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About 194 results

ALLMedicine™ Infantile Spasm Center

Research & Reviews  91 results

Quality of life at 6 years in children treated for West syndrome with hormonal therapy.
https://doi.org/10.1016/j.yebeh.2021.107974
Epilepsy & Behavior : E&B; Wanigasinghe J, Arambepola C et. al.

May 4th, 2021 - West syndrome is a severe epileptic encephalopathy occurring in infancy. Majority of affected children suffer from poor epilepsy control in later life and are dependent on care-givers for daily living. There is no previous study evaluating the Qua...

Epilepsy Outcome at Four Years in a Randomized Clinical Trial Comparing Oral Prednisolo...
https://doi.org/10.1016/j.pediatrneurol.2021.01.008
Pediatric Neurology; Wanigasinghe J, Arambepola C et. al.

Apr 9th, 2021 - This article explores the role of initial treatment on control of spasms and other epilepsies at four years in children previously treated for West syndrome. The Sri Lanka Infantile Spasm Study is a prospective clinical trial evaluating response t...

Efficacy of the ketogenic diet on ACTH- or corticosteroid-resistant infantile spasm: a ...
https://doi.org/10.1684/epd.2021.1256
Epileptic Disorders : International Epilepsy Journal With... Zhang J, Chen G et. al.

Mar 27th, 2021 - To determine the efficacy of ketogenic diet (KD) therapy on adrenocorticotropic hormone- (ACTH) or corticosteroid-resistant infantile spasm (IS), and identify relevant associated factors. A prospective controlled study was undertaken at 10 tertiar...

A case of TSC2-PKD1 contiguous deletion syndrome: Clinical features and effective treat...
https://doi.org/10.1002/jdn.10088
International Journal of Developmental Neuroscience : The... Pan X, Yang C et. al.

Jan 9th, 2021 - Polycystic kidney disease with Tuberous sclerosis is a disease caused by the deletions of the TSC2-PKD1 gene. The disease is rarely reported and the characterized manifestation is severe polycystic kidney growth. The diagnosis can be made by molec...

Cost-effectiveness of adrenocorticotropic hormone versus oral steroids for infantile sp...
https://doi.org/10.1111/epi.16799
Epilepsia Sánchez Fernández I, Amengual-Gual M et. al.

Jan 8th, 2021 - To compare the effectiveness and cost-effectiveness of adrenocorticotropic hormone (ACTH) and oral steroids as first-line treatment for infantile spasm resolution, we performed a systematic review, meta-analysis, and cost-effectiveness study. A de...

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Drugs  1 results see all →

Clinicaltrials.gov  97 results

Quality of life at 6 years in children treated for West syndrome with hormonal therapy.
https://doi.org/10.1016/j.yebeh.2021.107974
Epilepsy & Behavior : E&B; Wanigasinghe J, Arambepola C et. al.

May 4th, 2021 - West syndrome is a severe epileptic encephalopathy occurring in infancy. Majority of affected children suffer from poor epilepsy control in later life and are dependent on care-givers for daily living. There is no previous study evaluating the Qua...

Epilepsy Outcome at Four Years in a Randomized Clinical Trial Comparing Oral Prednisolo...
https://doi.org/10.1016/j.pediatrneurol.2021.01.008
Pediatric Neurology; Wanigasinghe J, Arambepola C et. al.

Apr 9th, 2021 - This article explores the role of initial treatment on control of spasms and other epilepsies at four years in children previously treated for West syndrome. The Sri Lanka Infantile Spasm Study is a prospective clinical trial evaluating response t...

Efficacy of the ketogenic diet on ACTH- or corticosteroid-resistant infantile spasm: a ...
https://doi.org/10.1684/epd.2021.1256
Epileptic Disorders : International Epilepsy Journal With... Zhang J, Chen G et. al.

Mar 27th, 2021 - To determine the efficacy of ketogenic diet (KD) therapy on adrenocorticotropic hormone- (ACTH) or corticosteroid-resistant infantile spasm (IS), and identify relevant associated factors. A prospective controlled study was undertaken at 10 tertiar...

A case of TSC2-PKD1 contiguous deletion syndrome: Clinical features and effective treat...
https://doi.org/10.1002/jdn.10088
International Journal of Developmental Neuroscience : The... Pan X, Yang C et. al.

Jan 9th, 2021 - Polycystic kidney disease with Tuberous sclerosis is a disease caused by the deletions of the TSC2-PKD1 gene. The disease is rarely reported and the characterized manifestation is severe polycystic kidney growth. The diagnosis can be made by molec...

Cost-effectiveness of adrenocorticotropic hormone versus oral steroids for infantile sp...
https://doi.org/10.1111/epi.16799
Epilepsia Sánchez Fernández I, Amengual-Gual M et. al.

Jan 8th, 2021 - To compare the effectiveness and cost-effectiveness of adrenocorticotropic hormone (ACTH) and oral steroids as first-line treatment for infantile spasm resolution, we performed a systematic review, meta-analysis, and cost-effectiveness study. A de...

see more →

News  5 results

High infantile spasm risk should contraindicate sodium channel blocker antiepileptics
https://www.mdedge.com/neurology/epilepsyresourcecenter/article/214010/epilepsy-seizures/high-infantile-spasm-risk-should?channel=53
M. Alexander Otto

Dec 10th, 2019 - BALTIMORE – Sodium channel blocker antiepileptic drugs increase the risk of infantile spasms sevenfold in children with Down syndrome, tuberous sclerosis complex, hypoxic-ischemic encephalopathy, and other nonsyndromic epilepsy conditions with inf.

Impact of Hypsarrhythmia on Infantile Spasm Therapy
https://www.mdedge.com/neurology/epilepsyresourcecenter/article/155487/impact-hypsarrhythmia-infantile-spasm-therapy
Demarest ST, Shellhaas RA et. al.

Jan 4th, 2018 - Infants experiencing spasms will likely respond to standard first-line treatment, whether or not they also have hypsarrhythmia, according to a multicenter study of the National Infantile Spasms Consortium. The investigation included infants betwee.

ACTH and other standard treatments prove best for infantile spasms
https://www.mdedge.com/neurology/article/153694/pediatrics/acth-and-other-standard-treatments-prove-best-infantile-spasms
Eli Zimmerman

Dec 7th, 2017 - WASHINGTON – Standard infantile spasm therapies such as adrenocorticotropic hormone appear to be significantly more effective than nonstandard therapies, according to a prospective study presented at the annual meeting of the American Epilepsy Soc.

New Childhood Epilepsy Genes Discovered
https://www.medscape.com/viewarticle/809513

Aug 14th, 2013 - Using a cutting-edge strategy called exome sequencing to search for de novo mutations, researchers have found genetic defects that might cause infantile spasm and Lennox-Gastaut syndrome (LGS), 2 devastating childhood epileptic encephalopathies. E...

New Childhood Epilepsy Genes Discovered
https://www.staging.medscape.com/viewarticle/809513

Aug 14th, 2013 - Using a cutting-edge strategy called exome sequencing to search for de novo mutations, researchers have found genetic defects that might cause infantile spasm and Lennox-Gastaut syndrome (LGS), 2 devastating childhood epileptic encephalopathies. E...

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