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About 5,278 results

ALLMedicine™ Brain Metastasis Center

Research & Reviews  1,715 results

Surgical efficacy and prognosis of 54 cases of spinal metastases from breast cancer.
https://doi.org/10.1016/j.wneu.2022.06.060
World Neurosurgery; Weitao Y, Zhihuang L et. al.

Jun 25th, 2022 - To analyze the efficacy and complications of spinal metastasis surgery for breast cancer; to understand the survival and the influencing factors; and to verify the predictive ability of the currently used spinal metastasis cancer survival predicti...

NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis
https://clinicaltrials.gov/ct2/show/NCT04129515

Jun 24th, 2022 - The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits. The name of the study device involved in this study is: NovoTTF-200A The name of the drug used in this study is: Pembro...

Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT01445483

Jun 24th, 2022 - Background: Metastatic brain tumors occur more frequently than primary brain tumors and occur in approximately 25 percent of patients who die of cancer each year. The Radiation Therapy Oncology Group (RTOG) developed three prognostic classes using...

Retrospective Analysis of Emotional Burden and the Need for Support of Patients and The...
https://doi.org/10.3390/curroncol29060338
Current Oncology (Toronto, Ont.); Lütscher J, Siegenthaler CH et. al.

Jun 24th, 2022 - Cancer burdens not only the patients themselves but also their personal environment. A few studies have already focused on the mental health and personal needs of caregivers of patients. The purpose of this retrospective analysis was to further as...

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Guidelines  2 results

EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patien...
https://doi.org/10.1016/j.annonc.2021.07.016
Annals of Oncology : Official Journal of the European Soc... Le Rhun E, Guckenberger M et. al.

Aug 9th, 2021 - EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours.|2021|Le Rhun E,Guckenberger M,Smits M,Dummer R,Bachelot T,|diagnosis,therapy,

A Cancer Care Ontario Organizational Guideline for the Delivery of Stereotactic Radiosu...
https://doi.org/10.1016/j.prro.2019.11.002
Practical Radiation Oncology; Sahgal A, Kellett S et. al.

Nov 30th, 2019 - In Ontario, Canada, there is increasing demand for stereotactic radiosurgery (SRS) for brain metastases. Recommendations for safe SRS delivery are needed to ensure that patients receive an equitable level of care across the province. This guidelin...

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Clinicaltrials.gov  233 results

Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT01445483

Jun 24th, 2022 - Background: Metastatic brain tumors occur more frequently than primary brain tumors and occur in approximately 25 percent of patients who die of cancer each year. The Radiation Therapy Oncology Group (RTOG) developed three prognostic classes using...

NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis
https://clinicaltrials.gov/ct2/show/NCT04129515

Jun 24th, 2022 - The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits. The name of the study device involved in this study is: NovoTTF-200A The name of the drug used in this study is: Pembro...

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).
https://clinicaltrials.gov/ct2/show/NCT02831959

Jun 23rd, 2022 - PAST PRE-CLINICAL AND CLINICAL EXPERIENCE: The effect of the electric fields (TTFields, TTF) has demonstrated significant activity in in vitro and in vivo NSCLC pre-clinical models both as a single modality treatment and in combination with chemot...

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
https://clinicaltrials.gov/ct2/show/NCT04739761

Jun 23rd, 2022 - Approximately 500 eligible participants will be enrolled into 1 of 2 cohorts (250 participants in each cohort) according to the presence or absence of BMs at baseline. Cohort 1 will include participants without BM at baseline and Cohort 2 will con...

Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT05428852

Jun 23rd, 2022 - Neurological tissues are among the most common (>10% of cancer patients) and debilitating sites for metastatic disease to develop. The brain is a 'sanctuary site' for many cancer cells and remains a challenging site to treat. Surgery and radiation...

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News  161 results

ALK+ advanced NSCLC with brain mets: Lorlatinib boosts PFS, reduces CNS progression
https://www.mdedge.com/hematology-oncology/article/255649/lung-cancer/alk-advanced-nsclc-brain-mets-lorlatinib-boosts-pfs

Jun 22nd, 2022 - Key clinical point : Lorlatinib extends progression-free survival (PFS) and reduces central nervous system (CNS) progression compared with crizotinib in patients with anaplastic lymphoma kinase positive ( ALK+) advanced nonsmall cell lung cancer (.

ASCO 2022: An Abundance of Data for the Field of Melanoma
https://www.medscape.com/viewarticle/975371

Jun 22nd, 2022 - Michael Postow, MD, offers an immediate reflection on compelling data surrounding adjuvant and neoadjuvant treatments for melanoma, as well as other items of clinical interest, presented at the ASCO 2022 conference. An update on the KEYNOTE-716 tr...

NSCLC with brain metastasis: ICI-radiotherapy combo prolongs OS vs chemoradiotherapy
https://www.mdedge.com/hematology-oncology/article/254927/lung-cancer/nsclc-brain-metastasis-ici-radiotherapy-combo

May 24th, 2022 - Key clinical point : Immune checkpoint inhibitors (ICI) plus radiotherapy (RT) conferred an overall survival (OS) benefit over chemotherapy plus RT after resection of brain metastasis from non-small cell lung cancer (NSCLC). Major finding : The ch.

Prognostic factors in male breast cancer with bone metastases
https://www.mdedge.com/hematology-oncology/article/254754/breast-cancer/prognostic-factors-male-breast-cancer-bone

May 18th, 2022 - Key clinical point: Age, tumor subtype, surgery, and brain metastasis are independent risk factors for survival in male patients with breast cancer (BC) and bone metastases and should be considered when devising a treatment strategy. Major finding.

Overcoming Resistance to Radiotherapy for Brain Metastases
https://www.medscape.com/viewarticle/972501

Apr 21st, 2022 - Researchers have identified a new strategy that can help pinpoint which patients with brain metastasis may be resistant to whole brain radiation therapy (WBRT), and they have also identified a potential therapeutic option. A Spanish team has found...

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