ALLMedicine™ Brain Metastasis Center

Feb 25th, 2021 - Immune checkpoint inhibitors (ICI) have been a breakthrough for selected cancer patients, including those with brain metastases (BMs). Likewise, steroids have been an integral component of symptomatic management of BM patients. However, clinical e...

Feb 24th, 2021 - Prostate cancer is rarely metastatic to visceral organs, and even less commonly to the brain. Recent data suggests brain metastasis from prostatic adenocarcinoma occur in 0.16% of patients, and almost universally in the setting of very high-volume...

Feb 22nd, 2021 - Metastatic spread to the brain is a common and devastating manifestation of many types of cancer. In the United States alone, about 200,000 patients are diagnosed with brain metastases each year. Significant progress has been made in improving sur...

Feb 17th, 2021 - Radiotherapy is the mainstay of brain metastasis (BM) management. Radiation necrosis (RN) is a serious complication of radiotherapy. Bevacizumab (BV), an anti-vascular endothelial growth factor monoclonal antibody, has been increasingly used for R...

Feb 15th, 2021 - Lung cancer is the most frequent cause of cancer-related death worldwide and is usually diagnosed in advanced stages. Among those, approximately 7.4% of non-small cell lung cancer (NSCLC) patients will have brain metastasis (BM) at presentation, a...

Jan 8th, 2019 - This series of guidelines was constructed to assess the most current and clinically relevant evidence for management of metastatic brain tumors. They set a benchmark regarding the current evidence base for this management while also highlighting i...

Jun 24th, 2018 - Patients with brain metastases should receive appropriate local therapy and systemic therapy, if indicated. Local therapies include surgery, whole-brain radiotherapy, and stereotactic radiosurgery. Treatments depend on factors such as patient prog...

Feb 14th, 2018 - Previous studies have demonstrated the association between EGFR mutations and distant metastasis. However, the association for subsequent brain metastasis (BM) in stages I-III non-small cell lung cancer (NSCLC) patients remains inconclusive. We co...

Apr 16th, 2017 - To systematically review the evidence for the radiotherapeutic and surgical management of patients newly diagnosed with intraparenchymal brain metastases.

Jun 30th, 2014 - To provide formal expert consensus–based recommendations to practicing oncologists and others on the management of brain metastases for patients with human epidermal growth factor receptor 2 (HER2) –positive advanced breast cancer.

Feb 25th, 2021 - Immune checkpoint inhibitors (ICI) have been a breakthrough for selected cancer patients, including those with brain metastases (BMs). Likewise, steroids have been an integral component of symptomatic management of BM patients. However, clinical e...

Feb 24th, 2021 - Prostate cancer is rarely metastatic to visceral organs, and even less commonly to the brain. Recent data suggests brain metastasis from prostatic adenocarcinoma occur in 0.16% of patients, and almost universally in the setting of very high-volume...

Feb 22nd, 2021 - Metastatic spread to the brain is a common and devastating manifestation of many types of cancer. In the United States alone, about 200,000 patients are diagnosed with brain metastases each year. Significant progress has been made in improving sur...

Feb 17th, 2021 - Radiotherapy is the mainstay of brain metastasis (BM) management. Radiation necrosis (RN) is a serious complication of radiotherapy. Bevacizumab (BV), an anti-vascular endothelial growth factor monoclonal antibody, has been increasingly used for R...

Feb 15th, 2021 - Lung cancer is the most frequent cause of cancer-related death worldwide and is usually diagnosed in advanced stages. Among those, approximately 7.4% of non-small cell lung cancer (NSCLC) patients will have brain metastasis (BM) at presentation, a...

Oct 27th, 2020 - Stereotactic radiosurgery (SRS) should replace whole-brain radiotherapy (WBRT) as the new standard of care for patients with four or more brain metastases, say researchers who report results from a randomized trial conducted in patients with four ...

May 20th, 2019 - Discussion The CT findings of a mass with associated edema, along with his history of lung cancer, strongly suggested brain metastasis (Figure 1). (Enlarge Image) Figure 1. In this case, a solitary metastasis must be differentiated from a primary ...

May 15th, 2019 - Younger patients with non–small cell lung cancer (NSCLC) may have better survival, despite higher rates of brain metastasis and driver mutations, according to results from a retrospective analysis. “We carried out a comprehensive analysis of patie.

Mar 17th, 2019 - A comprehensive literature review of brain metastasis in brain cancer found that the most common symptoms included headache (35%), vomiting (26%), nausea (23%), hemiparesis (22%), visual changes (13%), and seizures (12%). Other symptoms associated...

Mar 13th, 2019 - This transcript has been edited for clarity. Hello. This is Mark Kris from Memorial Sloan Kettering (MSK), talking today about a common and difficult problem both for patients and practitioners, and that is the treatment of brain metastases. I'm g...