuropathic pain conditions. Despite no clear rationale, they are increasingly used for nonspecific CLBP. They necessitate prolonged use and a...

2019 Supportive Care: Anxiety, Depression, and Low Social Support Are Significant Factors in Cancer Pain Intensity

Oct 21st, 2019 - Pain is one of the most common symptoms associated with cancer and its treatment, and feelings of anxiety and depression can intensify the level of pain patients experience, according to the results from a study by Galloway et al that will be presented at the 2019 Supportive Care in Oncology Symposium (Abstract 76). However, authors also reported that having greater social support can help miti...

Cochrane for Clinicians: Vaccines for Preventing Influenza in Healthy Children, Healthy Adults, and Older Adults
American Family Physician;

Jul 31st, 2019 - Clinical Question Do influenza vaccines reduce the risk of influenza in healthy children, healthy adults, and older adults? Evidence-Based Answer Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absentee...

FDA approves first generics of Lyrica

Jul 21st, 2019 - On July 19, the U.S. Food and Drug Administration approved multiple applications for first generics of Lyrica (pregabalin) for the management of neuropathic pain associated with diabetic peripheral neuropathy, for the management of postherpetic neuralgia, as an adjunctive therapy for the treatment of partial onset seizures in patients 17 years of age and older, for the management of fibromyalgi...

Randomized Controlled Phase 2a Study of RPh201 in Previous Nonarteritic Anterior Ischemic Optic Neuropathy
Rath, E. et. al.

Jul 21st, 2019 - Background: No proven treatment exists for nonarteritic anterior ischemic optic neuropathy (NAION), either in the acute or late phase. Objective: To assess safety and changes in visual function and structure after RPh201/placebo treatment in participants with previous NAION. Design and Setting: Phase 2a, single-site, prospective, randomized, placebo-controlled, double-masked trial (regist...

Acupuncture for Pain
American Family Physician; Kelly, R. et. al.

Jul 14th, 2019 - Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry needling, often result in reported pain improvement. Multiple factors may contribute to variability in acupuncture's therapeutic effects, including n...

61st Annual Scientific Meeting of the American Headache Society Poster Presentations

Jul 11th, 2019 - 61st Annual Scientific Meeting of the American Headache Society POSTER PRESENTATIONS Friday, July 12 and Saturday, July 13, 2019

61st Annual Scientific Meeting | American Headache Society

Jul 10th, 2019 - The Annual Scientific Meeting is designed for physicians, psychologists, scientists, researchers, physician assistants, nurse practitioners, and other health professionals involved in the care of patients with head, neck, and orofacial pain.

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache

Jun 25th, 2019 - This clinical policy from the American College of Emergency Physicians addressed key issues in the evaluation and management of adult patients presenting to the emergency department with acute headache. A writing subcommittee conducted a systematic review of the literature to derive evidence-based recommendations to answer the following clinical questions: (1) In the adult emergency departm...

Statement on the FDA’s benefit-risk framework for evaluating opioid analgesics

Jun 19th, 2019 - Addressing the crisis of opioid addiction is an issue of great concern for our nation and remains a top public health priority for the FDA. The agency continues to take new steps to confront this crisis, while also paying careful attention to the needs of patients in accessing appropriate pain management. Opioids present unique challenges: they have benefits when used as prescribed yet have ver...

Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States
Jiang, C. et. al.

Jun 19th, 2019 - The population of cancer survivors in the United States is growing rapidly.1 In 2016, the number of survivors was 15.5 million; with the aging of the population and advances in early detection and treatment methods, this number is expected to reach 26.1 million by 2040.1 Chronic pain is one of the most common long-term effects of cancer treatment and has been linked with an impaired quality of ...

Health Insurance Design and Conservative Therapy for Low Back Pain
The American Journal of Managed Care;

Jun 6th, 2019 - Objectives: To determine the association of health insurance benefit design features with choice of early conservative therapy for patients with new-onset low back pain (LBP). Study Design: Observational study of 117,448 commercially insured adults 18 years or older presenting with an outpatient diagnosis of new-onset LBP between 2008 and 2013 as recorded in the OptumLabs Data Warehouse. ...

FDA approves first treatment for episodic cluster headache that reduces the frequency of attacks

Jun 3rd, 2019 - The U.S. Food and Drug Administration today approved Emgality (galcanezumab-gnlm) solution for injection for the treatment of episodic cluster headache in adults. “Emgality provides patients with the first FDA-approved drug that reduces the frequency of attacks of episodic cluster headache, an extremely painful and often debilitating condition,” said Eric Bastings, M.D., deputy director of ...

Pain Management Best Practices Interagency Task Force Report

May 7th, 2019 - Patients with acute and chronic pain in the United States face a crisis because of significant challenges in obtaining adequate care, resulting in profound physical, emotional, and societal costs. According to the Centers for Disease Control and Prevention, 50 million adults in the United States have chronic daily pain, with 19.6 million adults experiencing highimpact chronic pain that interf...

Diagnostic Tests for Low Back Disorders

Mar 31st, 2019 - This article summarizes ACOEM's evidence-based diagnostic guidelines for low back disorders. Recommendations are given for these diagnostic tests: functional capacity evaluations, roentgenograms (x-rays), magnetic resonance imaging (MRI), computerized tomography, myelography, bone scans, single proton emission computed tomography, electromyography, surface electromyography, ultrasound, thermogr.

NCCN 2019 Annual Conference Includes Focus on Patient Experience with Innovative Therapies, Plus Updates on Biomarkers, Biosimilars, and the Latest Research on Cancer Care

Mar 3rd, 2019 - More than 1,500 cancer care professionals are meeting in Orlando, Florida, March 21-23, for the NCCN 2019 Annual Conference, presented by the National Comprehensive Cancer Network® (NCCN®)—an alliance of 28 leading cancer centers. The conference offers more than 25 sessions presenting the latest treatment recommendations for lung, breast, prostate, colon, and other cancers, including new and em...

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline
Vandvik, P.,et al

Feb 5th, 2019 - Clinical question: Do adults with atraumatic shoulder pain for more than 3 months diagnosed as subacromial pain syndrome (SAPS), also labelled as rotator cuff disease, benefit from subacromial decompression surgery? This guideline builds on to two recent high quality trials of shoulder surgery. Current practice: SAPS is the common diagnosis for shoulder pain with several first line treatment op.

Challenges with Implementing the Centers for Disease Control and Prevention Opioid Guideline: A Consensus Panel Report
Kroenke, K. et. al.

Jan 24th, 2019 - A national crisis of opioid-related morbidity, mortality, and misuse has led to initiatives to address the appropriate role of opioids to treat pain. Deployment of a guideline from the Centers for Disease Control and Prevention to reduce the risks of opioid therapy has raised substantial clinical and public policy challenges. The agency anticipated implementation challenges and committed to ree...

The American Headache Society Position Statement On Integrating New Migraine Treatments Into Clinical Practice

Dec 9th, 2018 - Objective To provide healthcare professionals with updated guidance in the use of novel preventive and acute treatments for migraine in adults. Background The principles of preventive and acute pharmacotherapy for patients with migraine have been outlined previously, but the emergence of new technologies and treatments, as well as new formulations of previously established treatments, has ...

Opioids in Nursing Homes

Dec 3rd, 2018 - AMDA – The Society for Post-Acute and Long-Term Care Medicine has two primary policies related to opioids in nursing homes: 1. Provide access to opioids when indicated to relieve suffering and to improve or maintain function, and 2. Promote opioid tapering, discontinuation and avoidance of opioids when the above goals are not achievable, to prevent adverse events, dependence and diversion.