×
About 690 results

ALLMedicine™ Hemangioblastoma Center

Research & Reviews  260 results

Presentation, imaging, patterns of care, growth, and outcome in sporadic and von Hippel...
https://doi.org/10.1007/s11060-022-04021-8
Journal of Neuro-oncology; Takami H, Graffeo CS et. al.

Jul 29th, 2022 - Hemangioblastoma is a relatively rare neoplasm occurring mostly in the cerebellum that may arise sporadically or in the context of von Hippel-Lindau (VHL) syndrome. Presentation, imaging, natural history, surgical patterns of care, and outcomes ar...

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
https://clinicaltrials.gov/ct2/show/NCT04074135

Jul 19th, 2022 - Background: Patients with the von Hippel-Lindau (VHL) familial cancer syndrome demonstrate manifestations in a variety of organs, including the pancreas. Pancreatic manifestations can range from benign cysts and micro cystic adenomas to neuroendoc...

First clinical experience with belzutifan in von Hippel-Lindau disease associated CNS h...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280404
CNS Oncology; Dhawan A, Peereboom DM et. al.

Jul 13th, 2022 - We present two cases of von Hippel-Lindau (VHL) disease-associated hemangioblastomas in the CNS treated with the newly approved HIF-2α inhibitor, belzutifan. The first case is a 31-year-old female with confirmed pathogenic germline VHL mutation wh...

Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
https://clinicaltrials.gov/ct2/show/NCT04458935

Jul 13th, 2022 - Study Description: This study is a retrospective review of medical records in the NIH eye clinic. To our knowledge, there has been no report in the current era dedicated to a description of trans-scleral cryotherapy for retinal hemangioblastomas d...

von Hippel-Lindau Disease
https://emedicine.medscape.com/article/1219430-overview

Jul 12th, 2022 - Overview von Hippel-Lindau (VHL) disease, or von Hippel-Lindau syndrome, is a rare genetic disorder characterized by visceral cysts and benign tumors in multiple organ systems that have subsequent potential for malignant change. [1] Clinical hallm...

see more →

Clinicaltrials.gov  10 results

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
https://clinicaltrials.gov/ct2/show/NCT04074135

Jul 19th, 2022 - Background: Patients with the von Hippel-Lindau (VHL) familial cancer syndrome demonstrate manifestations in a variety of organs, including the pancreas. Pancreatic manifestations can range from benign cysts and micro cystic adenomas to neuroendoc...

Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
https://clinicaltrials.gov/ct2/show/NCT04458935

Jul 13th, 2022 - Study Description: This study is a retrospective review of medical records in the NIH eye clinic. To our knowledge, there has been no report in the current era dedicated to a description of trans-scleral cryotherapy for retinal hemangioblastomas d...

Propranolol and Von Hippel-Lindau Disease
https://clinicaltrials.gov/ct2/show/NCT05424016

Jun 21st, 2022 - 'Von Hippel-Lindau disease (VHL) is a familial syndrome, autosomal dominant, of predisposition to cancer, associating malignant tumors (renal carcinomas, neuroendocrine tumors of the pancreas), or benign tumors (retinal hemangioblastomas (HB), cer...

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas
https://clinicaltrials.gov/ct2/show/NCT01125046

Jan 22nd, 2021 - PRIMARY OBJECTIVES: I. To determine the efficacy of bevacizumab in patients with recurrent or progressive benign and atypical/malignant meningiomas, despite prior therapy, as measured by six-month progression-free survival. SECONDARY OBJECTIVES: I...

non_invasive_aICP_Tumor
https://clinicaltrials.gov/ct2/show/NCT03641443

Feb 26th, 2020 - Primary brain tumors in adults are less common than metastatic tumors. The most frequent are glioblastoma multiforme, metastases, anaplastic astrocytoma, meningioma, pituitary tumors and vestibular schwannoma. 70% of the tumors in adults are supra...

see more →

News  6 results

FDA Grants Priority Review to Belzutifan for VHL Disease–Associated RCC
https://www.onclive.com/view/fda-grants-priority-review-to-belzutifan-for-vhl-disease-associated-rcc

Mar 16th, 2021 - The FDA has granted priority review to the new drug application for the HIF-2α inhibitor belzutifan (MK-6482) for the potential treatment of patients with von Hippel-Lindau (VHL)–associated renal cell carcinoma (RCC) that does not require immediat...

Nichols on Navigating the Nuances of von Hippel-Lindau Disease
https://www.onclive.com/view/nichols-on-navigating-the-nuances-of-von-hippel-lindau-disease

Mar 1st, 2021 - Welcome to OncLive® On Air! I’m your host today, [Gina Mauro]. OncLive On Air is a podcast from OncLive, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and prin...

When to Consider Referral to a Genetic Counselor for Lesser Known Cancer Syndromes
https://www.onclive.com/view/when-to-consider-referral-to-a-genetic-counselor-for-lesser-known-cancer-syndromes

Dec 5th, 2020 - Abstract This article reviews two newly described cancer syndromes: DICER1 and BAP1 tumor predisposition syndrome, and four uncommon syndromes: Familial Atypical Multiple Mole Melanoma (FAMMM) syndrome, Hereditary Leiomyomatosis and Renal Cell Ca...

Durable efficacy with MK-6482 in VHL-associated RCC
https://www.mdedge.com/hematology-oncology/article/229866/renal-cell-carcinoma/durable-efficacy-mk-6482-vhl-associated-rcc
Walter Alexander

Oct 12th, 2020 - The investigational agent MK-6482 demonstrated durable efficacy and a favorable safety profile in a phase 2 trial of patients with Von Hippel-Lindau (VHL) disease-associated renal cell carcinoma (RCC) and nonrenal lesions, according to a presentat.

What is your diagnosis? - July 2019
https://www.mdedge.com/gihepnews/article/203798/what-your-diagnosis-july-2019?channel=27662
Wai See Ma, MD, Hadi Moattar, MD, MBChB, PhD

Jun 28th, 2019 - The diagnosis von Hippel-Lindau disease The diagnosis is von Hippel-Lindau disease (VHL). Subsequent brain and renal magnetic resonance imaging showed features suggestive of a 5-mm right cerebellar hemangioblastoma and right renal cell carcinoma (.

see more →