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About 12,815 results

ALLMedicine™ Spasticity Center

Research & Reviews  3,617 results

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
https://clinicaltrials.gov/ct2/show/NCT04984278

Jul 1st, 2022 - Each period of this multicenter, randomized, double-blind, placebo-controlled, 2-treatment, 2-period, crossover trial includes a 7-day Baseline period, a 3-week treatment period (comprising a 2-week titration phase and a 1-week maintenance phase)....

Human Movement Database
https://clinicaltrials.gov/ct2/show/NCT00001252

Jul 1st, 2022 - The purpose of this study is to develop a database of normative and adaptive control strategies for human motion. Volunteers will serve as subjects after they complete a neuromusculoskeletal screening exam. Subjects will be asked to perform one or...

Phenotypic Description of Patients With Atypical Clinical Forms of PLA2G6 Mutations
https://clinicaltrials.gov/ct2/show/NCT05440994

Jul 1st, 2022 - Patients with biallelic mutations in PLA2G6 with an atypic INAD starting before 18 years will be recruited after a collaboration call of neuropaediatricians in France. After family consent, a retrospective collection of data will be performed usin...

Effects of Dry Needling on Connectivity of Corticospinal Tract, Spasticity, and Functio...
https://doi.org/10.51507/j.jams.2021.14.6.238
Journal of Acupuncture and Meridian Studies; Ebrahimzadeh M, Ansari NN et. al.

Jul 1st, 2022 - Spasticity is a common motor disorder in adult stroke patients. Injury to the corticospinal tract (CST) is associated with spasticity. Dry needling (DN) has positive impacts on spasticity reduction and improvement in the range of motion (ROM) in s...

Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
https://clinicaltrials.gov/ct2/show/NCT04657666

Jun 30th, 2022 - Each period of this multicenter, randomized, double-blind, placebo-controlled, 2-treatment, 2-period, crossover trial includes a 7-day Baseline period, a 3-week treatment period (comprising a 2-week titration phase and a 1-week maintenance phase)....

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Guidelines  6 results

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on th...
https://doi.org/10.1093/neuros/nyy370
Neurosurgery Harrop JS, Chi JH et. al.

Sep 12th, 2018 - Which neurological assessment tools have demonstrated internal reliability and validity in the management of patients with thoracic and lumbar fractures (ie, do these instruments provide consistent information between different care providers)? Nu...

Canadian stroke best practice recommendations: Stroke rehabilitation practice guideline...
https://doi.org/10.1177/1747493016643553
International Journal of Stroke : Official Journal of The... Hebert D, Lindsay MP et. al.

Apr 16th, 2016 - Stroke rehabilitation is a progressive, dynamic, goal-orientated process aimed at enabling a person with impairment to reach their optimal physical, cognitive, emotional, communicative, social and/or functional activity level. After a stroke, pati...

Spasticity in children and young people with non-progressive brain disorders: summary o...
https://doi.org/10.1136/bmj.e4845
BMJ (Clinical Research Ed.); Mugglestone MA, Eunson P et. al.

Jul 28th, 2012 - Spasticity in children and young people with non-progressive brain disorders: summary of NICE guidance.|2012|Mugglestone MA,Eunson P,Murphy MS, ,|administration & dosage,administration & dosage,complications,epidemiology,complications,therapeutic ...

Botulinum toxin assessment, intervention and after-care for lower limb spasticity in ch...
https://doi.org/10.1111/j.1468-1331.2010.03126.x
European Journal of Neurology; Love SC, Novak I et. al.

Jul 17th, 2010 - Botulinum neurotoxin type-A (BoNT-A) has been used in association with other interventions in the management of spasticity in children with cerebral palsy (CP) for almost two decades. This consensus statement is based on an extensive review of the...

Botulinum toxin assessment, intervention and after-care for upper limb hypertonicity in...
https://doi.org/10.1111/j.1468-1331.2010.03129.x
European Journal of Neurology; Sheean G, Lannin NA et. al.

Jul 17th, 2010 - Upper limb spasticity affecting elbow, wrist, and finger flexors can be safely and effectively reduced with injections of botulinum toxin type-A (BoNT-A). It has been best studied in adults in the context of post-stroke spasticity. The clinical be...

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Drugs  424 results see all →

Clinicaltrials.gov  843 results

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
https://clinicaltrials.gov/ct2/show/NCT04984278

Jul 1st, 2022 - Each period of this multicenter, randomized, double-blind, placebo-controlled, 2-treatment, 2-period, crossover trial includes a 7-day Baseline period, a 3-week treatment period (comprising a 2-week titration phase and a 1-week maintenance phase)....

Human Movement Database
https://clinicaltrials.gov/ct2/show/NCT00001252

Jul 1st, 2022 - The purpose of this study is to develop a database of normative and adaptive control strategies for human motion. Volunteers will serve as subjects after they complete a neuromusculoskeletal screening exam. Subjects will be asked to perform one or...

Phenotypic Description of Patients With Atypical Clinical Forms of PLA2G6 Mutations
https://clinicaltrials.gov/ct2/show/NCT05440994

Jul 1st, 2022 - Patients with biallelic mutations in PLA2G6 with an atypic INAD starting before 18 years will be recruited after a collaboration call of neuropaediatricians in France. After family consent, a retrospective collection of data will be performed usin...

Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
https://clinicaltrials.gov/ct2/show/NCT04657666

Jun 30th, 2022 - Each period of this multicenter, randomized, double-blind, placebo-controlled, 2-treatment, 2-period, crossover trial includes a 7-day Baseline period, a 3-week treatment period (comprising a 2-week titration phase and a 1-week maintenance phase)....

Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin
https://clinicaltrials.gov/ct2/show/NCT05103202

Jun 30th, 2022 - Our project has the following aims: Aim 1: to determine if any difference exists in safety or efficacy between patients receiving injections of botulinum toxin at 10-week or shorter intervals as compared to patients receiving injections at 12-week...

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News  224 results

Restless Legs Syndrome Common in X-linked Adrenoleukodystrophy
https://www.medscape.com/viewarticle/971868

Apr 8th, 2022 - Restless legs syndrome occurred in approximately 40% of adults with X-linked adrenoleukodystrophy, based on data from 32 individuals. Dr John Winkelman Patients with X-linked adrenoleukodystrophy (ALD), a neurodegenerative disease, often experienc...

ACTRIMS 2022: Updates in Multiple Sclerosis Symptom Management
https://www.mdedge.com/neurology/article/253055/conference-recap/actrims-2022-updates-multiple-sclerosis-symptom-management
Enrique Alvarez, MD, PhD

Mar 22nd, 2022 - Dr Enrique Alvarez, Associate Professor at the University of Colorado, reviews updates in symptom management that were presented at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) 2022 meeting. First, Dr Alvarez h.

Botulinum toxin for chronic pain: What's on the horizon?
https://www.mdedge.com/familymedicine/article/248633/musculoskeletal-disorders/botulinum-toxin-chronic-pain-whats-horizon
MDedge Family Medicine; Caleb Dickison, DO, CAQSM, Jeffrey C. Leggit, MD, CAQSM

Nov 12th, 2021 - Botulinum toxin (BoNT) was first approved by the US Food and Drug Administration (FDA) for the treatment of strabismus and blepharospasm in 1989. Since then, approved indications have expanded to include spasticity, cervical dystonia, severe axill.

Cannabis Use Common for MS-Related Spasticity
https://www.medscape.com/viewarticle/961912

Oct 29th, 2021 - ORLANDO, Florida — Use of cannabis is common in patients with multiple sclerosis (MS), especially for the treatment of MS-related spasticity, new research suggests. Findings from a survey conducted through a large registry in 2020 showed that 31% ...

Pain in MS: Focus on flexibility, multiple strategies, and nondrug treatments
https://www.mdedge.com/neurology/article/247958/multiple-sclerosis/pain-ms-focus-flexibility-multiple-strategies-and
Randy Dotinga

Oct 27th, 2021 - Pain is as individual as patients are, a multiple sclerosis (MS) specialist told colleagues, and one size does not fit all when it comes to treatment. Flexibility and multiple strategies are key, especially considering that pain can evolve over ti.

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Patient Education  12 results see all →