About 533 results

ALLMedicine™ Neurosarcoidosis Center

Research & Reviews  199 results

A prospective, one-year follow-up study of patients newly diagnosed with neurosarcoidosis.
Journal of Neuroimmunology; Byg KE, Illes Z et. al.

Jun 20th, 2022 - Twenty patients with newly diagnosed neurosarcoidosis were examined for multiple outcomes in an observational cohort study with 12-month follow-up. The patients' contrast-enhancing lesions on MRI scans reduced during treatment (p < 0.0001). The me...

Distinguishing CNS neurosarcoidosis from multiple sclerosis and an approach to "overlap...
Journal of Neuroimmunology; Chan F, Riminton DS et. al.

Jun 12th, 2022 - Neurosarcoidosis is an important diagnosis to exclude in the work-up for suspected multiple sclerosis (MS). The distinction between the two conditions is usually possible due to characteristic clinical manifestations, magnetic resonance imaging (M...

Clinical features and diagnosis of neurosarcoidosis - review article.
Journal of Neuroimmunology; Barreras P, Stern BJ

May 7th, 2022 - Neurosarcoidosis affects 5-26% of patients with systemic sarcoidosis and can be the first or only manifestation of the disease. Neurosarcoidosis can affect any part of the nervous system with heterogeneous clinical manifestations and imaging appea...

The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but no...
Journal of Neuroimmunology; Paley MA, Baker BJ et. al.

Apr 12th, 2022 - The tissue-specific drivers of neurosarcoidosis remain poorly defined. To identify cerebrospinal fluid (CSF) specific, antigen-driven T and B cell responses, we performed single-cell RNA sequencing of CSF and blood cells from neurosarcoid particip...

Teaching Video NeuroImage: Parinaud Syndrome Due to Ventriculoperitoneal Shunt Malfunct...
Neurology Frank A, Weber C et. al.

Apr 6th, 2022 - Teaching Video NeuroImage: Parinaud Syndrome Due to Ventriculoperitoneal Shunt Malfunction in a Patient With Neurosarcoidosis.|2022|Frank A,Weber C,Bendig J,Schaefer J,|complications,diagnostic imaging,diagnostic imaging,surgery,adverse effects,

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Clinicaltrials.gov  3 results

Combined Analysis of Inflammatory Biomarkers for CNS Autoimmune Diseases Diagnostic

Sep 30th, 2021 - Project rationale: Since 2017, multiple sclerosis diagnosis should match the new McDonald criteria in which a "no better explanation than MS" should be fulfilled. However, many patients present with red flags that lead to a complex diagnostic work...

Neurosarcoidosis : Initial Presentation and Disease Course

Jun 3rd, 2021 - Sarcoidosis is a systemic inflammatory disease which a 10-20/100.000/year incidence rate. The nervous system is found to be affected in 5-10% in clinical series, rising to 14-27% in post-mortem studies. Mortality is as high as 5% mainly due to car...

Analysis of the Distribution of Regulatory B Cells in Blood of Multiple Sclerosis Patients

Sep 11th, 2020 - Multiple sclerosis (MS) is a progressive immuno-inflammatory and degenerative disease of the central nervous system (CNS) and represents the second most common cause of disability in young people. The pathophysiologic mechanisms involved are compl...

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News  11 results

Intestinal IgA-Producing B Cells Help Curb CNS Inflammation in MS

Dec 7th, 2020 - NEW YORK (Reuters Health) - During a multiple sclerosis (MS) exacerbation, specific IgA-producing B cells in the intestines travel to inflamed sites in the central nervous system (CNS), exerting an anti-inflammatory effect, researchers say. Princi...

Brain Activity in 'Unresponsive' Patients May Predict Recovery

Jun 27th, 2019 - About one in six clinically unresponsive ICU patients showed electroencephalography (EEG) patterns of brain activity when spoken to soon after acute brain injury, a single-center study showed. In 16 of 104 (15%) unresponsive patients, a machine-le...

No Consensus Treatment for Neurosarcoidosis

Feb 28th, 2018 - NAPLES, FL—Although patients with symptomatic neurosarcoidosis account for approximately 5% to 15% of people with systemic sarcoidosis, making it a rare manifestation of an uncommon disorder, neurosarcoidosis is associated with substantial morbidi.

Autoimmune Neurology: A New, Rapidly Evolving Subspecialty

Dec 18th, 2017 - An emerging new subspecialty is gaining ground as more fellowships and a growing body of research spur interest in the field of autoimmune neurology. Unlike neuroimmunology, autoimmune neurology's focus is much broader than multiple sclerosis (MS)...

Consider Optic Nerve Head Edema in Some ED Patients

Jun 2nd, 2017 - NEW YORK (Reuters Health) - Emergency department physicians should check certain patients for optic nerve head edema (ONHE) by fundus photography, researchers say. "The FOTO-ED study showed that non-mydriatic retinal photography in the emergency d...

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