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About 245 results

ALLMedicine™ Stiff Person Syndrome Center

Research & Reviews  88 results

Stiff person syndrome spectrum disorders; more than meets the eye.
https://doi.org/10.1016/j.jneuroim.2022.577915
Journal of Neuroimmunology; Newsome SD, Johnson T

Jun 20th, 2022 - Stiff person syndrome spectrum disorders (SPSD) are a group of rare neuroimmunological disorders that often include painful spasms and rigidity. However, patients have highly heterogeneous signs and symptoms which may reflect different mechanistic...

Pediatric stiff limb syndrome with polyautoimmunity of anti-GAD-65, anti-islet cell, an...
https://doi.org/10.1016/j.jneuroim.2022.577865
Journal of Neuroimmunology; Nie DA, Abud A et. al.

Apr 26th, 2022 - We report an early childhood onset Stiff Limb Syndrome (SLS) in association with unusual polyautoimmunity of GAD-65, anti-islet cell, and Thyroid Peroxidase (TPO) autoantibodies, who has achieved a nearly complete neurological recovery following c...

Stiff-person Syndrome and GAD Antibody-spectrum Disorders: GABAergic Neuronal Excitabil...
https://doi.org/10.1007/s13311-022-01188-w 10.1111/epi.16888 10.1097/MD.0000000000025260 10.1212/WNL.0000000000011338 10.1212/WNL.0000000000011349 10.1177/1756286421997381
Neurotherapeutics : the Journal of the American Society F... Dalakas MC

Jan 28th, 2022 - Although antibodies against Glutamic Acid Decarboxylase (GAD) were originally associated with Stiff Person Syndrome (SPS), they now denote the "GAD antibody-spectrum disorders (GAD-SD)" that include Cerebellar Ataxia, Autoimmune Epilepsy, Limbic E...

Schwartz-Jampel Syndrome
https://emedicine.medscape.com/article/1172013-overview

Jan 6th, 2022 - Background Schwartz-Jampel syndrome (SJS) is a term now applied to 2 different inherited, autosomal recessive conditions, sometimes termed SJS type I and SJS type II. Both are very rare. SJS type I has 2 recognized subtypes, IA and IB, which are s...

Schwartz-Jampel Syndrome
https://emedicine.medscape.com/article/1172013-print

Jan 6th, 2022 - Background Schwartz-Jampel syndrome (SJS) is a term now applied to 2 different inherited, autosomal recessive conditions, sometimes termed SJS type I and SJS type II. Both are very rare. SJS type I has 2 recognized subtypes, IA and IB, which are s...

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Clinicaltrials.gov  3 results

Stem Cell Transplantation for Stiff Person Syndrome (SPS)
https://clinicaltrials.gov/ct2/show/NCT02282514

Jan 27th, 2021 - Pre-study Testing History and physical Electrocardiogram (EKG) Dobutamine stress echocardiogram High-resolution computed tomography of the chest (HRCT) Blood draw for laboratory tests- these tests will include a complete blood count, evaluating li...

Efficacy and Mechanism of Action of SCIg in Patients With Stiff Person Syndrome (SPS)
https://clinicaltrials.gov/ct2/show/NCT03829826

May 14th, 2019 - Study Design:This is a proof of concept observational prospective, open label, study on the safety, efficacy and convenience of treatment with SCIg study of 22 patients at Thomas Jefferson University Hospital. Two cohorts of patients within the to...

Rituximab to Treat Stiff Person Syndrome
https://clinicaltrials.gov/ct2/show/NCT00091897

Aug 31st, 2011 - This study will examine the safety, tolerability, and efficacy of the humanized monoclonal antibody Rituximab to induce a clinical and serological remission in patients with Stiff Person Syndrome (SPS) associated with high anti-GAD antibodies. Rit...

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News  7 results

Disability in Patients With Stiff Person Syndrome May Progress Faster Than Thought
https://www.mdedge.com/neurology/article/178566/rare-diseases/disability-patients-stiff-person-syndrome-may-progress-faster

Oct 31st, 2018 - WASHINGTON, DC—Stiff person syndrome leads to disability if therapy is not initiated early in the disease course, according to a prospective study presented at the 2018 Annual Meeting of the American Association of Neuromuscular & Electrodiagnosti.

NORD Awards Grants for Rare Disease Research
https://www.mdedge.com/clinicianreviews/article/134590/rare-diseases/nord-awards-grants-rare-disease-research

Mar 29th, 2017 - The National Organization for Rare Disorders (NORD) has awarded seven new research grants to fund rare disease research. These grants are in response to NORD’s 2016 Requests for Proposals.

October 21 Is Deadline for NORD Research Grant Abstracts
https://www.mdedge.com/neurology/article/116220/rare-diseases/october-21-deadline-nord-research-grant-abstracts

Oct 1st, 2016 - The deadline has been extended to October 21 to submit letters of intent and abstracts for National Organization for Rare Disorders (NORD) research grants for studies related to the following rare diseases: Alveolar capillary dysplasia with misali.

NORD Announces 2016 Grant Opportunities
https://www.mdedge.com/familymedicine/article/113266/rare-diseases/nord-announces-2016-grant-opportunities
Neurology Reviews;

Sep 1st, 2016 - NORD has announced its 2016 requests for proposals for research studies related to the following rare diseases: Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) Appendix cancer and pseudomyxoma peritonei (PMP) Autoim.

NORD Announces 2016 Grant Opportunities
https://www.mdedge.com/clinicianreviews/article/113266/rare-diseases/nord-announces-2016-grant-opportunities

Sep 1st, 2016 - NORD has announced its 2016 requests for proposals for research studies related to the following rare diseases: Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) Appendix cancer and pseudomyxoma peritonei (PMP) Autoim.

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