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About 435 results

ALLMedicine™ Multifocal Motor Neuropathy Center

Research & Reviews  156 results

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy
https://clinicaltrials.gov/ct2/show/NCT05225675

Jun 15th, 2022 - This is a phase 2, randomized, double-blinded, placebo-controlled, parallel-group, multicenter trial to evaluate the safety and efficacy of 2 dose regimens of ARGX-117 versus placebo, in participants with MMN previously stabilized with IVIg (intra...

Rituximab in chronic immune mediated neuropathies: a systematic review.
https://doi.org/10.1016/j.nmd.2022.05.013
Neuromuscular Disorders : NMD; Chaganti S, Hannaford A et. al.

Jun 8th, 2022 - Chronic immune mediated neuropathy is a heterogenous group of peripheral nerve diseases, encompassing chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), autoimmune nodopathy, multifocal motor neuropathy (MMN), and anti-myelin-associ...

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy
https://clinicaltrials.gov/ct2/show/NCT05405361

Jun 6th, 2022 - This trial is an extension of the antecedent trial ARGX-117-2002. It is a multicenter trial that has been designed to evaluate the long-term safety and tolerability, efficacy, immunogenicity, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ARG...

Neurofilament light chain and total tau in the differential diagnosis and prognostic ev...
https://doi.org/10.1111/ene.15428
European Journal of Neurology; Kmezic I, Samuelsson K et. al.

Jun 1st, 2022 - To investigate the diagnostic and prognostic value of axonal injury biomarkers in patients with inflammatory polyneuropathies. Neurofilament light chain (NfL) and total tau (T-tau) were measured in the cerebrospinal fluid (CSF) and plasma in 41 pa...

A Pilot Trial To Assess The Feasibility And Efficacy Of SCIG In Patients With MG Exacerbation (SCIG-MG)
https://clinicaltrials.gov/ct2/show/NCT02774239

May 31st, 2022 - This is a prospective open-label, uncontrolled, single-blind, pilot clinical trial. The primary objective is to assess the efficacy, safety, feasibility and tolerability of SCIG in patients with worsening MG. Study Rationale and Significance Subcu...

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Drugs  1 results see all →

Clinicaltrials.gov  14 results

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy
https://clinicaltrials.gov/ct2/show/NCT05225675

Jun 15th, 2022 - This is a phase 2, randomized, double-blinded, placebo-controlled, parallel-group, multicenter trial to evaluate the safety and efficacy of 2 dose regimens of ARGX-117 versus placebo, in participants with MMN previously stabilized with IVIg (intra...

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy
https://clinicaltrials.gov/ct2/show/NCT05405361

Jun 6th, 2022 - This trial is an extension of the antecedent trial ARGX-117-2002. It is a multicenter trial that has been designed to evaluate the long-term safety and tolerability, efficacy, immunogenicity, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ARG...

A Pilot Trial To Assess The Feasibility And Efficacy Of SCIG In Patients With MG Exacerbation (SCIG-MG)
https://clinicaltrials.gov/ct2/show/NCT02774239

May 31st, 2022 - This is a prospective open-label, uncontrolled, single-blind, pilot clinical trial. The primary objective is to assess the efficacy, safety, feasibility and tolerability of SCIG in patients with worsening MG. Study Rationale and Significance Subcu...

A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN)
https://clinicaltrials.gov/ct2/show/NCT05084053

May 6th, 2022 - The main aim of the study is to check for side effects from TAK-771, and to check how well TAK-771 controls symptoms in Japanese participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MM...

Role of High Frequency Ultrasound in Demyelinating Polyneuropathies
https://clinicaltrials.gov/ct2/show/NCT04978623

Aug 3rd, 2021 - The use of neuroimaging in the evaluation of neuromuscular pathologies is a promising and rapidly expandinf field. Among the different imaging techniques employed, nerve ultrasound is of particular interest given it's non invasivity, lack of side ...

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News  3 results

Corneal confocal microscopy deemed useful in immune-mediated neuropathies
https://www.mdedge.com/neurology/article/105721/pain/corneal-confocal-microscopy-deemed-useful-immune-mediated-neuropathies
Lucas Franki

Jan 11th, 2016 - Corneal confocal microscopy was effective at identifying and diagnosing subsets of chronic inflammatory demyelinating polyradiculoneuropathy and multifocal motor neuropathy, according to Dr. Mark Stettner and his associates.

Immune Globulin Approved for Multifocal Motor Neuropathy
https://www.medscape.com/viewarticle/766549

Jun 27th, 2012 - June 27, 2012 — Immune Globulin Infusion (Human), 10% (Gammagard Liquid, Baxter International, Inc), has been approved by the US Food and Drug Administration (FDA) as a treatment for multifocal motor neuropathy (MMN), making it the first immunoglo...

Update on Immune-Mediated Neuropathies
https://www.medscape.com/viewarticle/500812

Kieseier and colleagues present a review of the literature on immune-mediated neuropathies, emphasizing the immunopathologic mechanisms underlying these neuropathies. Immune-mediated neuropathies have received increasing attention in recent years ...

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