ALLMedicine™ Chorea Center

Jun 25th, 2022 - Pediatric primary antiphospholipid syndrome (APS) is a very rare disease with significant distinctions from the APS in adults. Herein, we present our experience in the diagnosis and treatment of six pediatric primary APS patients, who met the upda...

Jun 24th, 2022 - Investigators at National Institute of Allergy and Infectious Diseases (NIAID) are actively developing the infrastructure and capability for identifying the cause of heterogeneous immune-mediated disorders through whole exome and whole genome sequ...

Jun 22nd, 2022 - CP (cerebral palsy) refers to a group of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination. CP is caused by damage to or abnormalities inside the developing brain that dis...

Jun 21st, 2022 - Acute rheumatic fever is an autoimmune disease that develops due to streptococcal infection. The positive effect of breastfeeding on the development of the child's immune system is well documented. In this study, we aimed to investigate the effect...

Jun 21st, 2022 - Most reported patients carrying GNAO1 mutations showed a severe phenotype characterized by early-onset epileptic encephalopathy and/or chorea. The aim was to characterize the clinical and genetic features of patients with mild GNAO1-related phenot...

Aug 21st, 2010 - To develop recommendations for the diagnosis, prevention and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and pr...

Jun 24th, 2022 - Investigators at National Institute of Allergy and Infectious Diseases (NIAID) are actively developing the infrastructure and capability for identifying the cause of heterogeneous immune-mediated disorders through whole exome and whole genome sequ...

Jun 22nd, 2022 - CP (cerebral palsy) refers to a group of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination. CP is caused by damage to or abnormalities inside the developing brain that dis...

May 25th, 2022 - The occurrence of abnormal movements is a frequent reason for consultation in neurology. The etiologies are broadly separated into "primary causes", in example intrinsically neurological diseases (of genetic or degenerative origin), and "secondary...

Apr 11th, 2022 - This is a Phase 3, open-label study to evaluate the long-term safety and tolerability of valbenazine, and to provide subjects continued access to valbenazine for the treatment of chorea associated with Huntington disease.

Feb 22nd, 2022 - In the last decade, numerous studies have been published showing how epigenetic (environmental) factors can modify the clinical manifestations of diseases of genetic origin. Specifically, epidemiological studies have observed that physical exercis...

Apr 19th, 2022 - A drug currently approved for tardive dyskinesia (TD) is also effective at treating Huntington's disease (HD)–associated chorea, a movement disorder that affects most patients with HD, new phase 3 trial results show. Valbenazine is in the same cla...

Feb 18th, 2022 - LAS VEGAS – In the opinion of Christoph U. Correll, MD, tardive dyskinesia (TD) “has been somewhat forgotten” by psychiatrists because the risk of patients developing the condition is considered to be significantly lower with second-generation ant.

May 27th, 2020 - Initiation of saccadic movements is slow and uncoordinated, and smooth pursuit is interrupted by saccadic intrusions. Patients are unable to inhibit saccades toward a peripheral stimulus when instructed to look in the opposite direction. Eye movem...

May 27th, 2020 - Huntington disease (HD) is a genetic neurodegenerative disorder named after Dr George Huntington, who in 1872 reported his observations of dementia and chorea that ran in families on the East End of Long Island, New York. The disease is now known ...

May 27th, 2020 - The initial stages of Huntington disease are often characterized by deficits in short-term memory. This is frequently followed by motor dysfunction and a variety of cognitive changes, including diminished verbal fluency and problems with attention...