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About 2,178 results

ALLMedicine™ Cerebral Amyloid Angiopathy Center

Research & Reviews  809 results

Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and ...
https://doi.org/10.1093/brain/awac178
Brain : a Journal of Neurology; Rabin JS, Nichols E et. al.

Jun 28th, 2022 - Accumulating data suggest that cerebrovascular disease contributes to Alzheimer's disease pathophysiology and progression toward dementia. Cerebral amyloid angiopathy is a form of cerebrovascular pathology that results from the build-up of β-amylo...

Noninvasive Antemortem Detection of Retinal Prions by a Fluorescent Tracer.
https://doi.org/10.3233/JAD-220314
Journal of Alzheimer's Disease : JAD; Aguilar-Calvo P, Sevillano AM et. al.

Jun 28th, 2022 - Neurodegenerative diseases are widespread yet challenging to diagnose and stage antemortem. As an extension of the central nervous system, the eye harbors retina ganglion cells vulnerable to degeneration, and visual symptoms are often an early man...

Vascular lesions and brain atrophy in Alzheimer's, vascular and mixed dementia: an opti...
https://doi.org/10.2174/1567205019666220620112831
Current Alzheimer Research; Matteo CR, Paolo V et. al.

Jun 22nd, 2022 - Vascular lesions may be a common finding also in Alzheimer's dementia, but their role on cognitive status is uncertain. to investigate their distribution in patients with Alzheimer's, vascular or mixed dementia and detect any distinctive neuroradi...

Evolution of Clinical-Pathological Correlations in Early-Onset Alzheimer's Disease Over...
https://doi.org/10.3233/JAD-220045
Journal of Alzheimer's Disease : JAD; Sarto J, Mayà G et. al.

Jun 21st, 2022 - Early onset Alzheimer's disease (EOAD) represents a diagnostic challenge and is associated with a high diagnostic delay and misdiagnosis. To describe clinical and pathological data from a pathologically confirmed EOAD cohort and evaluate evolving ...

Glymphatic dysfunction correlates with severity of small vessel disease and cognitive i...
https://doi.org/10.1111/ene.15450
European Journal of Neurology; Xu J, Su Y et. al.

Jun 18th, 2022 - Cerebral amyloid angiopathy (CAA) is characterized by β-amyloid deposition in cortical and leptomeningeal arterioles, which might result from glymphatic dysfunction. We aimed to explore glymphatic function in CAA using the non-invasive diffusion t...

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Clinicaltrials.gov  26 results

Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy
https://clinicaltrials.gov/ct2/show/NCT05394636

Jun 6th, 2022 - Cerebellar superficial siderosis (SS) has been recently reported to be present in about 10% of both hereditary (n=50) and sporadic (n=46) cerebral amyloid angiopathy (CAA) patients on 3T MRI using susceptibility-weighted imaging (SWI) in the major...

Cortical Superficial Siderosis and Risk of Recurrent Intracerebral Hemorrhage in Cerebral Amyloid Angiopathy.
https://clinicaltrials.gov/ct2/show/NCT03464344

Mar 16th, 2022 - Patients with acute lobar ICH fulfilling the Boston criteria for probable or possible CAA will be enrolled within 30 days after ICH onset. Brain MRI performed at baseline will be analyzed blinded to clinical data. Patients with presence of cSS wil...

ROSE-Longitudinal Assessment With Neuroimaging
https://clinicaltrials.gov/ct2/show/NCT05089331

Mar 8th, 2022 - The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neuroimaging cohort of ROSE to obtain long-term neuroimaging and identical assessments longitudinally to address critical questions regarding the progressive...

Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis Patients
https://clinicaltrials.gov/ct2/show/NCT05075798

Feb 11th, 2022 - Transthyretin amyloidosis (aTTR) initially described as a rare disease, became the most serious hereditary polyneuropathy of adult onset and family screening has made it possible to identify and follow up many asymptomatic patients and carriers of...

Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA)
https://clinicaltrials.gov/ct2/show/NCT05207475

Jan 26th, 2022 - CAA is a cerebrovascular disease caused by the deposition of β-amyloid in the walls of arteries, arterioles, and capillaries in the cerebral cortex and overlying leptomeninges. It is often associated with repeated lobar intracerebral hemorrhages, ...

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News  35 results

Brain Bleeds Double the Risk of Arterial Ischemic Events
https://www.medpagetoday.com/neurology/generalneurology/92386

May 3rd, 2021 - Survivors of intracerebral hemorrhage had three times the risk of ischemic stroke compared with the general population, and twice the risk of myocardial infarction (MI), an analysis of U.S. population-based cohort studies found. In a study of near...

Apathy Predicts Dementia; More COVID Neuro Findings; Parkinson's Immunotherapy
https://www.medpagetoday.com/neurology/generalneurology/87552

Jul 14th, 2020 - Apathy, but not depression, predicted dementia in cerebral small vessel disease. (Journal of Neurology, Neurosurgery & Psychiatry) Cerebral organoids grown from strands of hair from Down syndrome donors showed potential as an early drug testing pl...

Sleep Disturbance May Predict Rapid Cognitive Decline in AD
https://www.staging.medscape.com/viewarticle/931031

May 22nd, 2020 - Excessive sleep disturbances are linked to increased cognitive decline in patients with Alzheimer's disease (AD), new research suggests. Records from the National AD Coordinating Center (NACC) datasets for more than 400 patients with autopsy-confi...

Mixed ICH Patients at Higher Risk of Disability
https://www.medscape.com/viewarticle/913870

Jun 4th, 2019 - MILAN — Patients presenting with mixed intracranial hemorrhage (ICH) features on MRI — that is, ICH or microbleeds in both lobar and deep areas of the brain — are at higher risk for worse outcomes vs those with strictly lobar or deep ICH presentat...

Fast Five Quiz: Intracranial Hemorrhage
https://reference.medscape.com/viewarticle/909548_2

May 1st, 2019 - Although trauma is the most common cause of ICH, ICH can develop from nontraumatic etiologies. Hypertensive damage to blood vessel walls (eg, hypertension, eclampsia, drug abuse) is the most common cause of nontraumatic ICH. Other, less common non...

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Patient Education  1 results see all →