ALLMedicine™ Creutzfeldt-jakob Disease Center

Jun 27th, 2022 - Inherited prion diseases (IPD) are a set of rare neurodegenerative diseases that are always caused by mutation of the prion protein gene (PRNP). These are highly heterogeneous in clinical presentation and best described by the specific gene mutati...

Jun 26th, 2022 - In 2005, the blood service in England notified 101 donors by letter that they may be at risk of variant Creutzfeldt-Jakob disease (vCJD) because a recipient of their blood later developed vCJD. Donor experience of the notification was studied in a...

Jun 24th, 2022 - Autoimmune encephalitis (AE) is a potentially treatable cause of rapidly progressive dementia (RPD) that may mimic Creutzfeldt-Jakob disease (CJD). Alzheimer disease (AD) cerebrospinal fluid (CSF) biomarkers may discriminate CJD from AD, but utili...

Jun 24th, 2022 - Insomnia and thalamic involvement were frequently reported in patients with genetic Creutzfeldt-Jakob disease (gCJD) with E200K mutations, suggesting E200K might have discrepancy with typical sporadic CJD (sCJD). The study aimed to explore the cli...

Jun 7th, 2022 - Grey matter involvement is a well-known feature in sporadic Creutzfeldt-Jakob disease (sCJD), yet precise anatomy-based quantification of reduced diffusivity is still not fully understood. Default Mode Network (DMN) areas have been recently demons...

May 26th, 2022 - Encephalopathies are a group of central nervous system (CNS) affection with heterogeneous etiology. Several causes have been recognized including neurodegenerative, vascular, infectious, autoimmune, toxic or allergic affections or secondary to sys...

Dec 2nd, 2021 - A new fatty acid extracted from the pomegranate showed unexpectedly beneficial properties after nanotechnological processing. Encouraging effects of the new substance called nano-PSO led to design the present investigation. Indeed, the substance i...

May 19th, 2021 - This study will be the largest analysis of cerebrospinal fluid (CSF) α-synuclein in Rapid Eye Movement Behaviour Disorder (RBD) patients to date. In line with the The National CJD Research & Surveillance Unit (NCJDRSU)'s recent inclusion of a posi...

Aug 21st, 2019 - Screening and Consent - Index cases: Hospitalized patient with the diagnosis of severe CDAD At screening visit the study investigator(s) will explain the study in detail, answer any questions the candidate may have, and give the candidate a consen...

Oct 9th, 2018 - Objective To evaluate the success rate of iECG CVL tip confirmation by self-invented iECG connector wire. To compare quality of iECG tracing produced from both of self-invented iECG wire versus the Certodyn system. Materials, participants and stud...

Mar 24th, 2022 - About 1 in 6 patients with Creutzfeldt-Jakob disease (CJD) undergo surgery, raising the risk of iatrogenic transmission of this rare but universally fatal prion disease. In a retrospective analysis, researchers found that 26 of 121 (21%) patients ...

Aug 12th, 2020 - NEW YORK (Reuters Health) - Preclinical studies suggest that prion-protein reduction may provide therapeutic benefit in prion diseases, according to a multinational group of researchers. "Our study shows in several different ways that in rodent mo...

Jun 10th, 2020 - Recommendations from the Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) on the use of convalescent plasma to treat COVID-19 have been published, ahead of planned clinical trials to commence this month. SaBTO said it is satis...

Jun 10th, 2020 - Recommendations from the Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) on the use of convalescent plasma to treat COVID-19 have been published, ahead of planned clinical trials to commence this month. SaBTO said it is satis...

May 23rd, 2019 - Answer 1/5 Memory-sparing can be observed with which of the following in the early stages of dementia? Your peers chose: Alzheimer disease and frontotemporal dementia (FTD) 0% Chronic traumatic encephalopathy (CTE) and FTD 0% Dementia with Lewy bo...