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About 3,260 results

ALLMedicine™ Essential Tremor Center

Research & Reviews  1,128 results

Clinical and Physiological Studies of Tremor Syndromes
https://clinicaltrials.gov/ct2/show/NCT03027310

Jan 14th, 2022 - Objectives The purpose of this protocol is to study the phenotypic spectrum and the pathophysiology of tremor syndromes by performing small behavioral, electrophysiological and neuroimaging sub-studies. The protocol includes techniques with minima...

Deep Brain Stimulation Surgery for Movement Disorders
https://clinicaltrials.gov/ct2/show/NCT01581580

Jan 12th, 2022 - Objective: The objective of this protocol is to provide DBS surgery and to collect physiology and efficacy data related to DBS therapy and motor and cognitive function in people with medically refractory Parkinson s disease (PD), dystonia, and ess...

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study a...
https://doi.org/10.1001/jamaneurol.2021.4781
JAMA Neurology; Liao C, Castonguay CE et. al.

Jan 5th, 2022 - Essential tremor (ET) is one of the most common movement disorders, affecting 5% of the general population older than 65 years. Common variants are thought to contribute toward susceptibility to ET, but no variants have been robustly identified. T...

Tremor associated with similar structural networks in Parkinson's disease and essential...
https://doi.org/10.1016/j.parkreldis.2021.12.014
Parkinsonism & Related Disorders; Filip P, Burdová K et. al.

Jan 4th, 2022 - Despite substantial clinical and pathophysiological differences, the characteristics of tremor in Parkinson's disease (PD) and essential tremor (ET) patients bear certain similarities. The presented study delineates tremor-related structural netwo...

Intraoperative lesion characterization after focused ultrasound thalamotomy.
https://doi.org/10.3171/2021.10.JNS211651
Journal of Neurosurgery; Sammartino F, Yeh FC et. al.

Jan 1st, 2022 - Outcomes after focused ultrasound ablation (FUSA) for essential tremor remain heterogeneous, despite therapeutic promise. Clinical outcomes are directly related to the volume and location of the therapeutic lesions, consistent with CNS ablative th...

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Drugs  32 results see all →

Clinicaltrials.gov  59 results

Clinical and Physiological Studies of Tremor Syndromes
https://clinicaltrials.gov/ct2/show/NCT03027310

Jan 14th, 2022 - Objectives The purpose of this protocol is to study the phenotypic spectrum and the pathophysiology of tremor syndromes by performing small behavioral, electrophysiological and neuroimaging sub-studies. The protocol includes techniques with minima...

Deep Brain Stimulation Surgery for Movement Disorders
https://clinicaltrials.gov/ct2/show/NCT01581580

Jan 12th, 2022 - Objective: The objective of this protocol is to provide DBS surgery and to collect physiology and efficacy data related to DBS therapy and motor and cognitive function in people with medically refractory Parkinson s disease (PD), dystonia, and ess...

Motor Network Physiology
https://clinicaltrials.gov/ct2/show/NCT04957095

Dec 29th, 2021 - The brain networks controlling movement are complex, involving multiple areas of the brain. Some neurological disorders, like Parkinson's disease (PD) and essential tremor (ET), cause abnormalities in these brain networks. Deep brain stimulation i...

A Clinical Trial of 3 Doses of PRAX-944 in Participants With Essential Tremor
https://clinicaltrials.gov/ct2/show/NCT05021991

Dec 6th, 2021 - This is a randomized, double-blind, placebo-controlled clinical trial to evaluate the tolerability, safety, and efficacy of 20, 60, and 120 mg oral PRAX-944 compared to placebo in the treatment of adults with essential tremor. Blood levels of PRAX...

Bilateral Essential Tremor Treatment With Gamma Knife
https://clinicaltrials.gov/ct2/show/NCT04748640

Nov 17th, 2021 - Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for essential tremor will undergo a contralateral treatment. The i...

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News  79 results

Genetic Variations Explain Essential Tremor Risk
https://www.medscape.com/viewarticle/966553

Jan 13th, 2022 - Several common regions of DNA are linked to an increased risk of developing essential tremor (ET), new research shows. Investigators studied more than 480,000 adults and found five genetic loci that were significantly associated with ET risk, part...

Focused Ultrasound Approved for Advanced Parkinson's
https://www.medpagetoday.com/neurology/parkinsonsdisease/95458

Nov 5th, 2021 - The FDA expanded the approval of Exablate Neuro focused ultrasound to treat advanced Parkinson's disease patients with mobility, rigidity, or dyskinesia symptoms, device maker Insightec announced Wednesday. With this new indication, Exablate Neuro...

Novel Drug Effective for Essential Tremor, but With Significant Side Effects
https://www.medscape.com/viewarticle/959811

Sep 27th, 2021 - The investigational oral, neuroactive, steroid-positive allosteric modulator SAGE-324/BIIB124 (SAGE-324) is effective for treating essential tremor ― but problems with tolerability may limit its usefulness, new research suggests. The phase 2 KINET...

Low-Intensity Focused Ultrasound Safe, Effective in Mild Alzheimer's Disease
https://www.medscape.com/viewarticle/957487

Aug 30th, 2021 - A new noninvasive procedure is safe and effective for treating patients with mild Alzheimer's disease (AD), new research suggests. Clinicians monitor a trial patient with AD undergoing low-intensity focused ultrasound. The approach uses MRI-guided...

FDA Clears Next-Generation DBS System for Movement Disorders
https://www.medscape.com/viewarticle/952660

Jun 8th, 2021 - The US Food and Drug Administration (FDA) has approved Medtronic's technologically advanced deep brain stimulation (DBS) system designed to more precisely target motor symptoms in Parkinson's disease, dystonia, or essential tremor. The SenSight Di...

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Patient Education  6 results see all →