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About 725 results

ALLMedicine™ Anencephaly Center

Research & Reviews  335 results

First trimester naproxen exposure and outcome of pregnancy - A German case series.
https://doi.org/10.1016/j.reprotox.2021.05.006
Reproductive Toxicology (Elmsford, N.Y.); Hultzsch S, Paulus W et. al.

May 20th, 2021 - In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied. The objective of this analysis was to assess negative effects on pregnancy outcomes following naproxen exposure in the first tr...

Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126771
Proceedings of the National Academy of Sciences of the Un... Maniou E, Staddon MF et. al.

May 4th, 2021 - Gap closure is a common morphogenetic process. In mammals, failure to close the embryonic hindbrain neuropore (HNP) gap causes fatal anencephaly. We observed that surface ectoderm cells surrounding the mouse HNP assemble high-tension actomyosin pu...

The impact of anencephaly on parents: A mixed-methods study.
https://doi.org/10.1080/07481187.2021.1909669
Death Studies; Berry SN, Severtsen B et. al.

Apr 19th, 2021 - This study used a convergent parallel mixed-method design to explore the impact of an anencephalic pregnancy on parents. Twenty women and four men between 18-59 years old participated. Interview transcripts were analyzed using interpretive phenome...

Food Fortification with Folic Acid Prevents Spina Bifida and Anencephaly: A Need for Pa...
https://doi.org/10.1093/aje/kwab061
American Journal of Epidemiology; Martinez H, Pachón H et. al.

Mar 17th, 2021 - Modern epidemiology advocates context-specific evidence evaluation to support public health policy decisions, avoiding excessive reliance on experimental designs. We present the rationale for a paradigm shift in evaluation of the evidence derived ...

The Global Burden of Neural Tube Defects and Disparities in Neurosurgical Care.
https://doi.org/10.1016/j.wneu.2021.01.096
World Neurosurgery; Yacob A, Carr CJ et. al.

Feb 4th, 2021 - Despite the success of folic acid fortification programs, neural tube defects (NTDs) such as spina bifida, encephalocele, and anencephaly remain among the most substantial causes of childhood morbidity and mortality worldwide. Although these are c...

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Guidelines  2 results

Teratology Society position statement on surveillance and prevalence estimation of neural tu...
https://onlinelibrary.wiley.com/doi/full/10.1002/bdr2.1434
Kancherla, V.,et al

Dec 18th, 2018 - In this position statement, the Teratology Society acknowledges the value of accurate measurement of total prevalence of neural tube defects (NTDs) in the population to support prevention, and advocates for rigorous surveillance world‐wide. NTDs,.

Practice Bulletin No. 187: Neural Tube Defects.
https://doi.org/10.1097/AOG.0000000000002412
Obstetrics and Gynecology;

Nov 30th, 2017 - Neural tube defects (NTDs) are congenital structural abnormalities of the central nervous system and vertebral column. Neural tube defects may occur as an isolated malformation, in combination with other malformations, as part of a genetic syndrom...

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Clinicaltrials.gov  363 results

First trimester naproxen exposure and outcome of pregnancy - A German case series.
https://doi.org/10.1016/j.reprotox.2021.05.006
Reproductive Toxicology (Elmsford, N.Y.); Hultzsch S, Paulus W et. al.

May 20th, 2021 - In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied. The objective of this analysis was to assess negative effects on pregnancy outcomes following naproxen exposure in the first tr...

Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126771
Proceedings of the National Academy of Sciences of the Un... Maniou E, Staddon MF et. al.

May 4th, 2021 - Gap closure is a common morphogenetic process. In mammals, failure to close the embryonic hindbrain neuropore (HNP) gap causes fatal anencephaly. We observed that surface ectoderm cells surrounding the mouse HNP assemble high-tension actomyosin pu...

The impact of anencephaly on parents: A mixed-methods study.
https://doi.org/10.1080/07481187.2021.1909669
Death Studies; Berry SN, Severtsen B et. al.

Apr 19th, 2021 - This study used a convergent parallel mixed-method design to explore the impact of an anencephalic pregnancy on parents. Twenty women and four men between 18-59 years old participated. Interview transcripts were analyzed using interpretive phenome...

Food Fortification with Folic Acid Prevents Spina Bifida and Anencephaly: A Need for Pa...
https://doi.org/10.1093/aje/kwab061
American Journal of Epidemiology; Martinez H, Pachón H et. al.

Mar 17th, 2021 - Modern epidemiology advocates context-specific evidence evaluation to support public health policy decisions, avoiding excessive reliance on experimental designs. We present the rationale for a paradigm shift in evaluation of the evidence derived ...

The Global Burden of Neural Tube Defects and Disparities in Neurosurgical Care.
https://doi.org/10.1016/j.wneu.2021.01.096
World Neurosurgery; Yacob A, Carr CJ et. al.

Feb 4th, 2021 - Despite the success of folic acid fortification programs, neural tube defects (NTDs) such as spina bifida, encephalocele, and anencephaly remain among the most substantial causes of childhood morbidity and mortality worldwide. Although these are c...

see more →

News  23 results

Consultation on Fortifying Flour With Folic Acid 
https://www.medscape.com/viewarticle/902737

Oct 22nd, 2018 - The Government plans to consult on the mandatory fortification of flour with folic acid in a move to reduce birth defects. The consultation will start early next year and will look at the evidence around folic acid fortification as well as its pra...

Birth Defects Tied to Low Carb Diets (ScienceDaily)
https://www.medpagetoday.com/obgyn/pregnancy/70753

Jan 25th, 2018 - During pregnancy, low- and no-carbohydrate diets may not be a good choice, ScienceDaily reported. Originally published in the Birth Defects Research journal, the study found low-carb diets throughout pregnancy were associated with a 30% higher ris...

Is It Ethical to Use Anencephalic Newborns for Organ Donation?
https://www.staging.medscape.com/viewarticle/876605

Mar 9th, 2017 - Hi. I am Art Caplan at New York University's Langone Medical Center, Division of Medical Ethics. There have been a lot of headlines lately about a very brave mom who is carrying a child with a terrible birth defect. The defect is called anencephal...

Is It Ethical to Use Anencephalic Newborns for Organ Donation?
https://www.medscape.com/viewarticle/876605

Mar 9th, 2017 - Hi. I am Art Caplan at New York University's Langone Medical Center, Division of Medical Ethics. There have been a lot of headlines lately about a very brave mom who is carrying a child with a terrible birth defect. The defect is called anencephal...

WHO Issues Folate Recommendations for Women
https://www.medscape.com/viewarticle/843681

Apr 23rd, 2015 - Optimal red blood cell (RBC) folate concentrations should exceed 400 ng/mL in women of reproductive age to prevent neural tube defects (NTDs), according to World Health Organization (WHO) guidelines described in an article published in the April 2...

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Patient Education  2 results see all →