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About 14,114 results

ALLMedicine™ Spasticity Center

Research & Reviews  6,315 results

Interventional Approaches to Pain and Spasticity Related to Cerebral Palsy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901135
Psychopharmacology Bulletin; Peck J, Urits I et. al.

Feb 26th, 2021 - This review will cover seminal and emerging evidence on interventional therapy chronic pain in cerebral palsy (CP). It will cover the background and burden of disease, present the current options, and then weigh the evidence that is available to s...

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic l...
https://doi.org/10.1080/15548627.2021.1891848
Autophagy Khundadze M, Ribaudo F et. al.

Feb 23rd, 2021 - Hereditary spastic paraplegia (HSP) denotes genetically heterogeneous disorders (SPGs) characterized by leg spasticity due to degeneration of corticospinal axons. SPG11 and SPG15 have a similar clinical course and together are the most prevalent a...

Early brain imaging predictors of post-stroke spasticity.
https://doi.org/10.2340/16501977-2803
Journal of Rehabilitation Medicine; Ri S, Glaess-Leistner S et. al.

Feb 22nd, 2021 - Post-stroke spasticity is a major factor disturbing rehabilitation and functional recovery in stroke survivors. Clinical predictors of post-stroke spasticity have often been discussed, but brain image predictors for spasticity have been insufficie...

Longitudinal goal attainment with integrated upper limb spasticity management including...
https://doi.org/10.2340/16501977-2801
Journal of Rehabilitation Medicine; Turner-Stokes L, Jacinto J et. al.

Feb 22nd, 2021 - To assess the longitudinal effects of integrated spasticity management incorporating repeated cycles of botulinum toxin A type A (BoNT-A) over 2 years. The Upper Limb International Spasticity study was a prospective, observational, cohort study fo...

Potential contributing factors to upper limb associated reactions in people with acquir...
https://doi.org/10.1080/09638288.2021.1887945
Disability and Rehabilitation; Kahn MB, Clark RA et. al.

Feb 22nd, 2021 - To determine which potential contributing factors are associated with upper limb associated reaction (AR) expression in individuals with acquired brain injury (ABI). Forty-two participants underwent three-dimensional motion analysis at self-select...

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Guidelines  15 results

FDA Approves Botox® (Onabotulinumtoxina) For Pediatric Patients With Lower Limb Spasticity, Excluding Spasticity Caused By Cerebral Palsy
https://www.allergan.com/News/Details/2019/10/FDA%20Approves%20BOTOX%20onabotulinumtoxinA%20for%20Pediatric%20Patients%20with%20Lower%20Limb%20Spasticity%20Excluding%20Sp

Oct 23rd, 2019 - Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) approved the company's supplemental Biologics License Application (sBLA) for BOTOX® for the treatment of pediatric patients (2 to 17 years of age) with lower...

Baclofen
https://www.ncbi.nlm.nih.gov/books/NBK526037/

Dec 15th, 2018 - Baclofen was originally designed in 1960 to treat epilepsy. However, the result was not satisfactory. Baclofen was then reintroduced in 1971 when it was found to treat muscle spasticity and has been widely used since. Baclofen is FDA-approved for ...

Medical Use of Cannabinoids
https://link.springer.com/article/10.1007/s40265-018-0996-1
Drugs Fraguas-Sánchez,A.,et al

Oct 28th, 2018 - Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocannabinoid system. In recent decades, the endocannabinoid system has attracted considerable interest as a potential ther...

Practice guideline update summary: Botulinum neurotoxin for the treatment of blepharosp...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862245
Neurology Simpson DM, Hallett M et. al.

May 10th, 2016 - To update the 2008 American Academy of Neurology (AAN) guidelines regarding botulinum neurotoxin for blepharospasm, cervical dystonia (CD), headache, and adult spasticity. We searched the literature for relevant articles and classified them using ...

Canadian stroke best practice recommendations: Stroke rehabilitation practice guideline...
https://doi.org/10.1177/1747493016643553
International Journal of Stroke : Official Journal of The... Hebert D, Lindsay MP et. al.

Apr 15th, 2016 - Stroke rehabilitation is a progressive, dynamic, goal-orientated process aimed at enabling a person with impairment to reach their optimal physical, cognitive, emotional, communicative, social and/or functional activity level. After a stroke, pati...

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Drugs  553 results see all →

Clinicaltrials.gov  7,009 results

Interventional Approaches to Pain and Spasticity Related to Cerebral Palsy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901135
Psychopharmacology Bulletin; Peck J, Urits I et. al.

Feb 26th, 2021 - This review will cover seminal and emerging evidence on interventional therapy chronic pain in cerebral palsy (CP). It will cover the background and burden of disease, present the current options, and then weigh the evidence that is available to s...

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic l...
https://doi.org/10.1080/15548627.2021.1891848
Autophagy Khundadze M, Ribaudo F et. al.

Feb 23rd, 2021 - Hereditary spastic paraplegia (HSP) denotes genetically heterogeneous disorders (SPGs) characterized by leg spasticity due to degeneration of corticospinal axons. SPG11 and SPG15 have a similar clinical course and together are the most prevalent a...

Early brain imaging predictors of post-stroke spasticity.
https://doi.org/10.2340/16501977-2803
Journal of Rehabilitation Medicine; Ri S, Glaess-Leistner S et. al.

Feb 22nd, 2021 - Post-stroke spasticity is a major factor disturbing rehabilitation and functional recovery in stroke survivors. Clinical predictors of post-stroke spasticity have often been discussed, but brain image predictors for spasticity have been insufficie...

Baclofen - baclofen tablet-A-S Medication Solutions
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=545a6bb2-d488-4057-a2ab-a5a53d23c9d6

Feb 22nd, 2021 - Baclofen is useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. Patients should have reversible spastic...

Longitudinal goal attainment with integrated upper limb spasticity management including...
https://doi.org/10.2340/16501977-2801
Journal of Rehabilitation Medicine; Turner-Stokes L, Jacinto J et. al.

Feb 22nd, 2021 - To assess the longitudinal effects of integrated spasticity management incorporating repeated cycles of botulinum toxin A type A (BoNT-A) over 2 years. The Upper Limb International Spasticity study was a prospective, observational, cohort study fo...

see more →

News  217 results

Fast Five Quiz: Multiple Sclerosis Presentation and Diagnosis
https://reference.medscape.com/viewarticle/924500

Jul 29th, 2020 - Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, leading to significant physical disability. The signs and symptoms of MS may include paresthesias, weakness, spasticity...

FDA Expands Dysport Use for Cerebral Palsy-Related Spasticity
https://www.staging.medscape.com/viewarticle/933891

Jul 13th, 2020 - The Food and Drug Administration has approved expanded use of Dysport to treat upper- and lower-limb spasticity – including that caused by cerebral palsy – for patients as young as 2 years and older, according to manufacturer Ipsen Biopharmaceutic...

FDA Expands Dysport Use for Cerebral Palsy-Related Spasticity
https://www.medscape.com/viewarticle/933891

Jul 13th, 2020 - The Food and Drug Administration has approved expanded use of Dysport to treat upper- and lower-limb spasticity – including that caused by cerebral palsy – for patients as young as 2 years and older, according to manufacturer Ipsen Biopharmaceutic...

Botulinum Toxin Reduces Chronic Pelvic Pain in Endometriosis
https://www.medscape.com/viewarticle/929990

May 4th, 2020 - Women with chronic pelvic pain (CPP) associated with endometriosis may benefit from an injection of botulinum toxin A (Botox, Allergan) without suffering significant adverse events, a new study suggests. Botulinum toxin has been used successfully ...

Fast Five Quiz: Cannabis Use and Abuse
https://reference.medscape.com/viewarticle/927888_2

Apr 7th, 2020 - Answer 1/5 Although further investigation is still needed, cannabis use currently has the strongest scientific support in treating which of the following? Your peers chose: Irritable bowel syndrome 0% Spasticity associated with multiple sclerosis ...

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Patient Education  5 results see all →