ALLMedicine™ Neonatal Seizures Center

Jun 9th, 2022 - Neonatal seizures are one of the most challenging problems for experts across the globe. Although there is no consensus on the "ideal" treatment of neonatal seizures, phenobarbitone has been the drug of choice for decades. Unfortunately, although ...

Jun 9th, 2022 - Electrographic seizures and abnormal background activity in the neonatal electroencephalogram (EEG) may differentiate between harmful versus benign brain insults. Using two animal models of neonatal seizures, electrical activity was recorded in fr...

May 12th, 2022 - To evaluate whether children born to women who use serotonergic antidepressants during pregnancy have higher risk of neonatal seizures and epilepsy. We used Swedish register-based data to examine associations between maternal-reported use of selec...

May 8th, 2022 - A recent Phase II randomized, controlled trial of bumetanide as an adjunctive treatment for neonatal seizures showed a robust efficacy signal and no evidence of toxicity. Concerns regarding bumetanide as an adjunctive anticonvulsant are addressed ...

May 8th, 2022 - In his editorial, Kevin Staley criticizes our recent work demonstrating the lack of effect of bumetanide in a novel model of neonatal seizures. The main points in our response are that (1) our work is on an asphyxia model, not one on "hypercarbia ...

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

May 4th, 2022 - Neonatal seizures due to brain injury (acute provoked seizures) are associated with high risk of post-neonatal epilepsy. Although clinical risk factors can help predict which children are at highest risk for epilepsy, little is known about how gen...

Apr 27th, 2022 - Our goals are to evaluate the effectiveness of the Epilog device in identification of neonates who are at risk for seizures and need formal EEG monitoring or cooling. The current process for these patients would be transfer from Rochester Methodis...

Apr 1st, 2022 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The incidence of neonatal seizures is variable based on gestational age. The etiology of seizures...

Apr 1st, 2022 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The promoted treatment of seizures can limit the secondary injury to the brain and positively aff...

Feb 25th, 2022 - An Overview on neonatal seizures in neonatal intensive care unit of Assuit University Children's hospital , a cross sectional study. The aim of this study is to evaluate the clinical seizures during the neonatal period and its prevalence

Jun 2nd, 2021 - NEW YORK (Reuters Health) - For most newborns with acute symptomatic seizures, doctors can safely stop antiseizure medications before hospital discharge, without worse neurodevelopmental outcomes or increased risk of epilepsy, a new study suggests...

Mar 1st, 2021 - (Reuters Health) - Infants with neonatal opioid withdrawal syndrome (NOWS) may have shorter hospital stays and spend less time on morphine when they receive phenobarbital as secondary therapy, a U.S. study suggests. Researchers examined data on 56...

Oct 28th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that...

Oct 27th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that.

Feb 25th, 2020 - Authors: Shavonne L. Massey, MD and Hannah C.