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About 115 results

ALLMedicine™ Infantile Spasm Center

Research & Reviews  37 results

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents
https://clinicaltrials.gov/ct2/show/NCT05126914

Nov 19th, 2021 - Rare epilepsies as a whole account for 20-30% of epilepsies, but knowledge about prognostic factors is currently limited. This means that it is difficult to provide adequate information to families at diagnosis and during follow-up. Prognostic fac...

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm
https://clinicaltrials.gov/ct2/show/NCT04302116

Aug 25th, 2021 - Infantile spasms are recognized as epileptic encephalopathy which include the hypsarrhythmia or variants electroencephalographic (EEG) features and psychomotor regression. Various underlying conditions are associated with the infantile spasm inclu...

Quality of life at 6 years in children treated for West syndrome with hormonal therapy.
https://doi.org/10.1016/j.yebeh.2021.107974
Epilepsy & Behavior : E&B; Wanigasinghe J, Arambepola C et. al.

May 5th, 2021 - West syndrome is a severe epileptic encephalopathy occurring in infancy. Majority of affected children suffer from poor epilepsy control in later life and are dependent on care-givers for daily living. There is no previous study evaluating the Qua...

Epilepsy Outcome at Four Years in a Randomized Clinical Trial Comparing Oral Prednisolo...
https://doi.org/10.1016/j.pediatrneurol.2021.01.008
Pediatric Neurology; Wanigasinghe J, Arambepola C et. al.

Apr 10th, 2021 - This article explores the role of initial treatment on control of spasms and other epilepsies at four years in children previously treated for West syndrome. The Sri Lanka Infantile Spasm Study is a prospective clinical trial evaluating response t...

Efficacy of the ketogenic diet on ACTH- or corticosteroid-resistant infantile spasm: a ...
https://doi.org/10.1684/epd.2021.1256
Epileptic Disorders : International Epilepsy Journal With... Zhang J, Chen G et. al.

Mar 28th, 2021 - To determine the efficacy of ketogenic diet (KD) therapy on adrenocorticotropic hormone- (ACTH) or corticosteroid-resistant infantile spasm (IS), and identify relevant associated factors. A prospective controlled study was undertaken at 10 tertiar...

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Drugs  1 results see all →

Clinicaltrials.gov  2 results

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents
https://clinicaltrials.gov/ct2/show/NCT05126914

Nov 19th, 2021 - Rare epilepsies as a whole account for 20-30% of epilepsies, but knowledge about prognostic factors is currently limited. This means that it is difficult to provide adequate information to families at diagnosis and during follow-up. Prognostic fac...

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm
https://clinicaltrials.gov/ct2/show/NCT04302116

Aug 25th, 2021 - Infantile spasms are recognized as epileptic encephalopathy which include the hypsarrhythmia or variants electroencephalographic (EEG) features and psychomotor regression. Various underlying conditions are associated with the infantile spasm inclu...

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News  6 results

Smartphone Diagnosis in Infant Seizures Could Be Highly Effective
https://www.medscape.com/viewarticle/971173

Apr 27th, 2022 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner, reporting from the American Epilepsy Society meeting. Today, I have the pleasure of speaking with Dr Chethan Rao, a child and adolescent ...

EEG surveillance, preseizure treatment prevents TSC epilepsy, cognitive loss
https://www.mdedge.com/neurology/article/214984/epilepsy-seizures/eeg-surveillance-preseizure-treatment-prevents-tsc
M. Alexander Otto

Jan 3rd, 2020 - BALTIMORE – Monitoring children who have tuberous sclerosis with EEG and treating them with vigabatrin (Sabril) at the first sign of preseizure abnormalities, rather than the usual practice of no surveillance and waiting until they have seizures,.

New Childhood Epilepsy Genes Discovered
https://www.medscape.com/viewarticle/809513

Aug 15th, 2013 - Using a cutting-edge strategy called exome sequencing to search for de novo mutations, researchers have found genetic defects that might cause infantile spasm and Lennox-Gastaut syndrome (LGS), 2 devastating childhood epileptic encephalopathies. E...

New Childhood Epilepsy Genes Discovered
https://www.staging.medscape.com/viewarticle/809513

Aug 15th, 2013 - Using a cutting-edge strategy called exome sequencing to search for de novo mutations, researchers have found genetic defects that might cause infantile spasm and Lennox-Gastaut syndrome (LGS), 2 devastating childhood epileptic encephalopathies. E...

Infantile Spasms Guideline Encourages Early Diagnosis, Treatment
https://www.mdedge.com/neurology/article/54860/pediatrics/infantile-spasms-guideline-encourages-early-diagnosis-treatment
Sharon Worcester

Jun 12th, 2012 - Early diagnosis and treatment of infantile spasms, particularly with adrenocorticotropic hormone, may lead to improved long-term developmental outcomes, according to an updated guideline from the American Academy of Neurology and the Child Neurolo.

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