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ALLMedicine™ Creutzfeldt-jakob Disease Center

Research & Reviews  721 results

COVID-19-associated encephalitis or Creutzfeldt-Jakob disease: a case report.
https://doi.org/10.2217/nmt-2021-0025
Neurodegenerative Disease Management; Tayyebi G, Malakouti SK et. al.

Dec 3rd, 2021 - Background: Accurate diagnosis and management of patients with rapidly progressive dementia may be challenging during the COVID-19 pandemic, which has negatively influenced the diagnostic performances, medical resource allocation and routine care ...

Characteristics of Chinese patients with genetic CJD who have E196A or E196K mutation i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593757
BMJ Open; Shi Q, Xiao K et. al.

Nov 17th, 2021 - Two different mutations at codon 196, namely E196A and E196K, have been reported to be related to genetic Creutzfeldt-Jakob disease (CJD). We aimed to comparatively analyse the features of Chinese patients with these two mutations from the CJD sur...

The role of microglia in prion diseases and possible therapeutic targets: a literature ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583147
Prion de Melo ASLF, Lima JLD et. al.

Nov 10th, 2021 - Creutzfeldt-Jakob disease (CJD) is a rare and fatal condition that leads to progressive neurodegeneration due to gliosis, vacuolation of central nervous system tissue, and loss of neurons. Microglia play a crucial role in maintaining Central Nervo...

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Clinicaltrials.gov  1 results

PRION-1: Quinacrine for Human Prion Disease
https://clinicaltrials.gov/ct2/show/NCT00104663

Apr 7th, 2015 - The human prion diseases have been traditionally classified into Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker (GSS) disease and kuru. They can alternatively be classified into three causal categories: sporadic, acquired and inhe...

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News  65 results

Prion Reduction Shows Promise in Mice With Prion Disease
https://www.staging.medscape.com/viewarticle/935529

Aug 12th, 2020 - NEW YORK (Reuters Health) - Preclinical studies suggest that prion-protein reduction may provide therapeutic benefit in prion diseases, according to a multinational group of researchers. "Our study shows in several different ways that in rodent mo...

COVID-19: SaBTO Recommendations on Use of Plasma Donations
https://www.staging.medscape.com/viewarticle/932068

Jun 10th, 2020 - Recommendations from the Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) on the use of convalescent plasma to treat COVID-19 have been published, ahead of planned clinical trials to commence this month. SaBTO said it is satis...

COVID-19: SaBTO Recommendations on Use of Plasma Donations
https://www.medscape.com/viewarticle/932068

Jun 10th, 2020 - Recommendations from the Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) on the use of convalescent plasma to treat COVID-19 have been published, ahead of planned clinical trials to commence this month. SaBTO said it is satis...

Fast Five Quiz: Alzheimer Disease Differential Diagnosis and Workup
https://reference.medscape.com/viewarticle/912046_2

May 23rd, 2019 - Answer 1/5 Memory-sparing can be observed with which of the following in the early stages of dementia? Your peers chose: Alzheimer disease and frontotemporal dementia (FTD) 0% Chronic traumatic encephalopathy (CTE) and FTD 0% Dementia with Lewy bo...

CSF and plasma biomarkers predict survival in sporadic Creutzfeldt-Jakob disease
https://www.mdedge.com/neurology/article/200209/rare-diseases/csf-and-plasma-biomarkers-predict-survival-sporadic/page/0/1?channel=27970

May 6th, 2019 - Plasma total tau was associated with survival In all, 188 patients were included in the analysis. The population’s mean age was 63.

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Patient Education  9 results see all →