ALLMedicine™ Neurosyphilis Center

Jun 1st, 2022 - Temporal arteritis is usually caused by giant cell arteritis (GCA). However, inflammation of the temporal artery can also occur secondary to autoimmune diseases or infections.We present a remarkable case of a man in his 70s with biopsy proven temp...

Jun 1st, 2022 - We present the case of a man exhibiting a clinical phenotype of behavioral variant of frontotemporal dementia (bvFTD). The man had developed psychiatric disturbances with verbal aggressiveness over a few months, followed by cognitive and frontal b...

Apr 29th, 2022 - Neurosyphilis can present in a myriad of ways, making the suspicion and diagnosis of this disease a great challenge for the clinician. We present a case of a 54-year-old patient who initially presented with cognitive changes and was eventually fou...

Apr 14th, 2022 - A panel of experts generated 5 "key questions" in the management of adult syphilis. A systematic literature review was conducted and tables of evidence were constructed to answer these questions. Available data suggest no clinical benefit to >1 do...

Apr 9th, 2022 - Accurate estimation of the burden of Plasmodium falciparum is essential for strategic planning for control and elimination. Due in part to the extreme heterogeneity in malaria exposure, immunity, other causes of disease, direct measurements of fev...

Nov 17th, 2021 - The syphilis epidemic is rampant around the world, and therapeutic options are restricted to an antibiotic, intramuscular (IM) BPG, which does not efficiently cross the blood-brain barrier. Treponema pallidum (T.p.), the bacteria that causes syphi...

Oct 27th, 2021 - Studies suggest that syphilis treatment failures may be more common in HIV infected patients than in patients without HIV infection and that treatment failures occur due to and/or are displayed as central nervous system (CNS) involvement. Very lit...

Jun 30th, 2021 - Charcot neuroarthropathy (CN) was first described by Jean-Martin Charcot in a patient with tabes dorsalis who recognized that peripheral neuropathy could lead to neuropathic joints. This condition has many names, including Charcot osteoarthropathy...

Feb 21st, 2021 - With the rising rates of STIs among gbMSM populations in Canada, there is an urgent need for novel interventions to prevent significant sequelae (e.g. neurosyphilis) and onward transmission of untreated infections. Despite longstanding public heal...

May 17th, 2016 - The investigators conducted a prospective, randomized, open label study at three clinical sites including Thomas Street Health Center and North West Clinic (Harris Health System), and the Michael E. DeBakey Veterans Affairs Medical Center in Houst...

Mar 15th, 2021 - "Symptoms, then, are in reality nothing but a cry from suffering organs" – Jean-Martin Charcot Nearly 130 years after his death, Jean-Martin Charcot's name still resonates with modern neurologists. The famed 19th century French physician made myri...

Aug 11th, 2020 - Answer 5/5 Which of the following infectious illnesses can cause mental status changes, such as psychosis, and should be ruled out in the differential diagnosis of schizophrenia? Your peers chose: HIV 0% Gonorrhea 0% Chlamydia 0% Cellulitis 0% HIV...

Nov 21st, 2019 - A 35-year-old man presents to the emergency room with nausea, tremors, and altered mental status. He recently stopped drinking alcohol cold-turkey. Could his issues be withdrawal or a lava lamp he drank? Watch an engaging analysis of this case abo...

Oct 25th, 2019 - To the Editor: A 46-year-old man with a history of AIDS (viral load, 28,186 copies/mL; CD4 count, 22 cells/μL) presented with a 40-lb weight loss over the last 6 months as well as dysphagia and a new-onset pruritic facial eruption of 1 week’s dura.

Sep 25th, 2018 - Rapidly increasing cases of newborn syphilis have reached their highest prevalence in 2 decades, according to a new report by the Centers for Disease Control and Prevention on sexually transmitted disease surveillance in 2017. U.