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ALLMedicine™ Creutzfeldt-jakob Disease Center

Research & Reviews  2,017 results

Diffusion-Weighted Imaging is Key to Diagnosing Specific Diseases.
https://doi.org/10.1016/j.mric.2021.02.001
Magnetic Resonance Imaging Clinics of North America; Tokumaru AM, Saito Y et. al.

Apr 27th, 2021 - This article reviews diseases for which persistent signal abnormalities on diffusion-weighted imaging are the key to their diagnosis. Specifically, updated knowledge regarding the neuroimaging patterns of the following diseases is summarized: spor...

Teaching Video NeuroImages: Optic Ataxia as the Presenting Sign of the Heidenhain Varia...
https://doi.org/10.1212/WNL.0000000000012057
Neurology Yang SL, Han X et. al.

Apr 27th, 2021 - Teaching Video NeuroImages: Optic Ataxia as the Presenting Sign of the Heidenhain Variant of Creutzfeldt-Jakob Disease.|2021|Yang SL,Han X,Dong Q,|

TREM2 expression in the brain and biological fluids in prion diseases.
https://doi.org/10.1007/s00401-021-02296-1 10.3389/fneur.2019.00280.eCollection 10.1186/s13195-019-0562-4 10.1146/annurev.pathol.3.121806.154326 10.1016/j.jneuroim.2018.03.003 10.1007/BF00308809 10.1007/s00401-006-0127-z 10.1001/jamaneurol.2013.6237 10.1007/s00401-010-0760-4 10.1128/mBio.00393-20 10.1038/ncomms6821 10.1186/s12974-020-01853-x 10.1186/s13024-018-0262-8 10.1007/s12035-015-9133-2 10.1016/j.cell.2020.05.003 10.1111/bpa.12564 10.1016/B978-0-12-385157-4.00585-6 10.1093/bmb/66.1.213 10.1212/CON.0000000000000251 10.1016/j.neurobiolaging.2008.01.007 10.1016/j.neurobiolaging.2013.06.005 10.1056/NEJMoa1211851 10.1186/s13195-016-0182-1 10.1212/WNL.0000000000005860 10.1186/s13024-016-0071-x 10.3233/JAD-2009-1075 10.1056/NEJMoa1211103 10.1016/j.neurobiolaging.2015.01.021 10.1016/j.nbd.2004.09.007 10.1126/scitranslmed.3009093 10.1111/ene.13389 10.1007/s00439-005-0020-1 10.1007/s00415-009-5163-x 10.1007/s12035-017-0479-5 10.3389/fnagi.2014.00198 10.1002/alz.12133 10.1016/j.jalz.2015.10.009 10.1186/s13024-017-0226-4 10.3390/biom10020290 10.1111/nan.12175 10.1007/s11910-017-0743-0 10.1111/bpa.12190 10.1186/s13024-016-0137-9 10.1007/s00401-011-0845-8 10.1002/ana.23589 10.1016/j.jalz.2011.03.005 10.1093/nar/gkaa616 10.1111/j.1750-3639.1998.tb00172.x 10.1177/1352458515624558 10.1007/s00401-012-1002-8 10.1002/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W 10.1093/brain/awn217 10.1007/s00401-016-1533-5 10.1016/S1474-4422(12)70063-7 10.1016/j.neurobiolaging.2018.10.022 10.1186/1750-1326-8-19 10.1186/1471-2105-12-77 10.1212/01.wnl.0000230159.67128.00 10.1007/s00415-006-0472-9 10.15252/emmm.201707672 10.1046/j.1471-4159.2002.01243.x 10.1007/s12035-015-9167-5 10.1016/j.jalz.2014.05.1751 10.1084/jem.20171529 10.1001/jamaneurol.2019.1071 10.1038/srep38737 10.15252/emmm.201506123 10.1186/s13024-018-0301-5 10.1016/S0140-6736(18)30481-1 10.1016/j.mcn.2018.12.003 10.1073/pnas.1901947116 10.1186/s12974-019-1531-3 10.1084/jem.20141732 10.1002/ana.410430109 10.1093/brain/awp191 10.1016/j.jalz.2017.12.008 10.1111/ane.12845 10.1038/s41467-019-09118-9 10.1016/j.neurobiolaging.2015.02.019
Acta Neuropathologica; Diaz-Lucena D, Kruse N et. al.

Apr 21st, 2021 - Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several neurodegenerative diseases. Its soluble form (sTREM2) results f...

Non-white cases of sporadic Creutzfeldt-Jakob disease: A 28 year review of United Kingd...
https://doi.org/10.1016/j.jns.2021.117416
Journal of the Neurological Sciences; Langlands G, Mackenzie J et. al.

Apr 11th, 2021 - Descriptions of sporadic Creutzfeldt-Jakob disease (sCJD) in non-White populations are limited. Improved understanding may aid diagnoses and case ascertainment within surveillance programmes. We aimed to: 1) Ascertain the proportion of sCJD cases ...

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017635
Acta Neuropathologica Communications; Ali T, Hannaoui S et. al.

Apr 2nd, 2021 - Prion diseases are fatal, infectious, and incurable neurodegenerative disorders caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform (PrPSc). In humans, there are sporadic, genetic and infectious etiologies, with s...

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Clinicaltrials.gov  2,125 results

Diffusion-Weighted Imaging is Key to Diagnosing Specific Diseases.
https://doi.org/10.1016/j.mric.2021.02.001
Magnetic Resonance Imaging Clinics of North America; Tokumaru AM, Saito Y et. al.

Apr 27th, 2021 - This article reviews diseases for which persistent signal abnormalities on diffusion-weighted imaging are the key to their diagnosis. Specifically, updated knowledge regarding the neuroimaging patterns of the following diseases is summarized: spor...

Teaching Video NeuroImages: Optic Ataxia as the Presenting Sign of the Heidenhain Varia...
https://doi.org/10.1212/WNL.0000000000012057
Neurology Yang SL, Han X et. al.

Apr 27th, 2021 - Teaching Video NeuroImages: Optic Ataxia as the Presenting Sign of the Heidenhain Variant of Creutzfeldt-Jakob Disease.|2021|Yang SL,Han X,Dong Q,|

TREM2 expression in the brain and biological fluids in prion diseases.
https://doi.org/10.1007/s00401-021-02296-1 10.3389/fneur.2019.00280.eCollection 10.1186/s13195-019-0562-4 10.1146/annurev.pathol.3.121806.154326 10.1016/j.jneuroim.2018.03.003 10.1007/BF00308809 10.1007/s00401-006-0127-z 10.1001/jamaneurol.2013.6237 10.1007/s00401-010-0760-4 10.1128/mBio.00393-20 10.1038/ncomms6821 10.1186/s12974-020-01853-x 10.1186/s13024-018-0262-8 10.1007/s12035-015-9133-2 10.1016/j.cell.2020.05.003 10.1111/bpa.12564 10.1016/B978-0-12-385157-4.00585-6 10.1093/bmb/66.1.213 10.1212/CON.0000000000000251 10.1016/j.neurobiolaging.2008.01.007 10.1016/j.neurobiolaging.2013.06.005 10.1056/NEJMoa1211851 10.1186/s13195-016-0182-1 10.1212/WNL.0000000000005860 10.1186/s13024-016-0071-x 10.3233/JAD-2009-1075 10.1056/NEJMoa1211103 10.1016/j.neurobiolaging.2015.01.021 10.1016/j.nbd.2004.09.007 10.1126/scitranslmed.3009093 10.1111/ene.13389 10.1007/s00439-005-0020-1 10.1007/s00415-009-5163-x 10.1007/s12035-017-0479-5 10.3389/fnagi.2014.00198 10.1002/alz.12133 10.1016/j.jalz.2015.10.009 10.1186/s13024-017-0226-4 10.3390/biom10020290 10.1111/nan.12175 10.1007/s11910-017-0743-0 10.1111/bpa.12190 10.1186/s13024-016-0137-9 10.1007/s00401-011-0845-8 10.1002/ana.23589 10.1016/j.jalz.2011.03.005 10.1093/nar/gkaa616 10.1111/j.1750-3639.1998.tb00172.x 10.1177/1352458515624558 10.1007/s00401-012-1002-8 10.1002/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W 10.1093/brain/awn217 10.1007/s00401-016-1533-5 10.1016/S1474-4422(12)70063-7 10.1016/j.neurobiolaging.2018.10.022 10.1186/1750-1326-8-19 10.1186/1471-2105-12-77 10.1212/01.wnl.0000230159.67128.00 10.1007/s00415-006-0472-9 10.15252/emmm.201707672 10.1046/j.1471-4159.2002.01243.x 10.1007/s12035-015-9167-5 10.1016/j.jalz.2014.05.1751 10.1084/jem.20171529 10.1001/jamaneurol.2019.1071 10.1038/srep38737 10.15252/emmm.201506123 10.1186/s13024-018-0301-5 10.1016/S0140-6736(18)30481-1 10.1016/j.mcn.2018.12.003 10.1073/pnas.1901947116 10.1186/s12974-019-1531-3 10.1084/jem.20141732 10.1002/ana.410430109 10.1093/brain/awp191 10.1016/j.jalz.2017.12.008 10.1111/ane.12845 10.1038/s41467-019-09118-9 10.1016/j.neurobiolaging.2015.02.019
Acta Neuropathologica; Diaz-Lucena D, Kruse N et. al.

Apr 21st, 2021 - Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several neurodegenerative diseases. Its soluble form (sTREM2) results f...

Non-white cases of sporadic Creutzfeldt-Jakob disease: A 28 year review of United Kingd...
https://doi.org/10.1016/j.jns.2021.117416
Journal of the Neurological Sciences; Langlands G, Mackenzie J et. al.

Apr 11th, 2021 - Descriptions of sporadic Creutzfeldt-Jakob disease (sCJD) in non-White populations are limited. Improved understanding may aid diagnoses and case ascertainment within surveillance programmes. We aimed to: 1) Ascertain the proportion of sCJD cases ...

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017635
Acta Neuropathologica Communications; Ali T, Hannaoui S et. al.

Apr 2nd, 2021 - Prion diseases are fatal, infectious, and incurable neurodegenerative disorders caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform (PrPSc). In humans, there are sporadic, genetic and infectious etiologies, with s...

see more →

News  107 results

Fast Five Quiz: Alzheimer Disease Differential Diagnosis and Workup
https://reference.medscape.com/viewarticle/912046_2

May 22nd, 2019 - Answer 1/5 Memory-sparing can be observed with which of the following in the early stages of dementia? Your peers chose: Alzheimer disease and frontotemporal dementia (FTD) 0% Chronic traumatic encephalopathy (CTE) and FTD 0% Dementia with Lewy bo...

CSF and plasma biomarkers predict survival in sporadic Creutzfeldt-Jakob disease
https://www.mdedge.com/neurology/article/200209/rare-diseases/csf-and-plasma-biomarkers-predict-survival-sporadic/page/0/1?channel=27970

May 6th, 2019 - Plasma total tau was associated with survival In all, 188 patients were included in the analysis. The population’s mean age was 63.

Fast Five Quiz: Organ Donation and Transplant
https://reference.medscape.com/viewarticle/905709_2

Dec 5th, 2018 - Answer 1/5 Although regional transplant centers have varying sets of absolute and relative criteria for excluding potential donors, which of the following is currently considered an absolute contraindication in a deceased donor, according to the N...

Eye Testing May Aid Early Diagnosis of Creutzfeldt-Jakob Disease
https://www.medscape.com/viewarticle/905720

Nov 27th, 2018 - Eye examinations may aid clinicians in the diagnosis of sporadic Creutzfeldt-Jacob disease (sCJD), results of a small postmortem study show. In an evaluation of the eyes and brains of 11 sCJD patients, investigators found prion seeding in all eyes...

Eye Testing May Aid Early Diagnosis of Creutzfeldt-Jakob Disease
https://www.staging.medscape.com/viewarticle/905720

Nov 27th, 2018 - Eye examinations may aid clinicians in the diagnosis of sporadic Creutzfeldt-Jacob disease (sCJD), results of a small postmortem study show. In an evaluation of the eyes and brains of 11 sCJD patients, investigators found prion seeding in all eyes...

see more →

Patient Education  13 results see all →