ALLMedicine™ Status Epilepticus Center

Jun 28th, 2022 - Purpose: A patient with primary CoQ10 deficiency associated with the c.901 C > T (p.R301W) (rs140246430) homozygous missense pathogenic variant in the COQ8A gene, who presented with recurrent status epilepticus, stroke-like lesions, and hypertroph...

Jun 26th, 2022 - Long non-coding RNAs (lncRNAs) have been confirmed to be involved in epilepsy development. It has been reported that lncRNA ZFAS1 plays a vital regulatory role in epilepsy progression. Therefore, the role and molecular mechanism of ZFAS1 in epilep...

Jun 25th, 2022 - Patients with refractory status epilepticus (RSE) have failed treatment with benzodiazepines and ≥1 second-line intravenous (IV) anti-seizure medication (ASM). Guidelines recommend IV anesthesia when second-line ASMs have failed, but potential har...

Jun 23rd, 2022 - Untreated pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency, characterized by a range of seizure types, is "classic" (i.e., seizure onset in the neonatal period) in about 90% of affected individuals and "late onset" (seizure onset after the ne...

Jun 23rd, 2022 - To identify differences in clinical characteristics between patients with out-of-hospital and in-hospital status epilepticus (SE) onset, and to evaluate the influence of SE onset setting on 30-day mortality and SE cessation. We included consecutiv...

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

Jan 30th, 2015 - Critical Care Continuous EEG (CCEEG) is a common procedure to monitor brain function in patients with altered mental status in intensive care units. There is significant variability in patient populations undergoing CCEEG and in technical specific...

Jan 7th, 2010 - The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to Januar...

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including the risk of pregnancy complications or other medical problems during pregnancy in WWE compared to other women, change in se...

Jun 14th, 2022 - Non-traumatic, acute central nervous system (CNS) disorders are amongst the most frequent emergencies in childhood. In Switzerland, CNS disorders are the top ranking presentation of critically ill children. Many pediatric neurological emergencies ...

Jun 13th, 2022 - Epilepsy is a chronic neurological disease characterized by the occurrence of intermittent seizures, often isolated, but which can progress to status epilepticus (SE) when the seizures are repeated at short intervals without recovery of consciousn...

Jun 7th, 2022 - Long term protocol: Perform non-invasive neuro-navigated repeated Transcranial Magnetic Stimulation (rTMS) at low frequencies (LF) with to reduce the occurrence of seizures over time. Seizure reduction and improvements in the quality of life in pa...

May 5th, 2022 - This study is to investigate the effects of different treatment characteristics regarding the use of intravenous anesthetic drugs (IVADs) as a rescue treatment for refractory Status epilepticus (RSE) on course and outcome. A retrospective data ext...

May 3rd, 2022 - This is an open-label study consisting of a screening period (1 day), 4-day treatment period (96 hours) followed by a 1-day dose taper period (24 hours), a 2-day acute follow-up period, and a 3 week extended follow-up period. On Day 1 of treatment...

Apr 25th, 2022 - NEW YORK (Reuters Health) - In patients with status epilepticus that is "less damaging" to the brain, a three-factor scoring system may help predict post-discharge outcomes, researchers suggest. As reported in JAMA Neurology, Dr. Christoph Beier o...

Mar 10th, 2022 - As neurologists in war-torn Ukraine plead for assistance, professional societies around the world are taking action. "There are children in dire need of their antiseizure medications (ASMs) going into status epilepticus," tweeted pediatric neurolo...

Feb 2nd, 2022 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner reporting on the recent, virtually held American Epilepsy Society meeting. With me today is Dr Charles Szabo, professor and chief of epile...

Dec 13th, 2021 - Patients who experience stroke have a "very high" risk of epilepsy 1 year later, new research shows. Results from a large registry study reveals patients who experienced a severe intracerebral hemorrhage (ICH) had an almost 10% chance of developin...

Nov 17th, 2021 - Prehospital treatment of people with status epilepticus rarely was consistent with expert guidelines, an analysis of emergency medical service (EMS) agency records showed. Initial treatment was concordant with guidelines in only 3.9% of 9,176 EMS ...