ALLMedicine™ Neurofibromatosis Center
Research & Reviews 2,816 results
https://doi.org/10.1148/rg.210235
Radiographics : a Review Publication of the Radiological ... Wang MX, Dillman JR et. al.
Jun 25th, 2022 - Neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2) are autosomal dominant inherited neurocutaneous disorders or phakomatoses secondary to mutations in the NF1 and NF2 tumor suppressor genes, respectively. Although they share a commo...
https://doi.org/10.1111/pde.15044
Pediatric Dermatology; Blegen K, Ortiz-Romero SE et. al.
Jun 25th, 2022 - Elephantiasis neuromatosa (EN) is a rare and extreme form of plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). EN is often associated with significant morbidity and remains difficult to treat. We present a case of an 11-year-...
https://clinicaltrials.gov/ct2/show/NCT04879160
Jun 24th, 2022 - Background: Up to 50% of subjects with Neurofibromatosis Type 1 (NF1) will develop histologically benign plexiform neurofibromas (PN). One of the most common morbidities associated with PN is a disfigurement that has the potential to pose formidab...
https://clinicaltrials.gov/ct2/show/NCT02211768
Jun 24th, 2022 - Background: NF1 is an autosomal dominant genetic disorder characterized by distinct features including the development of benign plexiform neurofibromas (PN) and malignant peripheral nerve sheath tumors (MPNST) tumors of the nervous system. Develo...
https://clinicaltrials.gov/ct2/show/NCT04888936
Jun 24th, 2022 - Study Description:
Guidelines 8 results
https://doi.org/10.1038/gim.2018.28
Genetics in Medicine : Official Journal of the American C... Stewart DR, Korf BR et. al.
Jul 15th, 2018 - This practice resource is designed primarily as an educational resource for medical geneticists and other clinicians to help them provide quality medical services. Adherence to this practice resource is completely voluntary and does not necessaril...
https://doi.org/10.1093/neuros/nyx515
Neurosurgery Germano IM, Sheehan J et. al.
Jan 9th, 2018 - What are the indications for stereotactic radiosurgery (SRS) treatment vs observation for patients with intracanalicular vestibular schwannomas without evidence of radiographic progression? Level 3: If tinnitus is not observed at presentation, it ...
https://doi.org/10.1093/neuros/nyx512
Neurosurgery Hadjipanayis CG, Carlson ML et. al.
Jan 9th, 2018 - What surgical approaches for vestibular schwannomas (VS) are best for complete resection and facial nerve (FN) preservation when serviceable hearing is present? There is insufficient evidence to support the superiority of either the middle fossa (...
https://doi.org/10.1093/neuros/nyx516
Neurosurgery Van Gompel JJ, Agazzi S et. al.
Jan 9th, 2018 - Adults with histologically proven or suspected vestibular schwannomas with neurofibromatosis type 2 (NF2). What is the role of bevacizumab in the treatment of patients with vestibular schwannomas? Level 3: It is recommended that bevacizumab be adm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578356
Neurology Walsh KS, Janusz J et. al.
Aug 17th, 2016 - Neurofibromatosis type 1 (NF1) is associated with neurocognitive deficits that can impact everyday functioning of children, adolescents, and adults with this disease. However, there is little agreement regarding measures to use as cognitive endpoi...
Drugs 2 results see all →
Clinicaltrials.gov 188 results
https://clinicaltrials.gov/ct2/show/NCT01702922
Jun 24th, 2022 - Background: Parents face numerous stressors when their child is diagnosed with cancer or NF1, each of which can strain a marriage/partnership. Marital/partner relationship dynamics are often not assessed or addressed when providing health care for...
https://clinicaltrials.gov/ct2/show/NCT04488263
Jun 24th, 2022 - Background: Neuroendocrine neoplasm (NENs) are divided into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). These are rare malignancies occurring for example in the gastrointestinal tract, islets of the pancreas, lung, adrenal m...
https://clinicaltrials.gov/ct2/show/NCT03739827
Jun 24th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...
https://clinicaltrials.gov/ct2/show/NCT00314119
Jun 24th, 2022 - This protocol results from a funded 2005 Bench-to-Bedside Award and explores the genetic basis of disease severity in neurofibromatosis type 1 (NF1) and the evaluation of three methods to measure disease progression of dermal neurofibromas. NF1 is...
https://clinicaltrials.gov/ct2/show/NCT03531814
Jun 24th, 2022 - Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects approximately 1 in 3,500 individuals and is associated with a broad variety of symptoms and physical findings. Plexiform neurofibromas (PN) are histologically benign tum...
News 93 results
https://www.onclive.com/view/investigators-navigate-the-complicated-treatment-landscape-of-chemotherapy-induced-neutropenia
Jan 19th, 2022 - Advances in the treatment of solid tumors and hematologic malignancies have resulted in the development of thera-peutic regimens that can be administered at various points in a patient’s care. However, as patients’ disease progresses, adverse effe...
https://www.medscape.com/viewarticle/963975
Dec 3rd, 2021 - Guidelines for the diagnosis, treatment, and follow-up of gastrointestinal stromal tumors (GISTs) were published in September 2021 by the European Society for Medical Oncology (ESMO), European Reference Network for Rare Adult Solid Cancers (EURACA...
https://www.mdedge.com/dermatology/article/248079/pediatrics/evaluations-novel-approaches-treating-nf-1-tumors-are-underway
Doug Brunk
Oct 29th, 2021 - In the clinical experience of R. Rox Anderson, MD, currently available treatment options for benign tumors caused by neurofibromatosis type 1 (NF-1) are not acceptable.
http://www.mdedge.com/dermatology/article/247327/dermatopathology/soft-nodule-forearm
Syeda F. Absar, MD, MPH, Tammie C. Ferringer, MD
Oct 13th, 2021 - The Diagnosis: Schwannoma Schwannoma, also known as neurilemmoma, is a benign encapsulated neoplasm of the peripheral nerve sheath that presents as a subcutaneous nodule. 1 It also may present in the retroperitoneum, mediastinum, and viscera (eg, g.
https://www.mdedge.com/dermatology/article/247327/dermatopathology/soft-nodule-forearm
Syeda F. Absar, MD, MPH, Tammie C. Ferringer, MD
Oct 13th, 2021 - The Diagnosis: Schwannoma Schwannoma, also known as neurilemmoma, is a benign encapsulated neoplasm of the peripheral nerve sheath that presents as a subcutaneous nodule. 1 It also may present in the retroperitoneum, mediastinum, and viscera (eg, g.