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About 100 results

ALLMedicine™ Pineal Tumors Center

Research & Reviews  38 results

Staged operations for a hypervascular mixed germ cell tumor with growing teratoma syndr...
https://doi.org/10.1007/s00381-021-05393-4 10.1016/j.clon.2018.01.009 10.1159/000358806 10.1159/000210053 10.1007/s11060-010-0238-1 10.4103/2152-7806.129430 10.1023/A:1012766902431 10.1007/s11060-016-2138-5 10.3171/2012.1.JNS111402 10.15264/cpho.2016.23.1.17 10.3171/2010.10.PEDS0976 10.1002/1097-0142(19821015)50:8<1629::AID-CNCR2820500828>3.0.CO;2-1 10.1007/s11060-020-03486-9 10.1007/s10014-017-0297-5 10.1093/ons/opy092
Child's Nervous System : ChNS : Official Journal of the I... Jung TY, Baek HJ et. al.

Nov 11th, 2021 - A mixed germ cell tumor with a teratoma component can become enlarged following chemotherapy, and such an event is diagnosed as growing teratoma syndrome. Removing large, hypervascular tumors including a tumor encased by developed vasculatures fro...

Quantifying the Risk and Dosimetric Variables of Symptomatic Brainstem Injury After Pro...
https://doi.org/10.1016/j.ijrobp.2021.07.198
International Journal of Radiation Oncology, Biology, Phy... Upadhyay R, Grosshans DR et. al.

Oct 28th, 2021 - Brainstem toxicity after radiation is a devastating complication and a particular concern with proton radiation (RT), given the biological differences and range uncertainties at the distal edge of proton beam. Data from St. Jude's found a 3.7% ris...

Molecular classification of a complex structural rearrangement of the RB1 locus in an i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025529
Acta Neuropathologica Communications; Schieffer KM, Feldman AZ et. al.

Apr 9th, 2021 - Retinoblastoma is a childhood cancer of the retina involving germline or somatic alterations of the RB Transcriptional Corepressor 1 gene, RB1. Rare cases of sellar-suprasellar region retinoblastoma without evidence of ocular or pineal tumors have...

Central Nervous System Germinoma
http://emedicine.medscape.com/article/281714-overview

Mar 25th, 2021 - Practice Essentials Germ cell tumors (GCTs) in the central nervous system (CNS) typically affect children and young adults, predominantly occurring in the first and second decade of life [1] ; the peak incidence is from 10-19 years of age. [2, 3] ...

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes co...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275775
Acta Neuropathologica; Pfaff E, Aichmüller C et. al.

Nov 27th, 2019 - Tumors of the pineal region comprise several different entities with distinct clinical and histopathological features. Whereas some entities predominantly affect adults, pineoblastoma (PB) constitutes a highly aggressive malignancy of childhood wi...

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Clinicaltrials.gov  2 results

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT01182883

Jul 2nd, 2017 - Background IMC-A12 is a fully recombinant IgG1monoclonal antibody to the insulin-like growth factor receptor (IGFR). It acts as an antagonist of IGF-1 and IGF-2 ligand binding and blocks ligand binding to IGF-1R and inhibits downstream signaling o...

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas
https://clinicaltrials.gov/ct2/show/NCT01132911

Jul 2nd, 2017 - Background: -The combination of vorinostat and bortezomib has been shown to be synergistic in vitro in a variety of malignancies, including hepatoma, multiple myeloma, leukemia, lymphoma, and gastrointestinal cancer. Currently several phase 2 adul...

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