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About 1,233 results

ALLMedicine™ Neonatal Seizures Center

Research & Reviews  428 results

Levetiracetam or Phenobarbitone as a First-Line Anticonvulsant in Asphyxiated Term Newb...
https://doi.org/10.1542/hpeds.2021-006415
Hospital Pediatrics; Susnerwala S, Joshi A et. al.

Jun 9th, 2022 - Neonatal seizures are one of the most challenging problems for experts across the globe. Although there is no consensus on the "ideal" treatment of neonatal seizures, phenobarbitone has been the drug of choice for decades. Unfortunately, although ...

Background suppression of electrical activity is a potential biomarker of subsequent br...
https://doi.org/10.1152/jn.00024.2022
Journal of Neurophysiology; Zayachkivsky A, Lehmkuhle MJ et. al.

Jun 9th, 2022 - Electrographic seizures and abnormal background activity in the neonatal electroencephalogram (EEG) may differentiate between harmful versus benign brain insults. Using two animal models of neonatal seizures, electrical activity was recorded in fr...

Maternal Serotonergic Antidepressant Use in Pregnancy and Risk of Seizures in Children.
https://doi.org/10.1212/WNL.0000000000200516
Neurology Wiggs KK, Sujan AC et. al.

May 12th, 2022 - To evaluate whether children born to women who use serotonergic antidepressants during pregnancy have higher risk of neonatal seizures and epilepsy. We used Swedish register-based data to examine associations between maternal-reported use of selec...

Clarifications regarding bumetanide for neonatal seizures.
https://doi.org/10.1111/epi.17278
Epilepsia Staley KJ

May 8th, 2022 - A recent Phase II randomized, controlled trial of bumetanide as an adjunctive treatment for neonatal seizures showed a robust efficacy signal and no evidence of toxicity. Concerns regarding bumetanide as an adjunctive anticonvulsant are addressed ...

Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel.
https://doi.org/10.1111/epi.17279
Epilepsia Kaila K, Löscher W

May 8th, 2022 - In his editorial, Kevin Staley criticizes our recent work demonstrating the lack of effect of bumetanide in a novel model of neonatal seizures. The main points in our response are that (1) our work is on an asphyxia model, not one on "hypercarbia ...

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Guidelines  1 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

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Clinicaltrials.gov  26 results

Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
https://clinicaltrials.gov/ct2/show/NCT05361070

May 4th, 2022 - Neonatal seizures due to brain injury (acute provoked seizures) are associated with high risk of post-neonatal epilepsy. Although clinical risk factors can help predict which children are at highest risk for epilepsy, little is known about how gen...

Remote EEG Device for Identification of Risk for Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT05239585

Apr 27th, 2022 - Our goals are to evaluate the effectiveness of the Epilog device in identification of neonates who are at risk for seizures and need formal EEG monitoring or cooling. The current process for these patients would be transfer from Rochester Methodis...

AI-assisted cEEG Diagnosis of Neonatal Seizures in Neonatal Intensive Care Unit
https://clinicaltrials.gov/ct2/show/NCT04991779

Apr 1st, 2022 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The incidence of neonatal seizures is variable based on gestational age. The etiology of seizures...

The Effect of AI-assisted cEEG Diagnosis on the Administration of Antiseizure Medication in Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT05036395

Apr 1st, 2022 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The promoted treatment of seizures can limit the secondary injury to the brain and positively aff...

Neonatal Seizures in NICU of Assuit University Children's Hospital
https://clinicaltrials.gov/ct2/show/NCT05257889

Feb 25th, 2022 - An Overview on neonatal seizures in neonatal intensive care unit of Assuit University Children's hospital , a cross sectional study. The aim of this study is to evaluate the clinical seizures during the neonatal period and its prevalence

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News  38 results

Stopping Seizure Meds Before Hospital Discharge Appears Safe in Most Newborns
https://www.medscape.com/viewarticle/952198

Jun 2nd, 2021 - NEW YORK (Reuters Health) - For most newborns with acute symptomatic seizures, doctors can safely stop antiseizure medications before hospital discharge, without worse neurodevelopmental outcomes or increased risk of epilepsy, a new study suggests...

Phenobarbital for NOWS Tied to Shorter Morphine Duration, Briefer Hospital Stay
https://www.medscape.com/viewarticle/946573

Mar 1st, 2021 - (Reuters Health) - Infants with neonatal opioid withdrawal syndrome (NOWS) may have shorter hospital stays and spend less time on morphine when they receive phenobarbital as secondary therapy, a U.S. study suggests. Researchers examined data on 56...

Halting Antiseizure Medication Poses No Harm in Infants
https://www.medscape.com/viewarticle/939956

Oct 28th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that...

Study supports halting antiseizure medications after neonatal seizures
https://www.mdedge.com/neurology/article/230768/epilepsy-seizures/study-supports-halting-antiseizure-medications-after
Richard Mark Kirkner

Oct 27th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that.

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