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About 438 results

ALLMedicine™ Venezuelan Equine Encephalitis Center

Research & Reviews  170 results

Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550936
Nature Basore K, Ma H et. al.

Oct 15th, 2021 - LDLRAD3 is a recently defined attachment and entry receptor for Venezuelan equine encephalitis virus (VEEV)1, a New World alphavirus that causes severe neurological disease in humans. Here we present near-atomic-resolution cryo-electron microscopy...

Exposing cryptic epitopes on the Venezuelan equine encephalitis virus E1 glycoprotein p...
https://doi.org/10.1016/j.virol.2021.09.007
Virology Calvert AE, Bennett SL et. al.

Oct 10th, 2021 - Eastern equine encephalitis virus (EEEV), western equine encephalitis virus (WEEV) and Venezuelan equine encephalitis virus (VEEV) can cause fatal encephalitis in humans and equids. Some MAbs to the E1 glycoprotein are known to be cross-reactive, ...

Polyplex nanomicelle delivery of self-amplifying RNA vaccine.
https://doi.org/10.1016/j.jconrel.2021.09.008
Journal of Controlled Release : Official Journal of the C... Chang YH, Lin MW et. al.

Sep 13th, 2021 - Self-amplifying RNA (SaRNA) is a burgeoning platform that exploits the replication machinery of alphaviruses such as Venezuelan equine encephalitis (VEE) virus or Sindbis virus (SIN). SaRNA has been used for development of human vaccines, but has ...

Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373297
Antimicrobial Agents and Chemotherapy; Haese NN, May NA et. al.

Jun 22nd, 2021 - Venezuelan equine encephalitis virus (VEEV) is a reemerging alphavirus that can cause encephalitis resulting in severe human morbidity and mortality. Using a high-throughput cell-based screen, we identified a quinolinone compound that protected ag...

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Clinicaltrials.gov  1 results

Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT01984983

Aug 26th, 2015 - The Phase I study will assess the basic safety, tolerability, and immunogenicity of a DNA-based Venezuelan equine encephalitis virus (VEEV)vaccine candidate delivered by electroporation . The study will enroll 40 healthy adult volunteers ages 18-4...

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News  4 results

Encephalitis: 2010 Outbreak in Panama Raises Concern
https://www.medscape.com/viewarticle/809754

Aug 21st, 2013 - Although a few cases of eastern equine encephalitis (EEE) in humans are reported each year in North America, the infection has been extremely rare in Latin America until 2010. In a report published online August 21 in the New England Journal of Me...

Encephalitis: 2010 Outbreak in Panama Raises Concern
https://www.staging.medscape.com/viewarticle/809754

Aug 21st, 2013 - Although a few cases of eastern equine encephalitis (EEE) in humans are reported each year in North America, the infection has been extremely rare in Latin America until 2010. In a report published online August 21 in the New England Journal of Me...

Evaluation in Nonhuman Primates of Vaccines against Ebola Virus
https://www.medscape.com/viewarticle/432519

Abstract and Introduction Ebola virus (EBOV) causes acute hemorrhagic fever that is fatal in up to 90% of cases in both humans and nonhuman primates. No vaccines or treatments are available for human use. We evaluated the effects in nonhuman prima...

Evaluation in Nonhuman Primates of Vaccines against Ebola Virus
https://www.medscape.com/viewarticle/432519_1

Abstract and Introduction Ebola virus (EBOV) causes acute hemorrhagic fever that is fatal in up to 90% of cases in both humans and nonhuman primates. No vaccines or treatments are available for human use. We evaluated the effects in nonhuman prima...

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