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About 5,890 results

ALLMedicine™ Meningioma Center

Research & Reviews  2,268 results

Human endogenous retrovirus type K promotes proliferation and confers sensitivity to an...
https://doi.org/10.1158/0008-5472.CAN-20-3857
Cancer Research; Maze EA, Agit B et. al.

Dec 3rd, 2021 - Deficiency of the tumour suppressor Merlin causes development of schwannoma, meningioma, and ependymoma tumours, which can occur spontaneously or in the hereditary disease neurofibromatosis type 2 (NF2). Merlin mutations are also relevant in a var...

Intracranial venous malformation masquerading as a meningioma in PI3KCA-related overgro...
https://doi.org/10.1002/ajmg.a.62570
American Journal of Medical Genetics. Part A; Filippidis A, Lidov H et. al.

Dec 3rd, 2021 - Gain of function PIK3CA pathogenic variants have been identified in overgrowth syndromes collectively termed "PIK3CA-related overgrowth spectrum" (PROS). There are no previously reported cases of cerebrovascular venous malformations in PROS syndro...

Tumor-Derived Cell Culture Model for the Investigation of Meningioma Biology.
https://doi.org/10.1093/jnen/nlab111
Journal of Neuropathology and Experimental Neurology; Uhlmann EJ, Rabinovsky R et. al.

Dec 2nd, 2021 - Meningioma is the most common primary central nervous system tumor. Although mostly nonmalignant, meningioma can cause serious complications by mass effect and vasogenic edema. While surgery and radiation improve outcomes, not all cases can be tre...

Eribulin prolongs survival in an orthotopic xenograft mouse model of malignant meningioma.
https://doi.org/10.1111/cas.15221
Cancer Science; Nakano T, Fujimoto K et. al.

Nov 29th, 2021 - Meningioma is the most common intracranial tumor, with generally favorable patient prognosis. However, patients with malignant meningioma typically experience recurrence, undergo multiple surgical resections, and ultimately have a poor prognosis. ...

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Guidelines  1 results

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: Intern...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566438
Neurosurgery Marchetti M, Sahgal A et. al.

May 29th, 2020 - Stereotactic radiosurgery (SRS) for benign intracranial meningiomas is an established treatment. To summarize the literature and provide evidence-based practice guidelines on behalf of the International Stereotactic Radiosurgery Society (ISRS). Ar...

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Clinicaltrials.gov  30 results

Gleolan for Visualization of Newly Diagnosed or Recurrent Meningioma
https://clinicaltrials.gov/ct2/show/NCT04305470

Nov 15th, 2021 - This Phase 3 open-label single-arm study is designed to investigate the safety, diagnostic performance, and clinical usefulness of the imaging agent Gleolan™ (Aminolevulinic Acid Hydrochloride, ALA HCl, ALA, 5-ALA), an orally administered imaging ...

Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas.
https://clinicaltrials.gov/ct2/show/NCT05081908

Oct 18th, 2021 - Meningioma is the most common intracranial tumor (1). World Health Organization (WHO) grade II (atypical) meningioma recurs more frequently than WHO grade I (benign) meningioma, and patients with subtotally resected atypical meningioma should be t...

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
https://clinicaltrials.gov/ct2/show/NCT02523014

Oct 12th, 2021 - PRIMARY OBJECTIVES: I. To determine the activity of a SMO inhibitor in patients with meningiomas harboring SMO and PTCH1 mutations as measured by 6-month progression free survival (PFS) and response rate. II. To determine the activity of a FAK inh...

Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study
https://clinicaltrials.gov/ct2/show/NCT04372095

Oct 4th, 2021 - The increased risk to develop a meningioma has recently been established for patients received the cyproterone acetate. The investigators observed several familial cases of CPA related meningiomas which suggest a strong genetic factor modulating t...

Concordance and Accuracy of MRI in the Detection of Meningiomas: Optimizing Sequences With Low Doses of Gadolinium
https://clinicaltrials.gov/ct2/show/NCT04113395

Sep 17th, 2021 - Meningioma, an extra-axial brain tumor developed at the expense of meninges, accounts for 35% of central nervous system tumors, and its incidence is estimated at 3% in large autopsy series. The current gold standard for screening and monitoring ce...

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News  49 results

GI Cancer and Obesity: Fighting One Means Addressing the Other
https://www.medscape.com/viewarticle/959973

Oct 6th, 2021 - By 2030, it is projected that most Americans will be overweight, and of those, nearly 50% of adults will be obese. Although the majority of Americans are aware that obesity can have adverse health consequences, survey findings show that few are aw...

cfMeDIP-seq Provides Opportunity for Early Cancer Detection, Classification, and Monitoring
https://www.onclive.com/view/cfmedip-seq-provides-opportunity-for-early-cancer-detection-classification-and-monitoring

May 19th, 2021 - Cell-free methylated DNA immunoprecipitation-sequencing (cfMeDIP-seq) uses plasma cell-free methylomes to detect and classify several types of cancer early on, and provides the opportunity to monitor tumors for response to treatment in noninvasive...

Novel Treatments in Glioblastoma: Looking Ahead
https://www.onclive.com/view/novel-treatments-in-glioblastoma-looking-ahead

Apr 2nd, 2021 - Transcript:Steven A. Toms, MD: What is the future of a device like Optune? It seems to be a fairly basic mechanism in cancer that may be used in other areas. Certainly, I know that there are trials going on in Europe right now for lung, ovarian, a...

Increased Risk of Meningioma With Cyproterone Acetate Use
https://www.medscape.com/viewarticle/945218

Feb 3rd, 2021 - New details confirm an increased risk of developing intracranial meningiomas after prolonged use of the hormonal product cyproterone acetate. Cyproterone acetate is a synthetic progestogen and potent anti-androgen that has been used in the treatme...

Optimizing Precision Medicine Approaches in Glioblastoma
https://www.onclive.com/view/optimizing-precision-medicine-approaches-in-glioblastoma

Dec 20th, 2020 - Mark R. Gilbert, MD The deployment of precision medicine to develop safe and effective therapies to treat malignant brain tumors is an endeavor eagerly embraced by researchers and patients alike, but the effort poses both opportunities and challe...

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Patient Education  8 results see all →