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About 32,352 results

ALLMedicine™ Amyotrophic Lateral Sclerosis Center

Research & Reviews  15,717 results

Utility of transoral motion-mode ultrasonography to detect tongue fasciculation in pati...
https://doi.org/10.1002/mus.27218
Muscle & Nerve; Hagiwara Y, Shimizu T et. al.

Mar 6th, 2021 - Increasing evidence suggests the utility of the submandibular approach for ultrasonography to detect tongue fasciculation in amyotrophic lateral sclerosis (ALS). We hypothesized that transoral motion-mode ultrasonography (TOMU) would be useful to ...

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to syna...
https://doi.org/10.1186/s13024-021-00433-8 10.1093/bioinformatics/btl140 10.1093/brain/awx024 10.1113/jphysiol.2004.077446 10.1523/JNEUROSCI.4101-05.2006 10.1002/ana.24731 10.1371/journal.pone.0085932 10.1038/35097565 10.1152/jn.00969.2010 10.1016/j.celrep.2017.09.028 10.1093/nar/gky1113 10.1002/stem.2388 10.1038/ncomms6999 10.1186/s40478-019-0797-0 10.1093/bioinformatics/bts635 10.1038/srep37968 10.1016/j.neuron.2017.11.028 10.1186/s40478-018-0579-0 10.1016/j.nbd.2013.06.005 10.1001/jamaneurol.2015.1872 10.1038/nrneurol.2016.140 10.7554/eLife.50333 10.1073/pnas.1405741111 10.1093/cercor/bhw185 10.1038/ncomms15132 10.1186/s40478-020-01030-4 10.1523/JNEUROSCI.5881-08.2009 10.1523/JNEUROSCI.0811-17.2017 10.1016/0896-6273(92)90075-O 10.1371/journal.pcbi.1004438 10.1093/bioinformatics/btt656 10.1523/JNEUROSCI.5410-13.2014 10.1113/JP270660 10.1016/j.clinph.2014.04.023 10.1111/ene.13295 10.1016/j.tins.2010.08.002 10.1016/j.celrep.2017.02.060 10.1523/JNEUROSCI.5231-04.2005 10.3109/21678421.2012.734520 10.1093/cercor/bhx301 10.1038/srep26181 10.1016/j.neuron.2015.11.018 10.1016/j.expneurol.2008.11.002 10.1038/nn.4065 10.1016/S0896-6273(00)80146-4 10.1093/cercor/bhu317 10.1126/scitranslmed.3007529 10.1002/mus.25047 10.1523/JNEUROSCI.0360-18.2018 10.1038/s41467-017-02729-0 10.1093/brain/awr355 10.1093/cercor/bhq152 10.1016/j.brainres.2018.02.011 10.1038/s41593-018-0080-x 10.1523/JNEUROSCI.1340-08.2008 10.1002/mus.20481 10.1093/brain/awn071 10.1001/jamaneurol.2015.2197 10.1016/j.celrep.2014.03.019 10.1136/jnnp-2012-304529 10.1016/0896-6273(94)90031-0 10.1038/nn.4257 10.1002/glia.23761
Molecular Neurodegeneration; Perkins EM, Burr K et. al.

Mar 5th, 2021 - Physiological disturbances in cortical network excitability and plasticity are established and widespread in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients, including those harbouring the C9ORF72 repeat expansion (C...

Evaluating person-centered factors associated with brain-computer interface access to a...
https://doi.org/10.1080/10400435.2021.1872737
Assistive Technology : the Official Journal of RESNA; Pitt KM, Brumberg JS

Mar 5th, 2021 - Current BCI-AAC systems largely utilize custom-made software and displays that may be unfamiliar to AAC stakeholders. Further, there is limited information available exploring the heterogenous profiles of individuals who may use BCI-AAC. Therefore...

Prevalence of pain in amyotrophic lateral sclerosis: a systematic review and meta-analy...
https://doi.org/10.1080/21678421.2021.1892765
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration; Hurwitz N, Radakovic R et. al.

Mar 4th, 2021 - Objectives: Physical pain is a known symptom in amyotrophic lateral sclerosis (ALS), but no systematically derived prevalence estimate is available. The aim of this study was to determine the pooled prevalence of pain in ALS, relative to its metho...

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Guidelines  9 results

Aquestive Therapeutics Receives FDA Approval for Exservan (riluzole) Oral Film
http://aquestive.com/aquestive-therapeutics-receives-fda-approval-for-exservan-riluzole-oral-film/

Nov 24th, 2019 - Aquestive Therapeutics, Inc. (NASDAQ: AQST), a specialty pharmaceutical company focused on developing and commercializing differentiated products to solve therapeutic problems, today announced that Exservan™ (riluzole) Oral Film received early-act...

Provisional best practices guidelines for the evaluation of bulbar dysfunction in amyot...
https://doi.org/10.1002/mus.26408
Muscle & Nerve; Pattee GL, Plowman EK et. al.

Jan 8th, 2019 - Universally established comprehensive clinical bulbar scales objectively assessing disease progression in amyotrophic lateral sclerosis (ALS) are currently lacking. The goal of this working group project is to design a best practice set of provisi...

MDA U.S. Neuromuscular Disease Registry
https://www.mda.org/services/neuromuscular-disease-registry
Muscular Dystrophy Association (USA)

Dec 31st, 2015 - In 2013, MDA launched the U. S.

EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)--rev...
https://doi.org/10.1111/j.1468-1331.2011.03501.x
European Journal of Neurology; , Andersen PM et. al.

Sep 14th, 2011 - The evidence base for the diagnosis and management of amyotrophic lateral sclerosis (ALS) is weak. To provide evidence-based or expert recommendations for the diagnosis and management of ALS based on a literature search and the consensus of an exp...

Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764728
Neurology Miller RG, Jackson CE et. al.

Oct 13th, 2009 - To systematically review evidence bearing on the management of patients with amyotrophic lateral sclerosis (ALS). The authors analyzed studies from 1998 to 2007 to update the 1999 practice parameter. Topics covered in this section include breaking...

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Drugs  31 results see all →

Clinicaltrials.gov  16,123 results

Utility of transoral motion-mode ultrasonography to detect tongue fasciculation in pati...
https://doi.org/10.1002/mus.27218
Muscle & Nerve; Hagiwara Y, Shimizu T et. al.

Mar 6th, 2021 - Increasing evidence suggests the utility of the submandibular approach for ultrasonography to detect tongue fasciculation in amyotrophic lateral sclerosis (ALS). We hypothesized that transoral motion-mode ultrasonography (TOMU) would be useful to ...

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to syna...
https://doi.org/10.1186/s13024-021-00433-8 10.1093/bioinformatics/btl140 10.1093/brain/awx024 10.1113/jphysiol.2004.077446 10.1523/JNEUROSCI.4101-05.2006 10.1002/ana.24731 10.1371/journal.pone.0085932 10.1038/35097565 10.1152/jn.00969.2010 10.1016/j.celrep.2017.09.028 10.1093/nar/gky1113 10.1002/stem.2388 10.1038/ncomms6999 10.1186/s40478-019-0797-0 10.1093/bioinformatics/bts635 10.1038/srep37968 10.1016/j.neuron.2017.11.028 10.1186/s40478-018-0579-0 10.1016/j.nbd.2013.06.005 10.1001/jamaneurol.2015.1872 10.1038/nrneurol.2016.140 10.7554/eLife.50333 10.1073/pnas.1405741111 10.1093/cercor/bhw185 10.1038/ncomms15132 10.1186/s40478-020-01030-4 10.1523/JNEUROSCI.5881-08.2009 10.1523/JNEUROSCI.0811-17.2017 10.1016/0896-6273(92)90075-O 10.1371/journal.pcbi.1004438 10.1093/bioinformatics/btt656 10.1523/JNEUROSCI.5410-13.2014 10.1113/JP270660 10.1016/j.clinph.2014.04.023 10.1111/ene.13295 10.1016/j.tins.2010.08.002 10.1016/j.celrep.2017.02.060 10.1523/JNEUROSCI.5231-04.2005 10.3109/21678421.2012.734520 10.1093/cercor/bhx301 10.1038/srep26181 10.1016/j.neuron.2015.11.018 10.1016/j.expneurol.2008.11.002 10.1038/nn.4065 10.1016/S0896-6273(00)80146-4 10.1093/cercor/bhu317 10.1126/scitranslmed.3007529 10.1002/mus.25047 10.1523/JNEUROSCI.0360-18.2018 10.1038/s41467-017-02729-0 10.1093/brain/awr355 10.1093/cercor/bhq152 10.1016/j.brainres.2018.02.011 10.1038/s41593-018-0080-x 10.1523/JNEUROSCI.1340-08.2008 10.1002/mus.20481 10.1093/brain/awn071 10.1001/jamaneurol.2015.2197 10.1016/j.celrep.2014.03.019 10.1136/jnnp-2012-304529 10.1016/0896-6273(94)90031-0 10.1038/nn.4257 10.1002/glia.23761
Molecular Neurodegeneration; Perkins EM, Burr K et. al.

Mar 5th, 2021 - Physiological disturbances in cortical network excitability and plasticity are established and widespread in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients, including those harbouring the C9ORF72 repeat expansion (C...

Evaluating person-centered factors associated with brain-computer interface access to a...
https://doi.org/10.1080/10400435.2021.1872737
Assistive Technology : the Official Journal of RESNA; Pitt KM, Brumberg JS

Mar 5th, 2021 - Current BCI-AAC systems largely utilize custom-made software and displays that may be unfamiliar to AAC stakeholders. Further, there is limited information available exploring the heterogenous profiles of individuals who may use BCI-AAC. Therefore...

Prevalence of pain in amyotrophic lateral sclerosis: a systematic review and meta-analy...
https://doi.org/10.1080/21678421.2021.1892765
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration; Hurwitz N, Radakovic R et. al.

Mar 4th, 2021 - Objectives: Physical pain is a known symptom in amyotrophic lateral sclerosis (ALS), but no systematically derived prevalence estimate is available. The aim of this study was to determine the pooled prevalence of pain in ALS, relative to its metho...

see more →

News  453 results

After a Decade of Lobbying, ALS Patients Gain Faster Access to Disability Payments
https://www.medscape.com/viewarticle/944474

Jan 20th, 2021 - Anita Baron first noticed something was wrong in August 2018, when she began to drool. Her dentist chalked it up to a problem with her jaw. Then her speech became slurred. She managed to keep her company, which offers financing to small businesses...

VA Study Finds More ALS Hospitalizations With Edaravone
https://www.staging.medscape.com/viewarticle/938926

Oct 14th, 2020 - NEW YORK (Reuters Health) - Amyotrophic lateral sclerosis (ALS) patients prescribed edaravone are hospitalized more frequently, a new surveillance study in U.S. military veterans shows. Patients on edaravone had significantly higher rates of all-c...

VA Study Finds More ALS Hospitalizations With Edaravone
https://www.medscape.com/viewarticle/938926

Oct 14th, 2020 - NEW YORK (Reuters Health) - Amyotrophic lateral sclerosis (ALS) patients prescribed edaravone are hospitalized more frequently, a new surveillance study in U.S. military veterans shows. Patients on edaravone had significantly higher rates of all-c...

Drug Combo Slows Functional Decline in ALS
https://www.staging.medscape.com/viewarticle/936885

Sep 2nd, 2020 - Treatment with a fixed-dose combination of sodium phenylbutyrate and taurursodiol (AMX0035, Amylyx Pharmaceuticals) slows the rate of decline in physical function in patients with amyotrophic lateral sclerosis (ALS), according to results of the ph...

Drug Combo Slows Functional Decline in ALS
https://www.medscape.com/viewarticle/936885

Sep 2nd, 2020 - Treatment with a fixed-dose combination of sodium phenylbutyrate and taurursodiol (AMX0035, Amylyx Pharmaceuticals) slows the rate of decline in physical function in patients with amyotrophic lateral sclerosis (ALS), according to results of the ph...

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Patient Education  19 results see all →