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About 594 results
Lumbar spinal stenosis is a highly genetic condition partly mediated by disc degeneration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308556
Arthritis & Rheumatology (Hoboken, N.J.); Battié MC, Ortega-Alonso A et. al.

Aug 26th, 2014 - Objective. Lumbar spinal stenosis is one of the most commonly diagnosed spinal disorders in older adults. Although the pathophysiology of the clinical syndrome is not well understood, a narrow central canal or intervertebral foramen is an essential or defining feature. The aim of the present study was to estimate the magnitude of genetic versus environmental influences on central lumbar spinal ...

Osteoid osteoma of the mobile spine: surgical outcomes in 81 patients.
https://doi.org/10.1097/BRS.0b013e3181ffeb5e
Spine Gasbarrini A, Cappuccio M et. al.

Feb 9th, 2011 - A restrospective review of 81 cases of osteoid osteoma of the mobile spine submitted to surgical treatment. Analyze pro and contras of different techniques (conventional and minimally invasive) for the treatment of osteoid osteoma. Intralesional excision has been considered the standard treatment for spinal osteoid osteoma. The high success rate of minimally invasive surgery in the treatment of...

Correlation of higher preoperative American Society of Anesthesiology grade and increas...
https://doi.org/10.3171/2010.12.SPINE10486
Journal of Neurosurgery. Spine; Fu KM, Smith JS et. al.

Feb 7th, 2011 - Patients with varied medical comorbidities often present with spinal pathology for which operative intervention is potentially indicated, but few studies have examined risk stratification in determining morbidity and mortality rates associated with the operative treatment of spinal disorders. This study provides an analysis of morbidity and mortality data associated with 22,857 cases reported i...

The impact of diabetes on the outcomes of surgical and nonsurgical treatment of patient...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005359
Spine Freedman MK, Hilibrand AS et. al.

Jan 28th, 2011 - A secondary analysis comparing diabetic patients with nondiabetic patients enrolled in the Spine Patient Outcomes Research Trial (SPORT). To compare surgical outcomes and complications between diabetic and nondiabetic spine patients. Patients with diabetes are predisposed to comorbidities that may confound the diagnosis and treatment of patients with spinal disorders. Baseline characteristics a...

Spinal fractures in patients with ankylosing spinal disorders: a systematic review of t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899332
European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society; Westerveld LA, Verlaan JJ et. al.

Sep 15th, 2008 - The ankylosed spine is prone to fracture after minor trauma due to its changed biomechanical properties. Although many case reports and small series have been published on patients with ankylosing spondylitis (AS) suffering spine fractures, solid data on clinical outcome are rare. In advanced diffuse idiopathic skeletal hyperostosis (DISH), ossification of spinal ligaments also leads to ankylos...

The pivotal role for the multidisciplinary approach at all phases and at all levels in ...
https://doi.org/10.23736/S1973-9087.19.05984-7
European Journal of Physical and Rehabilitation Medicine; Depreitere B, Jonckheer P et. al.

Sep 26th, 2019 - High level evidence on management of spinal disorders is scarce, which results in guidelines being of limited practical use for practitioners. Care pathways are complex interventions intended for the mutual decision making of organization of care processes for a well-defined group of patient. The goal of this project was to design a pathway for the management of low back pain and radicular pain...

Risk Factors for Symptomatic Contralateral Foraminal Stenosis After Unilateral Transfor...
https://doi.org/10.1016/j.wneu.2019.09.048
World Neurosurgery; Hwang SH, Park SW et. al.

Sep 18th, 2019 - The most common cause of contralateral symptoms after unilateral transforaminal lumbar interbody fusion (TLIF) is contralateral foraminal stenosis (FS). This retrospective cohort study aimed to investigate the cause of and risk factors for contralateral FS after unilateral TLIF with a single cage. Patients with degenerative lumbar spinal disorders who underwent unilateral TLIF at L4-5 were divi...

Johann Peter Frank (1745-1821) and the Pathogenesis of Back Pain.
https://doi.org/10.1097/BRS.0000000000003074
Spine Riva MA, Anghilieri FM et. al.

Sep 15th, 2019 - : Johann Peter Frank (1745-1821) is generally known as one of the founders of the modern Hygiene and Public Health. It is less known his contribution in investigating the pathogenesis of spinal disorders. In his "De Vertebralis Columnae in Morbis Dignitate" (1791), Frank first proposed to use the Latin term "rhachialgia" (back pain) to indicate all the painful states of spine. He focused on the...

Evaluation and management of paediatric and adolescent back pain: Epidemiology, present...
https://doi.org/10.3233/BMR-170987
Journal of Back and Musculoskeletal Rehabilitation; Roberts SB, Calligeros K et. al.

Sep 5th, 2019 - This narrative review will summarise a clinical approach to the investigation of back pain in children and adolescent patients, including a discussion of the epidemiology, presentation, investigation and clinical management of back pain in children and adolescents. This will assist the prompt and accurate diagnosis of spinal disorders that require significant medical intervention. Existing evid...

Less invasive spinal deformity surgery: the impact of the learning curve at tertiary sp...
https://doi.org/10.3171/2019.6.SPINE19531
Journal of Neurosurgery. Spine; Wang MY, Tran S et. al.

Aug 23rd, 2019 - The past decade has seen major advances in techniques for treating more complex spinal disorders using minimally invasive surgery (MIS). While appealing from the standpoint of patient perioperative outcomes, a major impediment to adoption has been the significant learning curve in utilizing MIS techniques. Data were retrospectively analyzed from a multicenter series of adult spinal deformity su...

Anatomical Evaluation of the Sacral Hiatus Using Ultrasound Imaging: Factors That Inhib...
https://doi.org/10.1111/papr.12826
Pain Practice : the Official Journal of World Institute of Pain; Nakahashi M, Uei H et. al.

Aug 3rd, 2019 - Caudal epidural blocks often fail due to the difficulty of appropriate needle insertion. This study aimed to evaluate the anatomy of the sacral hiatus using ultrasound imaging. This was a retrospective study involving 76 patients with spinal disorders. The following factors were analyzed to see if they affected the palpability of the sacral hiatus: sex, body mass index (BMI), and the morphology...

Lumbar spine surgery across 15 years: trends, complications and reoperations in a longi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688683
BMJ Open; Grotle M, Småstuen MC et. al.

Aug 3rd, 2019 - Studies from different Western countries have reported a rapid increase in spinal surgery rates, an increase that exceeds by far the growing incidence rates of spinal disorders in the general population. There are few studies covering all lumbar spine surgery and no previous studies from Norway. The purpose of this study was to investigate trends in all lumbar spine surgery in Norway over 15 ye...

Open versus minimally invasive TLIF: literature review and meta-analysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647286
Journal of Orthopaedic Surgery and Research; Hammad A, Wirries A et. al.

Jul 24th, 2019 - This study is a comparative, literature review. The aim of this study is to provide a comparative analysis of open vs. minimally invasive TLIF using a literature review and a meta-analysis. Lumbar interbody fusion is a well-established surgical procedure for treating several spinal disorders. Transforaminal lumbar interbody fusion (TLIF) was initially introduced in the early 1980s. To reduce ap...

Diffusion tensor imaging reveals changes in microstructural integrity along compressed ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562326
NeuroImage. Clinical; Hughes SW, Hellyer PJ et. al.

Jun 14th, 2019 - Age-related degenerative changes in the lumbar spine frequently result in nerve root compression causing severe pain and disability. Given the increasing incidence of lumbar spinal disorders in the aging population and the discrepancies between the use of current diagnostic imaging tools and clinical symptoms, novel methods of nerve root assessment are needed. We investigated elderly patients w...

Hip or spine surgery first?: a survey of treatment order for patients with concurrent d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568023
The Bone & Joint Journal; Liu N, Goodman SB et. al.

May 30th, 2019 - Patients may present with concurrent symptomatic osteoarthritis (OA) of the hip and degenerative disorders of the lumbar spine, with surgical treatment being indicated for both. Whether arthroplasty of the hip or spinal surgery should be performed first remains uncertain. Clinical scenarios were devised for a survey asking the preferred order of surgery and the rationale for this decision for f...

Degenerative Disc Disease: What is in a Name?
https://doi.org/10.1097/BRS.0000000000003103
Spine Battié MC, Joshi AB et. al.

May 28th, 2019 - A systematic search and review OBJECTIVE.: The aim of this study was to investigate the term, degenerative disc disease, to elucidate its current usage and inform clinical, research, and policy recommendations. Degenerative disc disease has long been a dominant concept in common, painful spinal disorders. Yet, despite its pervasiveness and important clinical consequences and controversies, ther...

Direct healthcare costs of spinal disorders in Brazil.
https://doi.org/10.1007/s00038-019-01211-6
International Journal of Public Health; Carregaro RL, da Silva EN et. al.

May 16th, 2019 - To estimate the direct healthcare costs of spinal disorders in Brazil over 2016. This is a prevalence-based cost-of-illness study with a top-down approach from the perspective of the public healthcare system. All international Classification of Diseases codes related to spinal disorders were included. The following costs were obtained: (1) hospitalization; medical professional service costs; in...

Development of a Biconcave Mobile-Bearing Lumbar Total Disc Arthroplasty Concept Using ...
https://doi.org/10.1002/jor.24315
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society; Zhou C, Willing R

Apr 30th, 2019 - Total disc arthroplasty (TDA) is a motion-preserving surgical treatment for spinal disorders. However, adverse surgical outcomes, such as abnormal kinematics, facet joint (FJ) overloading, and polyethylene (PE) failures, have limited wide application of lumbar TDAs. The objectives of this computational study were to elucidate how implant design and FJ articulation both influence metal-on-polyet...

Decreased catalase expression is associated with ligamentum flavum hypertrophy due to l...
https://doi.org/10.1097/MD.0000000000015192
Medicine Yücetaş ŞC, Çakir T

Apr 15th, 2019 - This is an immunohistologic study of gene expression between patients and controls.This study aims to evaluate expression of the catalase gene in hypertrophied ligamentum flavum (LF) specimens obtained from patients with lumbar spinal canal stenosis (LSCS).LSCS is one of the most common spinal disorders. It is well known that LF hypertrophy plays an important role in the onset of LSCS. Although...

The effectiveness of high intensity laser therapy in the management of spinal disorders...
https://doi.org/10.3233/BMR-181341
Journal of Back and Musculoskeletal Rehabilitation; Alayat MSM, Alshehri MA et. al.

Mar 20th, 2019 - Spinal disorders are common health problems which include wide categories of diseases that affect the spinal soft tissues, joints and bone. The aim of this systematic review was to evaluate the effectiveness of high intensity laser therapy (HILT) on pain and function in patients with spinal disorders. Six databases were searched up to the end of February 2018 including PubMed, MEDLINE, the Coch...