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About 1,423 results

ALLMedicine™ Chronic Traumatic Encephalopathy Center

Research & Reviews  434 results

Association of APOE Genotypes and Chronic Traumatic Encephalopathy.
https://doi.org/10.1001/jamaneurol.2022.1634
JAMA Neurology; Atherton K, Han X et. al.

Jun 28th, 2022 - Repetitive head impact (RHI) exposure is the chief risk factor for chronic traumatic encephalopathy (CTE). However, the occurrence and severity of CTE varies widely among those with similar RHI exposure. Limited evidence suggests that the APOEε4 a...

Chronic Traumatic Encephalopathy in the Brains of Military Personnel.
https://doi.org/10.1056/NEJMoa2203199
The New England Journal of Medicine; Priemer DS, Iacono D et. al.

Jun 9th, 2022 - Persistent neuropsychiatric sequelae may develop in military personnel who are exposed to combat; such sequelae have been attributed in some cases to chronic traumatic encephalopathy (CTE). Only limited data regarding CTE in the brains of military...

Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With an...
https://doi.org/10.1212/WNL.0000000000200678
Neurology Asken BM, Tanner JA et. al.

May 17th, 2022 - Traumatic encephalopathy syndrome (TES) has overlapping clinical symptoms with Alzheimer's disease (AD). AD pathology commonly co-occurs with chronic traumatic encephalopathy (CTE) pathology. There are currently no validated CTE biomarkers. AD-spe...

Prophylactic zinc supplementation modulates hippocampal ionic zinc and partially remedi...
https://doi.org/10.1016/j.bbr.2022.113918
Behavioural Brain Research; Neely CLC, Barkey RE et. al.

May 10th, 2022 - Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative condition caused by repetitive mild traumatic brain injury (TBI) that leads to impaired executive functioning, emotional disturbances, and disordered memory, warranting both...

Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome...
https://doi.org/10.1089/neu.2022.0060
Journal of Neurotrauma; Asken BM, Tanner JA et. al.

Apr 29th, 2022 - Traumatic encephalopathy syndrome (TES) criteria were developed to aid diagnosis of chronic traumatic encephalopathy (CTE) pathology during life. Interpreting clinical and biomarker findings in patients with TES during life necessitates autopsy-ba...

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Drugs  1 results see all →

Clinicaltrials.gov  18 results

The DIAGNOSE-CTE Research Project
https://clinicaltrials.gov/ct2/show/NCT02798185

Mar 8th, 2022 - Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease characterized by a distinct deposition of phosphorylated tau (p-tau) in neurons and astrocytes in a pattern that is unique from other tauopathies, including Alzheimer's disease ...

ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion
https://clinicaltrials.gov/ct2/show/NCT04744051

Feb 15th, 2022 - The proposed study is a single-site, double-blinded, placebo-controlled study involving a single administration of either individual, autologous ATCell™ lines suspended in 5% dextrose lactated Ringer's solution or a vehicle (5% dextrose Lactated R...

Long-term Follow-up in Severe Traumatic Brain Injury
https://clinicaltrials.gov/ct2/show/NCT05235802

Feb 11th, 2022 - The underlying pathophysiology following traumatic brain injury (TBI) in how different neurodegenerative conditions are developed are still unknown. Different neuroinflammatory and neurodegenerative pathways have been suggested. The goal of this s...

Prazosin and CSF Biomarkers in mTBI
https://clinicaltrials.gov/ct2/show/NCT03221751

Jan 24th, 2022 - Recruitment temporarily halted due to COVID-19 A majority of neurodegenerative dementing disorders, including Alzheimer's disease, (AD), dementia with Lewy bodies (DLB) and chronic traumatic encephalopathy (CTE), now appear to be caused by the acc...

Simvastatin for mTBI
https://clinicaltrials.gov/ct2/show/NCT01952288

Dec 15th, 2021 - Many Iraq and Afghanistan Veterans have experienced repetitive blast exposure mild traumatic brain injury (mTBI) with persistent cognitive, emotional, and neurological postconcussive symptoms. There is an urgent need to develop effective treatment...

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News  112 results

Tau Moderated by Menopause; CTE Risk Underestimated; When Is a Single Study Enough?
https://www.medpagetoday.com/neurology/generalneurology/98523

May 3rd, 2022 - Menopause status moderated sex differences in tau burden, with a divergence in tauopathy between the sexes apparent 20 years earlier than previously reported. (Annals of Neurology) Plasma p-tau was a less consistent marker of brain amyloidosis in ...

Tau Buildup in Brain Tied to Psychosis, More Rapid Decline in Alzheimer's Disease
https://www.medscape.com/viewarticle/970177

Mar 14th, 2022 - NEW YORK (Reuters Health) - Increased concentrations of the tau protein in the brain's frontal, medial and occipital cortices are associated with psychosis and more rapid cognitive and functional decline in Alzheimer's disease (AD) patients, an im...

NFL Players More Likely to Be Diagnosed With, Die of ALS
https://www.medpagetoday.com/neurology/generalneurology/96234

Dec 16th, 2021 - National Football League (NFL) players are over three times more likely to be diagnosed with and die from amyotrophic lateral sclerosis (ALS) compared with the general U.S. male population, according to a cohort study. Among over 19,000 former and...

Antibody Tx Fail; Omicron Cases Rise in the U.S.; NFL Mandates Boosters for Coaches
https://www.medpagetoday.com/infectiousdisease/covid19/96208

Dec 15th, 2021 - Adagio raised more than $750 million to develop a neutralizing antibody that would treat various forms of COVID, but its latest effort appears to be a bust against Omicron. (Endpoints News) The highly infectious variant now accounts for about 3% o...

MRI Key to Diagnosing CTE in Living Patients?
https://www.medscape.com/viewarticle/964345

Dec 7th, 2021 - A distinct pattern of frontal-temporal atrophy discernible on magnetic resonance imaging (MRI) may flag chronic traumatic encephalopathy (CTE) in living patients, new research suggests. Dr Michael L. Alosco "These new results offer some hope for c...

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Patient Education  4 results see all →