ALLMedicine™ Down Syndrome Center
Research & Reviews 3,612 results
https://doi.org/10.1186/s12887-022-03450-8 10.1542/peds.2011-1605 10.1136/adc.2006.104638 10.1007/s11899-016-0338-x 10.1002/ajmg.a.31442 10.1002/ajmg.1320460509 10.1111/j.1399-0004.1996.tb04318.x 10.18233/APM37NO4PP246-249 10.1016/s1696-2818(04)71658-3 10.3109/08880019609030827
BMC Pediatrics; García de la Puente S, Flores-Arizmendi KA et. al.
Jul 2nd, 2022 - Down syndrome is associated with various congenital anomalies and metabolic alterations such as hematological alterations. Values for the major hematological indicators vary with age and sex, but these values have not been described for Mexican ch...
https://doi.org/10.1097/PEP.0000000000000924
Pediatric Physical Therapy : the Official Publication of ... Fiss AL, Ebert C
Jul 2nd, 2022 - Commentary on "The Journey: Parental Expectations and Perceptions of Therapy Services for Children With Down Syndrome".|2022|Fiss AL,Ebert C,|
https://clinicaltrials.gov/ct2/show/NCT01950624
Jul 1st, 2022 - Objective: The development of a patient registry for Down syndrome (DS) was identified as a priority in the 2007 Down Syndrome Research Plan. Under the auspices of the Down Syndrome Consortium, founded in 2011 as a public-private partnership betwe...
https://clinicaltrials.gov/ct2/show/NCT03914625
Jul 1st, 2022 - PRIMARY OBJECTIVES: I. To determine in a randomized manner if the addition of 2 cycles of blinatumomab to standard therapy improves disease-free survival (DFS) in patients with standard risk (SR) B-ALL and higher risk features (SR-High), and patie...
https://doi.org/10.5588/ijtld.22.0192
The International Journal of Tuberculosis and Lung Diseas... Parisini A, Boni S et. al.
Jul 1st, 2022 - Down Syndrome and COVID-19: not always a poor prognosis.|2022|Parisini A,Boni S,Vacca EB,Del Puente F,Feasi M,|complications,diagnosis,
Guidelines 13 results
https://doi.org/10.1001/jama.2020.17024
JAMA Tsou AY, Bulova P et. al.
Oct 21st, 2020 - Down syndrome is the most common chromosomal condition, and average life expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite the unique clinical comorbidities among adults with Down syndrome, there are no cli...
https://doi.org/10.1016/j.jogc.2017.06.013
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Chitayat D, Langlois S et. al.
Sep 2nd, 2017 - To develop a Canadian consensus document on maternal screening for fetal aneuploidy (e.g., Down syndrome and trisomy 18) in singleton pregnancies. Pregnancy screening for fetal aneuploidy started in the mid 1960s, using maternal age as the screeni...
https://doi.org/10.1016/j.jogc.2017.06.015
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Audibert F, Gagnon A
Sep 2nd, 2017 - To provide a Canadian consensus document with recommendations on prenatal screening for and diagnosis of fetal aneuploidy (e.g., Down syndrome and trisomy 18) in twin pregnancies. The process of prenatal screening and diagnosis in twin pregnancies...
https://doi.org/10.1097/AOG.0000000000001438
Obstetrics and Gynecology;
Apr 23rd, 2016 - Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a pat...
https://doi.org/10.1097/AOG.0000000000001405
Obstetrics and Gynecology;
Mar 5th, 2016 - Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a pat...
Clinicaltrials.gov 253 results
https://clinicaltrials.gov/ct2/show/NCT01950624
Jul 1st, 2022 - Objective: The development of a patient registry for Down syndrome (DS) was identified as a priority in the 2007 Down Syndrome Research Plan. Under the auspices of the Down Syndrome Consortium, founded in 2011 as a public-private partnership betwe...
https://clinicaltrials.gov/ct2/show/NCT03914625
Jul 1st, 2022 - PRIMARY OBJECTIVES: I. To determine in a randomized manner if the addition of 2 cycles of blinatumomab to standard therapy improves disease-free survival (DFS) in patients with standard risk (SR) B-ALL and higher risk features (SR-High), and patie...
https://clinicaltrials.gov/ct2/show/NCT02883049
Jun 30th, 2022 - PRIMARY OBJECTIVES: I. To determine if the administration of post-Induction age-adjusted intrathecal triple therapy (ITT) on a Modified Berlin-Frankfurt-Munster (MBFM) interim maintenance high-dose methotrexate (IMHDM) backbone will improve 5-year...
https://clinicaltrials.gov/ct2/show/NCT03342014
Jun 24th, 2022 - Introduction: Preeclampsia (PE) and intrauterine growth restriction (IUGR) are two major pregnancy complications, related to a chronic utero-placental hypoperfusion. Nowadays, there isn't a screening or diagnostic test in clinic for utero-placenta...
https://clinicaltrials.gov/ct2/show/NCT05312177
Jun 22nd, 2022 - We will conduct a multicenter cohort study, ancillary to the Pediatric Heart Network (PHN) Residual Lesion Score (RLS) study, to investigate determinants of ND and behavioral outcomes in children with DS, focusing on the role of CHD surgery. We wi...
News 253 results
https://www.medscape.com/viewarticle/976060
Jun 22nd, 2022 - It's rare for a child to die after a tonsillectomy, but children who die are more likely to have a complex chronic condition such as cerebral palsy or Down syndrome, according to a retrospective cohort study published in JAMA. "Among children unde...
https://www.medscape.com/viewarticle/974302
May 19th, 2022 - When you speak to Santiaga Nunez, right away, you can sense her deep and unwavering devotion to her son, Lloyd Tyler Rochez, born in 2002 with trisomy 13, a genetic disorder that can involve severe learning problems and health woes that affect n...
https://www.medscape.com/viewarticle/974222
May 18th, 2022 - Marthe Gautier, a French physician who was involved in the discovery of the extra chromosome that causes Down syndrome, died on Saturday, April 30. She was 96. This is an opportunity for us to look back and reflect on this discovery and the key ro...
https://www.medscape.com/viewarticle/972846
Apr 27th, 2022 - Upper airway hypoglossal nerve stimulation is safe and effective in adolescents with Down syndrome and severe persistent obstructive sleep apnea (OSA) occurring after adenotonsillectomy, and who couldn't tolerate positive airway pressure, early re...
https://www.medpagetoday.com/surgery/otolaryngology/98390
Apr 25th, 2022 - Upper airway stimulation appeared safe and effective in improving severe persistent obstructive sleep apnea (OSA) in adolescents with Down syndrome, a small multi-center cohort study found. In this first study to evaluate upper airway hypoglossal ...