ALLMedicine™ Paraneoplastic Syndromes Center

Jan 15th, 2022 - A 41-year-old female presented with dysgeusia, dry eyes, nyctalopia with progressive visual field constriction (due to autoimmune retinopathy) and gastrointestinal symptoms (due to ulcerative colitis). She was subsequently admitted to intensive ca...

Nov 20th, 2021 - History Renal cell carcinoma (RCC) may remain clinically occult for most of its course. The classic triad of flank pain, hematuria, and flank mass is uncommon (10%) and is indicative of advanced disease. Twenty-five to thirty percent of patients a...

Nov 20th, 2021 - Approach Considerations With the increasing utilization of imaging studies, renal cell carcinoma (RCC) is increasingly detected incidentally, as a suspicious mass on abdominal computed tomography (CT) or ultrasound. [17] Fewer patients present wit...

Nov 20th, 2021 - History Renal cell carcinoma (RCC) may remain clinically occult for most of its course. The classic triad of flank pain, hematuria, and flank mass is uncommon (10%) and is indicative of advanced disease. Twenty-five to thirty percent of patients a...

Nov 9th, 2021 - Practice Essentials Hodgkin lymphoma is a potentially curable lymphoma. The World Health Organization classifies Hodgkin lymphoma into the following types [1, 2] : Nodular sclerosing Mixed cellularity (see the image below) Lymphocyte depleted Lymp...

Dec 21st, 2021 - David Gerber, MD: Steve, it might be helpful at this point to go over how we diagnose and test for LEMS [Lambert-Eaton myasthenic syndrome]. Steven Vernino, MD, PhD: As neurologists, when we see conditions that make us think about paraneoplastic ...

Jul 20th, 2021 - Hossein Borghaei, DO, MS: What do you use in your clinic? How do you choose who can get immunotherapy? Is there a patient in whom you know you’re not going to offer immunotherapy to? Can you go through your working diagnosis and everything else wh...

Apr 2nd, 2021 - Suresh Ramalingam, MD: Where does PD-L1 expression stand in small-cell lung cancer? Is this something you test in your routine clinic? Martin, let me ask you that question and then have Christine chime in as well. Martin Dietrich, MD, PhD: That...

Apr 2nd, 2021 - For High-Definition, Click The effectiveness of cytoreductive nephrectomy as a standard of care for untreated patients with metastatic renal cell carcinoma (mRCC) has been drawn into question with the introduction of targeted therapies. In some ...

Apr 2nd, 2021 - Transcript: Mark A. Socinski, MD: Let’s switch gears. Corey said before that it’s been 25 years. I don’t know if it’s that much that we haven’t made progress in stage III. Chemoradiotherapy. Let’s talk about small cell lung cancer. I think tha...