ALLMedicine™ Anticholinergic Toxicity Center

Jun 29th, 2022 - Using multiple drugs with anticholinergic properties is common and might lead to cumulative anticholinergic toxicity and increased risk of cognitive impairment. Therefore, we sought to investigate the association between the Anticholinergic Cognit...

Feb 23rd, 2022 - Medication Summary Medical therapy consists of anticonvulsants, antitachydysrhythmics, sodium bicarbonate, physostigmine, and sedatives. The standard dose of physostigmine is 0.5-2 mg, given by slow iintravenous push (not to exceed 1 mg/min). Howe...

Feb 23rd, 2022 - Practice Essentials Anticholinergic syndrome (ACS) is produced by the inhibition of cholinergic neurotransmission at muscarinic receptor sites. It may follow the ingestion of a wide variety of prescription and over-the-counter medications. [1, 2, ...

Feb 23rd, 2022 - Practice Essentials Anticholinergic syndrome (ACS) is produced by the inhibition of cholinergic neurotransmission at muscarinic receptor sites. It may follow the ingestion of a wide variety of prescription and over-the-counter medications. [1, 2, ...

Feb 23rd, 2022 - Practice Essentials Anticholinergic syndrome (ACS) is produced by the inhibition of cholinergic neurotransmission at muscarinic receptor sites. It may follow the ingestion of a wide variety of prescription and over-the-counter medications.[1, 2, 3...

Jan 30th, 2023 - Recent Major Changes Section Warnings and Precautions, Falls (5.8) 02/2017 Boxed Warning Section Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic ...

Jan 27th, 2023 - Recent Major Changes Section Warnings and Precautions, Metabolic Changes (5.6) 12/2014 Boxed Warning Section Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Aripiprazole is not...

Jan 27th, 2023 - Recent Major Changes Section Warnings and Precautions, Metabolic Cnhages (5.6) 12/2014 Boxed Warning Section Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Aripiprazole is not...

Jan 23rd, 2023 - Boxed Warning Section Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death [see Warnings and Precautions (5.1)]....

Jan 17th, 2023 - SPL PRODUCT DATA ELEMENTS SECTION Chemical Structure Figure1 Figure2 Boxed Warning Section Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs ...

Nov 9th, 2021 - Emergency physicians need to be able to detect and manage antidepressant and benzodiazepine overdoses, Craig Smollin, MD, professor of clinical emergency medicine, University of California San Francisco (UCSF), said in a presentation at the Americ...

Dec. 18, 2017: The FDA proposed a new, risk-based enforcement approach to drug products labeled as homeopathic. More here. Español What action did the FDA take? On October 23, 2010, the U.S. Food and Drug Administration (FDA) warned consumers to s...

Feb 24th, 2017 - Besides serotonin syndrome, other differential diagnoses were considered but excluded in this case. Neuroleptic malignant syndrome (NMS) is an idiopathic drug reaction to antipsychotics that has a presentation similar to that of serotonin syndrome...

It is not clear whether a single 25-mg dose of meclizine—an H1-receptor antagonist—played a role in Mr. A’s psychotic symptoms.

Neuroleptic malignant syndrome (NMS) is an uncommon but by no means rare side effect of antipsychotics and other dopamine-blocking agents. This life-threatening form of drug-induced hyperthermia can be disastrous if missed, as initial treatment is.