ALLMedicine™ Anticholinergic Toxicity Center

Sep 4th, 2021 - The incidence of anticholinergic syndrome due to second generation antihistamines is infrequently reported. Largely due to their decreased affinity for central nervous system (CNS) receptors, second generation antihistamines are rarely associated ...

May 25th, 2021 - While antipsychotic medications have long been associated with anticholinergic effects, asenapine has been purported to have no capacity for muscarinic cholinergic antagonism based on in vitro studies. Research in rat brain tissue has yielded diff...

Oct 31st, 2019 - Brugmansia suaveolens is the commonest species under the Solanacea ("Angels Trumpet" in English; "Attana" in Sinhalese) plant family in Sri Lanka. It contains alkaloids like scopolamine, atropine and hyoscyamine which can cause an anticholinergic ...

Dec 17th, 2014 - The anticholinergic toxidrome is well described and relatively common. Despite controversy, studies have shown that physostigmine is relatively safe and effective in reversing this toxidrome. We would expect toxicologists would be liberal in its u...

Aug 1st, 2014 - When administering physostigmine, atropine should be present at the bedside with airway equipment readily available as cholinergic effects may develop (specifically bronchospasm, bronchorrhea, or bradycardia). Dosing of physostigmine in adult pati.

Dec. 18, 2017: The FDA proposed a new, risk-based enforcement approach to drug products labeled as homeopathic. More here. Español What action did the FDA take? On October 23, 2010, the U.S. Food and Drug Administration (FDA) warned consumers to s...

Feb 24th, 2017 - Besides serotonin syndrome, other differential diagnoses were considered but excluded in this case. Neuroleptic malignant syndrome (NMS) is an idiopathic drug reaction to antipsychotics that has a presentation similar to that of serotonin syndrome...

Aug 1st, 2014 - When administering physostigmine, atropine should be present at the bedside with airway equipment readily available as cholinergic effects may develop (specifically bronchospasm, bronchorrhea, or bradycardia). Dosing of physostigmine in adult pati.

In your “Cases That Test Your Skills” article on Charles Bonnet syndrome (CBS) (Current Psychiatry, May 2003), the authors briefly mention substance-induced psychosis in the differential diagnosis of visual hallucinations. Ms.

Neuroleptic malignant syndrome (NMS) is an uncommon but by no means rare side effect of antipsychotics and other dopamine-blocking agents. This life-threatening form of drug-induced hyperthermia can be disastrous if missed, as initial treatment is.