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About 15,006 results

ALLMedicine™ Status Epilepticus Center

Research & Reviews  7,217 results

The Kv7 modulator, retigabine, is an efficacious antiseizure drug for delayed treatment...
https://doi.org/10.1016/j.neuroscience.2021.03.029
Neuroscience Barker BS, Spampanato J et. al.

Apr 9th, 2021 - Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant ...

Hippocampal and septal 5-HT1A receptor expression in two rat models of temporal lobe ep...
https://doi.org/10.1016/j.neuroscience.2021.03.026
Neuroscience Schönhoff K, von Rüden EL et. al.

Apr 9th, 2021 - Experimental and clinical data suggest an impact of serotonergic signaling on seizure susceptibility and epilepsy-associated psychiatric comorbidities. Previous µPET studies revealed increased binding of 5-HT1A receptor ligand [18F]MPPF in two rat...

Pharmacotherapy for Nonconvulsive Seizures and Nonconvulsive Status Epilepticus.
https://doi.org/10.1007/s40265-021-01502-4 10.1111/epi.13121 10.1001/archneur.1973.00490190019001 10.1001/archneur.1973.00490190028002 10.1001/archneur.1973.00490260026003 10.1111/j.1528-1157.1988.tb04226.x 10.1001/jama.1993.03510070076040 10.1056/NEJM199809173391202 10.1111/j.1528-1157.1999.tb02070.x 10.1002/ana.1018 10.1212/WNL.58.4.537 10.1136/jnnp.74.2.189 10.1097/01.nrl.0000162954.76053.d2 10.1016/S1474-4422(07)70074-1 10.1016/j.clinph.2017.01.015 10.1111/j.1528-1157.1998.tb01177.x 10.1212/WNL.46.4.1029 10.1212/WNL.50.3.735 10.1212/WNL.54.2.340 10.1046/j.1528-1157.2001.0420081031.x 10.1111/j.1528-1167.2005.00409.x 10.1007/s12028-013-9935-x 10.1038/nrneurol.2015.104 10.1111/epi.16277 10.1016/j.seizure.2004.06.001 10.1016/j.seizure.2013.08.003 10.1016/0920-1211(94)90062-0 10.1016/j.yebeh.2003.11.032 10.1111/j.1528-1157.1993.tb02123.x 10.1002/ana.410180303 10.1124/jpet.104.069146 10.1111/epi.14070 10.1001/archneur.55.1.119 10.1001/archneur.55.1.117 10.1212/WNL.47.1.83 10.1016/S0920-1211(97)00071-5 10.1212/WNL.52.4.746 10.1212/01.WNL.0000063316.47591.B4 10.1097/01.CCM.0000295667.66853.BC 10.1212/WNL.0b013e3181f07334 10.1212/WNL.0b013e31829c5cfe 10.1093/brain/awu042 10.1212/WNL.0000000000000082 10.1212/WNL.0000000000002281 10.1002/ana.24606 10.1001/jamaneurol.2016.5325 10.1016/j.clinph.2018.08.015 10.1007/s12028-020-00944-0 10.1523/JNEUROSCI.17-19-07532.1997 10.1056/NEJMoa002141 10.1186/1865-1380-6-6 10.1111/epi.13354 10.1111/epi.13653 10.1212/01.WNL.0000125184.88797.62 10.1016/j.clinph.2006.11.312 10.1111/ane.12732 10.1097/WNP.0000000000000166 10.1001/jamaneurol.2017.2459 10.1002/ana.24985 10.1001/jamaneurol.2019.4656 10.1097/WNP.0b013e3182784729 10.1001/jamaneurol.2013.6238 10.1111/epi.12653 10.1001/jamaneurol.2016.4990 10.1111/epi.12270 10.1016/S1474-4422(16)30137-5 10.1097/WNP.0000000000000806 10.1007/s12028-020-00939-x 10.1097/CCM.0000000000003641 10.1001/jamaneurol.2020.2264 10.1212/WNL.0000000000006689 10.1212/01.wnl.0000436948.93399.2a 10.1002/ana.25249 10.1056/NEJMoa1905795 10.1016/S0140-6736(20)30611-5 10.1016/S0140-6736(19)30722-6 10.1016/S0140-6736(19)30724-X 10.1111/epi.16094 10.1007/s40261-015-0295-5 10.1016/j.seizure.2013.07.011 10.1111/ane.13061 10.1111/epi.14494 10.1111/epi.16382 10.1016/j.seizure.2016.03.003 10.1016/j.seizure.2012.11.004 10.1186/s12883-016-0724-y 10.1111/epi.13013 10.1111/ane.12414 10.1016/j.eplepsyres.2018.12.001 10.1002/epi4.12383 10.1016/j.seizure.2020.03.002 10.1016/j.yebeh.2020.107286 10.1007/s40263-020-00770-0 10.1016/j.yebeh.2017.03.018 10.1016/j.spen.2014.12.006 10.1016/S1474-4422(15)00042-3 10.1007/s40265-015-0454-2 10.1007/s11940-016-0394-5 10.3390/jcm5050049 10.1007/s40265-017-0859-1 10.1002/phar.2229 10.1007/s40263-019-00690-8 10.1007/s11940-015-0340-y 10.1007/s12028-012-9790-1 10.1111/j.1468-1331.2009.02917.x 10.1007/s12028-012-9695-z 10.5698/1535-7597-16.1.48 10.1007/s12028-010-9337-2 10.1016/j.cnp.2019.07.001 10.1038/nrn1430 10.1016/S0074-7742(06)81006-8 10.1080/14656566.2018.1541349 10.1212/WNL.0000000000001940 10.1111/epi.14016 10.1111/epi.14022 10.1001/jamaneurol.2017.4382 10.1212/WNL.0000000000000009 10.5698/1535-7511-15.6.313 10.1097/CCM.0000000000000881 10.1212/WNL.0000000000003224 10.1111/epi.14706 10.1111/ane.13302
Drugs Bravo P, Vaddiparti A et. al.

Apr 8th, 2021 - Most seizures in critically ill patients are nonconvulsive. A significant number of neurological and medical conditions can be complicated by nonconvulsive seizures (NCSs) and nonconvulsive status epilepticus (NCSE), with brain infections, hemorrh...

The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced sta...
https://doi.org/10.1016/j.brainres.2021.147468
Brain Research; Cao H, Zhang L et. al.

Apr 8th, 2021 - Status epilepticus (SE) is a neurological emergency. The pathological hallmark of neuronal damage after epileptic seizures could be the chain reaction of oxygen free radicals. Hydroxylated fullerenes (HFs) are novel and effective free radical scav...

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Guidelines  11 results

New Guideline for Treatment of Prolonged Seizures in Children and Adults
https://www.aesnet.org/about_aes/press_releases/guidelines2016
American Epilepsy Society

Feb 8th, 2016 - The guideline, which reviewed all available adult and pediatric evidence, provides a treatment algorithm that comprises three phases of treatment. It also offers evidence-based answers to the effectiveness, safety and tolerability questions regard.

Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults:...
http://www.epilepsycurrents.org/doi/full/10.5698/1535-7597-16.1.48?code=amep-site
Tracy Glauser

Feb 8th, 2016 - Despite the paucity of well-designed randomized controlled trials, practical conclusions and an integrated treatment algorithm for the treatment of convulsive status epilepticus across the age spectrum (infants through adults) can be constructed.

Consensus statement on continuous EEG in critically ill adults and children, part I: in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435533
Journal of Clinical Neurophysiology : Official Publicatio... Herman ST, Abend NS et. al.

Jan 29th, 2015 - Critical Care Continuous EEG (CCEEG) is a common procedure to monitor brain function in patients with altered mental status in intensive care units. There is significant variability in patient populations undergoing CCEEG and in technical specific...

Recommendations on the use of EEG monitoring in critically ill patients: consensus stat...
https://doi.org/10.1007/s00134-013-2938-4
Intensive Care Medicine; Claassen J, Taccone FS et. al.

May 8th, 2013 - Recommendations for EEG monitoring in the ICU are lacking. The Neurointensive Care Section of the ESICM assembled a multidisciplinary group to establish consensus recommendations on the use of EEG in the ICU. A systematic review was performed and ...

EFNS guideline on the management of status epilepticus in adults.
https://doi.org/10.1111/j.1468-1331.2009.02917.x
European Journal of Neurology; Meierkord H, Boon P et. al.

Jan 6th, 2010 - The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to Januar...

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Drugs  73 results see all →

Clinicaltrials.gov  7,427 results

The Kv7 modulator, retigabine, is an efficacious antiseizure drug for delayed treatment...
https://doi.org/10.1016/j.neuroscience.2021.03.029
Neuroscience Barker BS, Spampanato J et. al.

Apr 9th, 2021 - Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant ...

Hippocampal and septal 5-HT1A receptor expression in two rat models of temporal lobe ep...
https://doi.org/10.1016/j.neuroscience.2021.03.026
Neuroscience Schönhoff K, von Rüden EL et. al.

Apr 9th, 2021 - Experimental and clinical data suggest an impact of serotonergic signaling on seizure susceptibility and epilepsy-associated psychiatric comorbidities. Previous µPET studies revealed increased binding of 5-HT1A receptor ligand [18F]MPPF in two rat...

Pharmacotherapy for Nonconvulsive Seizures and Nonconvulsive Status Epilepticus.
https://doi.org/10.1007/s40265-021-01502-4 10.1111/epi.13121 10.1001/archneur.1973.00490190019001 10.1001/archneur.1973.00490190028002 10.1001/archneur.1973.00490260026003 10.1111/j.1528-1157.1988.tb04226.x 10.1001/jama.1993.03510070076040 10.1056/NEJM199809173391202 10.1111/j.1528-1157.1999.tb02070.x 10.1002/ana.1018 10.1212/WNL.58.4.537 10.1136/jnnp.74.2.189 10.1097/01.nrl.0000162954.76053.d2 10.1016/S1474-4422(07)70074-1 10.1016/j.clinph.2017.01.015 10.1111/j.1528-1157.1998.tb01177.x 10.1212/WNL.46.4.1029 10.1212/WNL.50.3.735 10.1212/WNL.54.2.340 10.1046/j.1528-1157.2001.0420081031.x 10.1111/j.1528-1167.2005.00409.x 10.1007/s12028-013-9935-x 10.1038/nrneurol.2015.104 10.1111/epi.16277 10.1016/j.seizure.2004.06.001 10.1016/j.seizure.2013.08.003 10.1016/0920-1211(94)90062-0 10.1016/j.yebeh.2003.11.032 10.1111/j.1528-1157.1993.tb02123.x 10.1002/ana.410180303 10.1124/jpet.104.069146 10.1111/epi.14070 10.1001/archneur.55.1.119 10.1001/archneur.55.1.117 10.1212/WNL.47.1.83 10.1016/S0920-1211(97)00071-5 10.1212/WNL.52.4.746 10.1212/01.WNL.0000063316.47591.B4 10.1097/01.CCM.0000295667.66853.BC 10.1212/WNL.0b013e3181f07334 10.1212/WNL.0b013e31829c5cfe 10.1093/brain/awu042 10.1212/WNL.0000000000000082 10.1212/WNL.0000000000002281 10.1002/ana.24606 10.1001/jamaneurol.2016.5325 10.1016/j.clinph.2018.08.015 10.1007/s12028-020-00944-0 10.1523/JNEUROSCI.17-19-07532.1997 10.1056/NEJMoa002141 10.1186/1865-1380-6-6 10.1111/epi.13354 10.1111/epi.13653 10.1212/01.WNL.0000125184.88797.62 10.1016/j.clinph.2006.11.312 10.1111/ane.12732 10.1097/WNP.0000000000000166 10.1001/jamaneurol.2017.2459 10.1002/ana.24985 10.1001/jamaneurol.2019.4656 10.1097/WNP.0b013e3182784729 10.1001/jamaneurol.2013.6238 10.1111/epi.12653 10.1001/jamaneurol.2016.4990 10.1111/epi.12270 10.1016/S1474-4422(16)30137-5 10.1097/WNP.0000000000000806 10.1007/s12028-020-00939-x 10.1097/CCM.0000000000003641 10.1001/jamaneurol.2020.2264 10.1212/WNL.0000000000006689 10.1212/01.wnl.0000436948.93399.2a 10.1002/ana.25249 10.1056/NEJMoa1905795 10.1016/S0140-6736(20)30611-5 10.1016/S0140-6736(19)30722-6 10.1016/S0140-6736(19)30724-X 10.1111/epi.16094 10.1007/s40261-015-0295-5 10.1016/j.seizure.2013.07.011 10.1111/ane.13061 10.1111/epi.14494 10.1111/epi.16382 10.1016/j.seizure.2016.03.003 10.1016/j.seizure.2012.11.004 10.1186/s12883-016-0724-y 10.1111/epi.13013 10.1111/ane.12414 10.1016/j.eplepsyres.2018.12.001 10.1002/epi4.12383 10.1016/j.seizure.2020.03.002 10.1016/j.yebeh.2020.107286 10.1007/s40263-020-00770-0 10.1016/j.yebeh.2017.03.018 10.1016/j.spen.2014.12.006 10.1016/S1474-4422(15)00042-3 10.1007/s40265-015-0454-2 10.1007/s11940-016-0394-5 10.3390/jcm5050049 10.1007/s40265-017-0859-1 10.1002/phar.2229 10.1007/s40263-019-00690-8 10.1007/s11940-015-0340-y 10.1007/s12028-012-9790-1 10.1111/j.1468-1331.2009.02917.x 10.1007/s12028-012-9695-z 10.5698/1535-7597-16.1.48 10.1007/s12028-010-9337-2 10.1016/j.cnp.2019.07.001 10.1038/nrn1430 10.1016/S0074-7742(06)81006-8 10.1080/14656566.2018.1541349 10.1212/WNL.0000000000001940 10.1111/epi.14016 10.1111/epi.14022 10.1001/jamaneurol.2017.4382 10.1212/WNL.0000000000000009 10.5698/1535-7511-15.6.313 10.1097/CCM.0000000000000881 10.1212/WNL.0000000000003224 10.1111/epi.14706 10.1111/ane.13302
Drugs Bravo P, Vaddiparti A et. al.

Apr 8th, 2021 - Most seizures in critically ill patients are nonconvulsive. A significant number of neurological and medical conditions can be complicated by nonconvulsive seizures (NCSs) and nonconvulsive status epilepticus (NCSE), with brain infections, hemorrh...

The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced sta...
https://doi.org/10.1016/j.brainres.2021.147468
Brain Research; Cao H, Zhang L et. al.

Apr 8th, 2021 - Status epilepticus (SE) is a neurological emergency. The pathological hallmark of neuronal damage after epileptic seizures could be the chain reaction of oxygen free radicals. Hydroxylated fullerenes (HFs) are novel and effective free radical scav...

see more →

News  277 results

Ketamine to the Rescue in Status Epilepticus?
https://www.staging.medscape.com/viewarticle/931936

Jun 16th, 2020 - This transcript has been edited for clarity. Robert D. Glatter, MD: Hello and welcome. I'm Dr Robert Glatter, advisor and editorial board member for Medscape Emergency Medicine. Managing patients with refractory status epilepticus can be quite cha...

Ketamine to the Rescue in Status Epilepticus?
https://www.medscape.com/viewarticle/931936

Jun 16th, 2020 - This transcript has been edited for clarity. Robert D. Glatter, MD: Hello and welcome. I'm Dr Robert Glatter, advisor and editorial board member for Medscape Emergency Medicine. Managing patients with refractory status epilepticus can be quite cha...

California researchers work to update EMS status epilepticus protocols
https://www.mdedge.com/internalmedicine/article/214548/epilepsy-seizures/california-researchers-work-update-ems-status?channel=53
M. Alexander Otto

Dec 19th, 2019 - BALTIMORE – Investigators from the University of California, San Francisco, are working with medical directors across the state to update county emergency medical services protocols to ensure patients in status epilepticus get 10 mg IM midazolam i.

Three Anticonvulsants Show Similar Efficacy in Status Epilepticus
https://www.staging.medscape.com/viewarticle/921947

Nov 27th, 2019 - Three anticonvulsant drugs used in benzodiazepine-refractory convulsive status epilepticus have been shown to have very similar levels of efficacy. Use of levetiracetam, fosphenytoin, and valproate each led to seizure cessation and improved alertn...

Three Anticonvulsants Show Similar Efficacy in Status Epilepticus
https://www.medscape.com/viewarticle/921947

Nov 27th, 2019 - Three anticonvulsant drugs used in benzodiazepine-refractory convulsive status epilepticus have been shown to have very similar levels of efficacy. Use of levetiracetam, fosphenytoin, and valproate each led to seizure cessation and improved alertn...

see more →

Patient Education  1 results see all →