ALLMedicine™ Kuru Center
Research & Reviews 97 results
https://doi.org/10.1146/annurev-genet-120213-092352
Annual Review of Genetics; Mead S, Lloyd S et. al.
Sep 20th, 2019 - Mammalian prion diseases are a group of neurodegenerative conditions caused by infection of the central nervous system with proteinaceous agents called prions, including sporadic, variant, and iatrogenic Creutzfeldt-Jakob disease; kuru; inherited ...
https://doi.org/10.1055/s-0039-1687841
Seminars in Neurology; Baldwin KJ, Correll CM
Sep 18th, 2019 - Prion diseases are a phenotypically diverse set of disorders characterized by protease-resistant abnormally shaped proteins known as prions. There are three main groups of prion diseases, termed sporadic (Creutzfeldt-Jakob disease [CJD], sporadic ...
https://doi.org/10.1097/QCO.0000000000000552
Current Opinion in Infectious Diseases; Wang H, Rhoads DD et. al.
Apr 22nd, 2019 - Prion diseases are rapidly progressive neurodegenerative conditions that can be difficult to diagnose and are transmissible under specific circumstances. The authors will provide background regarding prion disease and focus on diagnostic tools. Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264140
PLoS Pathogens; Keller A, Nuvolone M et. al.
Nov 29th, 2018 - Transmissible spongiform encephalopathies (TSEs) are caused by the prion, which consists essentially of PrPSc, an aggregated, conformationally modified form of the cellular prion protein (PrPC). Although TSEs can be experimentally transmitted by i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277180
Prion Furukawa F, Sanjo N et. al.
Nov 5th, 2018 - Although colocalization of amyloid β (Aβ) with prion protein (PrP) in the kuru plaque has previously been observed in the brain of prion diseases patients, the participating Aβ species has not been identified. Here, we present an immunohistochemic...
Clinicaltrials.gov 103 results
https://doi.org/10.1146/annurev-genet-120213-092352
Annual Review of Genetics; Mead S, Lloyd S et. al.
Sep 20th, 2019 - Mammalian prion diseases are a group of neurodegenerative conditions caused by infection of the central nervous system with proteinaceous agents called prions, including sporadic, variant, and iatrogenic Creutzfeldt-Jakob disease; kuru; inherited ...
https://doi.org/10.1055/s-0039-1687841
Seminars in Neurology; Baldwin KJ, Correll CM
Sep 18th, 2019 - Prion diseases are a phenotypically diverse set of disorders characterized by protease-resistant abnormally shaped proteins known as prions. There are three main groups of prion diseases, termed sporadic (Creutzfeldt-Jakob disease [CJD], sporadic ...
https://doi.org/10.1097/QCO.0000000000000552
Current Opinion in Infectious Diseases; Wang H, Rhoads DD et. al.
Apr 22nd, 2019 - Prion diseases are rapidly progressive neurodegenerative conditions that can be difficult to diagnose and are transmissible under specific circumstances. The authors will provide background regarding prion disease and focus on diagnostic tools. Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264140
PLoS Pathogens; Keller A, Nuvolone M et. al.
Nov 29th, 2018 - Transmissible spongiform encephalopathies (TSEs) are caused by the prion, which consists essentially of PrPSc, an aggregated, conformationally modified form of the cellular prion protein (PrPC). Although TSEs can be experimentally transmitted by i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277180
Prion Furukawa F, Sanjo N et. al.
Nov 5th, 2018 - Although colocalization of amyloid β (Aβ) with prion protein (PrP) in the kuru plaque has previously been observed in the brain of prion diseases patients, the participating Aβ species has not been identified. Here, we present an immunohistochemic...
News 5 results
https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/5611
May 9th, 2007 - Action Points Explain to interested patients that prions -- misfolded proteins -- have been implicated in a range of diseases, including Creutzfeldt-Jakob disease and kuru in humans. Note that this basic research study finds that small sections of...
https://www.medpagetoday.com/genetics/generalgenetics/3599
Jun 22nd, 2006 - Action Points Explain to interested patients that this study suggests that the incubation period for variant Creutzfeldt-Jakob disease, the human form of so-called mad-cow disease, could last many decades, based on evidence from the study of kuru,...
https://www.mdedge.com/familymedicine/article/28330/infectious-diseases/vcjd-may-be-more-widespread-projected-prion
Family Practice News; Jonathan Gardner
Variant Creutzfeldt-Jakob disease could have an incubation time of 30 years or longer and could affect a wider population than currently forecast, according to new research on patients with a similar human prion disease. Researchers examined 11 re.
https://www.mdedge.com/ccjm/article/93229/kuru-and-mad-cow-disease-understanding-prion-theory
G. Richard Olds, MD
ABSTRACT A preponderance of evidence indicates that several neurodegenerative disorders are caused by prions: abnormally folded proteins that can induce abnormal folding in other normal protein molecules. Further, these “infections” can cross some.
https://www.staging.medscape.com/viewarticle/911244_5
Prion Disease • Neuropathology: Misfolded prions are proteinaceous infectious particles which cause several devastating neurodegenerative diseases, including Creutzfeldt–Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann–Straussler–Sche...