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About 10,383 results

ALLMedicine™ Down Syndrome Center

Research & Reviews  3,612 results

Blood cytology in children with down syndrome.
https://doi.org/10.1186/s12887-022-03450-8 10.1542/peds.2011-1605 10.1136/adc.2006.104638 10.1007/s11899-016-0338-x 10.1002/ajmg.a.31442 10.1002/ajmg.1320460509 10.1111/j.1399-0004.1996.tb04318.x 10.18233/APM37NO4PP246-249 10.1016/s1696-2818(04)71658-3 10.3109/08880019609030827
BMC Pediatrics; García de la Puente S, Flores-Arizmendi KA et. al.

Jul 2nd, 2022 - Down syndrome is associated with various congenital anomalies and metabolic alterations such as hematological alterations. Values for the major hematological indicators vary with age and sex, but these values have not been described for Mexican ch...

Commentary on "The Journey: Parental Expectations and Perceptions of Therapy Services f...
https://doi.org/10.1097/PEP.0000000000000924
Pediatric Physical Therapy : the Official Publication of ... Fiss AL, Ebert C

Jul 2nd, 2022 - Commentary on "The Journey: Parental Expectations and Perceptions of Therapy Services for Children With Down Syndrome".|2022|Fiss AL,Ebert C,|

DS-Connect {TM}: The Down Syndrome Registry
https://clinicaltrials.gov/ct2/show/NCT01950624

Jul 1st, 2022 - Objective: The development of a patient registry for Down syndrome (DS) was identified as a priority in the 2007 Down Syndrome Research Plan. Under the auspices of the Down Syndrome Consortium, founded in 2011 as a public-private partnership betwe...

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
https://clinicaltrials.gov/ct2/show/NCT03914625

Jul 1st, 2022 - PRIMARY OBJECTIVES: I. To determine in a randomized manner if the addition of 2 cycles of blinatumomab to standard therapy improves disease-free survival (DFS) in patients with standard risk (SR) B-ALL and higher risk features (SR-High), and patie...

Down Syndrome and COVID-19: not always a poor prognosis.
https://doi.org/10.5588/ijtld.22.0192
The International Journal of Tuberculosis and Lung Diseas... Parisini A, Boni S et. al.

Jul 1st, 2022 - Down Syndrome and COVID-19: not always a poor prognosis.|2022|Parisini A,Boni S,Vacca EB,Del Puente F,Feasi M,|complications,diagnosis,

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Guidelines  13 results

Medical Care of Adults With Down Syndrome: A Clinical Guideline.
https://doi.org/10.1001/jama.2020.17024
JAMA Tsou AY, Bulova P et. al.

Oct 21st, 2020 - Down syndrome is the most common chromosomal condition, and average life expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite the unique clinical comorbidities among adults with Down syndrome, there are no cli...

No. 261-Prenatal Screening for Fetal Aneuploidy in Singleton Pregnancies.
https://doi.org/10.1016/j.jogc.2017.06.013
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Chitayat D, Langlois S et. al.

Sep 2nd, 2017 - To develop a Canadian consensus document on maternal screening for fetal aneuploidy (e.g., Down syndrome and trisomy 18) in singleton pregnancies. Pregnancy screening for fetal aneuploidy started in the mid 1960s, using maternal age as the screeni...

No. 262-Prenatal Screening for and Diagnosis of Aneuploidy in Twin Pregnancies.
https://doi.org/10.1016/j.jogc.2017.06.015
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Audibert F, Gagnon A

Sep 2nd, 2017 - To provide a Canadian consensus document with recommendations on prenatal screening for and diagnosis of fetal aneuploidy (e.g., Down syndrome and trisomy 18) in twin pregnancies. The process of prenatal screening and diagnosis in twin pregnancies...

Practice Bulletin No. 162 Summary: Prenatal Diagnostic Testing for Genetic Disorders.
https://doi.org/10.1097/AOG.0000000000001438
Obstetrics and Gynecology;

Apr 23rd, 2016 - Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a pat...

Practice Bulletin No. 162: Prenatal Diagnostic Testing for Genetic Disorders.
https://doi.org/10.1097/AOG.0000000000001405
Obstetrics and Gynecology;

Mar 5th, 2016 - Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a pat...

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Clinicaltrials.gov  253 results

DS-Connect {TM}: The Down Syndrome Registry
https://clinicaltrials.gov/ct2/show/NCT01950624

Jul 1st, 2022 - Objective: The development of a patient registry for Down syndrome (DS) was identified as a priority in the 2007 Down Syndrome Research Plan. Under the auspices of the Down Syndrome Consortium, founded in 2011 as a public-private partnership betwe...

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
https://clinicaltrials.gov/ct2/show/NCT03914625

Jul 1st, 2022 - PRIMARY OBJECTIVES: I. To determine in a randomized manner if the addition of 2 cycles of blinatumomab to standard therapy improves disease-free survival (DFS) in patients with standard risk (SR) B-ALL and higher risk features (SR-High), and patie...

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations
https://clinicaltrials.gov/ct2/show/NCT02883049

Jun 30th, 2022 - PRIMARY OBJECTIVES: I. To determine if the administration of post-Induction age-adjusted intrathecal triple therapy (ITT) on a Modified Berlin-Frankfurt-Munster (MBFM) interim maintenance high-dose methotrexate (IMHDM) backbone will improve 5-year...

First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography
https://clinicaltrials.gov/ct2/show/NCT03342014

Jun 24th, 2022 - Introduction: Preeclampsia (PE) and intrauterine growth restriction (IUGR) are two major pregnancy complications, related to a chronic utero-placental hypoperfusion. Nowadays, there isn't a screening or diagnostic test in clinic for utero-placenta...

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)
https://clinicaltrials.gov/ct2/show/NCT05312177

Jun 22nd, 2022 - We will conduct a multicenter cohort study, ancillary to the Pediatric Heart Network (PHN) Residual Lesion Score (RLS) study, to investigate determinants of ND and behavioral outcomes in children with DS, focusing on the role of CHD surgery. We wi...

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News  253 results

Deaths Rare in Tonsillectomy, but Some Children at More Risk
https://www.medscape.com/viewarticle/976060

Jun 22nd, 2022 - It's rare for a child to die after a tonsillectomy, but children who die are more likely to have a complex chronic condition such as cerebral palsy or Down syndrome, according to a retrospective cohort study published in JAMA. "Among children unde...

Meet a Miracle: Man With Trisomy 13 to Celebrate 20th Birthday
https://www.medscape.com/viewarticle/974302

May 19th, 2022 -   When you speak to Santiaga Nunez, right away, you can sense her deep and unwavering devotion to her son, Lloyd Tyler Rochez, born in 2002 with trisomy 13, a genetic disorder that can involve severe learning problems and health woes that affect n...

Marthe Gautier, 'Forgotten' Discoverer of Trisomy 21, Dies
https://www.medscape.com/viewarticle/974222

May 18th, 2022 - Marthe Gautier, a French physician who was involved in the discovery of the extra chromosome that causes Down syndrome, died on Saturday, April 30. She was 96. This is an opportunity for us to look back and reflect on this discovery and the key ro...

Implant May Alleviate Sleep Apnea in Teens With Down Syndrome
https://www.medscape.com/viewarticle/972846

Apr 27th, 2022 - Upper airway hypoglossal nerve stimulation is safe and effective in adolescents with Down syndrome and severe persistent obstructive sleep apnea (OSA) occurring after adenotonsillectomy, and who couldn't tolerate positive airway pressure, early re...

Upper Airway Stimulation Helps Sleep Apnea in Teens With Down Syndrome
https://www.medpagetoday.com/surgery/otolaryngology/98390

Apr 25th, 2022 - Upper airway stimulation appeared safe and effective in improving severe persistent obstructive sleep apnea (OSA) in adolescents with Down syndrome, a small multi-center cohort study found. In this first study to evaluate upper airway hypoglossal ...

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Patient Education  22 results see all →