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About 232,850 results
Efficacy of Laparoscopic Nissen Fundoplication vs Transoral Incisionless Fundoplication...
https://doi.org/10.1053/j.gastro.2017.12.021
Gastroenterology Richter JE, Kumar A et. al.

Jan 6th, 2018 - The effects of transoral incisionless fundoplication (TIF) and laparoscopic Nissen fundoplication (LNF) have been compared with those of proton pump inhibitors (PPIs) or a sham procedure in patients with gastroesophageal reflux disease (GERD), but there has been no direct comparison of TIF vs LNF. We performed a systematic review and network meta-analysis of randomized controlled trials to comp...

Update on the Management of Constipation
https://jamanetwork.com/journals/jama/article-abstract/2754106
JAMA Wald A

Nov 16th, 2019 - Chronic constipation is very common. The most recent estimate of clinician visits attributable to constipation were from 2001 to 2004 and reported more than 8 million clinician visits in the United States, with most occurring in adult primary care settings (33%) followed by pediatric (21%) and gastroenterologist (14%) offices.1 These encounters result in large expenditures for nonprescription l...

Chronic Constipation: New Insights, Better Outcomes?
https://www.ncbi.nlm.nih.gov/pubmed/31609241
Lancet Gastroenterology Hepatology; Schiller LR

Oct 31st, 2019 - Constipation is a symptom that affects around 11-20% of the adult population yearly. Most physicians consider infrequency of defecation as a hallmark of constipation. However, most patients view excessive straining as the biggest component of constipation and only a minority of patients with constipation have infrequent bowel movements.

A Comparison of the Efficacy of Enema Solutions in Pediatric Emergency Department Patients
https://www.ncbi.nlm.nih.gov/pubmed/31594739
Journal of Emergency Medicine; Anderson J, et al

Oct 4th, 2019 - Children presenting to pediatric emergency departments (EDs) are frequently given enemas for relief of constipation symptoms; there is very little literature guiding solution selection.

Opioid Use Disorder: Medical Treatment Options
https://www.aafp.org/afp/2019/1001/p416.html
American Family Physician; Coffa, D. et. al.

Sep 30th, 2019 - Opioid use disorder is highly prevalent and can be fatal. At least 2.1 million Americans 12 years and older had opioid use disorder in 2016, and approximately 47,000 Americans died from opioid overdoses in 2017. Opioid use disorder is a chronic relapsing condition, the treatment of which falls within the scope of practice of family physicians. With appropriate medication-assisted treatment, pat...

Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus Infection in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2018 Clinical Practice Guideline
https://annals.org/aim/fullarticle/2751913/prevention-diagnosis-evaluation-treatment-hepatitis-c-virus-infection-chronic-kidney

Sep 23rd, 2019 - Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is an extensive update of KDIGO's 2008 guideline on HCV infection in CKD. This update reflects the major advances since the introduction of direct-acting antivirals (DAAs...

Alarming number of heart infections tied to opioid epidemic
https://newsroom.heart.org/news/alarming-number-of-heart-infections-tied-to-opioid-epidemic

Sep 17th, 2019 - An alarming number of people nationwide are developing infections of either the heart’s inner lining or valves, known as infective endocarditis, in large part, due to the current opioid epidemic. This new trend predominantly affects young, white, poor men who also have higher rates of HIV, hepatitis C and alcohol abuse, according to new research published in the Journal of the American Heart As...

Efficacy of Drugs in Chronic Idiopathic Constipation: a Systematic Review & Network Meta-Analysis
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(19)30246-8/fulltext
The Lancet Gastroenterology & Hepatology; Luthra P, et al

Aug 28th, 2019 - There are several drugs available for the treatment of chronic idiopathic constipation, but their relative efficacy is unclear because there have been no head-to-head randomised controlled trials. We did a network meta-analysis to compare the efficacy of these therapies in patients with chronic idiopathic constipation.

FDA warns about rare occurrence of serious liver injury with use of hepatitis C medicines Mavyret, Zepatier, and Vosevi in some patients with advanced liver disease
https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-about-rare-occurrence-serious-liver-injury-use-hepatitis-c-medicines-mavyret-zepatier-and

Aug 27th, 2019 - The Food and Drug Administration (FDA) has received reports that the use of Mavyret, Zepatier, or Vosevi to treat chronic hepatitis C in patients with moderate to severe liver impairment has resulted in rare cases of worsening liver function or liver failure. All these medicines contain a hepatitis C virus (HCV) protease inhibitor and are not indicated for use in patients with moderate to sever...

Treating Hepatitis C in the Family Medicine Office
https://www.aafp.org/afp/2019/0815/p248.html
American Family Physician;

Aug 14th, 2019 - Patient story about being diagnosed with hepatitis C and successful treatment by family doctor.

Preparing for a colonoscopy
https://www.health.harvard.edu/diseases-and-conditions/preparing-for-a-colonoscopy

Aug 12th, 2019 - If you shudder at the thought of having a colonoscopy to check for hidden colon cancer, chances are it's the "prep" that's stoking your apprehension. It's certainly a major inconvenience: getting ready for the procedure takes much longer — an average of 16 hours, according to one study — than the three hours or so you'll spend at a medical center the day of your colonoscopy. But what's most off...

FDA warns consumers about the dangerous and potentially life threating side effects of Miracle Mineral Solution
https://www.fda.gov/news-events/press-announcements/fda-warns-consumers-about-dangerous-and-potentially-life-threating-side-effects-miracle-mineral

Aug 11th, 2019 - The U.S. Food and Drug Administration is warning consumers not to purchase or drink a product sold online as a medical treatment due to a recent rise in reported health issues. Since 2010, the FDA has warnedExternal Link Disclaimer consumers about the dangers of Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide (CD) Protocol, Water Purification Solution (WPS)...

Adnexal Torsion in Adolescents
https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Adolescent-Health-Care/Adnexal-Torsion-in-Adolescents
Adnexal Torsion in Adolescents

Jul 24th, 2019 - Adnexal torsion is the fifth most common gynecologic emergency. The most common ovarian pathologies found in adolescents with adnexal torsion are benign functional ovarian cysts and benign teratomas. Torsion of malignant ovarian masses in this population is rare. In contrast to adnexal torsion in adults, adnexal torsion in pediatric and adolescent females involves an ovary without an associated...

Screening for Hepatitis B Virus Infection in Pregnant Women US Preventive Services Task Force Reaffirmation Recommendation Statement
https://jamanetwork.com/journals/jama/fullarticle/2738558
JAMA

Jul 22nd, 2019 - Screening for hepatitis B virus (HBV) infection during pregnancy identifies women whose infants are at risk of perinatal transmission. Data from a nationally representative sample showed a prevalence of maternal HBV infection of 85.8 cases per 100 000 deliveries from 1998 to 2011 (0.09% of live-born singleton deliveries in the United States). Although there are guidelines for universal infant H...

Hepatitis B Screening in Pregnant Women A Perspective on the New USPSTF Recommendations
https://jamanetwork.com/journals/jama/fullarticle/2738527
JAMA

Jul 22nd, 2019 - Contemporary clinicians who provide obstetric care acknowledge screening of pregnant women for perinatally transmissible infectious diseases as a routine component of prenatal care,1 although this has not always been the case. For example, prenatal screening for hepatitis B virus (HBV) infection only began to be discussed after rigorous trials conducted in the 1970s and 1980s in high-endemic ar...

AGA Guideline on the Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D)
https://www.gastrojournal.org/article/S0016-5085(19)41083-4/fulltext?referrer=https%3A%2F%2Fwww.jwatch.org%2Fna49679%2F2019%2F08%2F09%2Ftesting-functional-diarrhea-and-diarrhea-predominant

Jul 10th, 2019 - This document presents the official recommendations of the American Gastroenterological Association (AGA) on the Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) in Adults. The guideline was developed by the AGA’s Clinical Practice Guideline Committee and approved by the AGA Governing Board. These Guidelines should expire in 5 years. The ...

HIV and Viral Hepatitis - CDC
https://www.cdc.gov/hiv/pdf/library/factsheets/hiv-viral-hepatitis.pdf

Jun 26th, 2019 - People with HIV infection are affected disproportionally by viral hepatitis. Nearly 75% of people with HIV who report a history of injection drug use also are infected with hepatitis C virus (HCV).

Chronic inflammatory liver diseases and coffee intake
https://journals.lww.com/co-clinicalnutrition/Abstract/publishahead/Chronic_inflammatory_liver_diseases_and_coffee.99131.aspx
Current Opinion in Clinical Nutrition & Metabolic Care; Contaldo, F. et. al.

Jun 17th, 2019 - Purpose of review To review the healthy protective effects of coffee against several metabolic diseases and some types of cancer. In this short review, the possible preventive and/or therapeutic actions of coffee on liver function is focused. Recent findings The protective mechanisms of coffee are various and because of several components with anti-inflammatory and antioxidant properties in ...

What Is the Role of Intravenous and Intraoral Contrast in CT Evaluation of Acute Appendicitis?
https://www.aaem.org/UserFiles/file/Post-CTEvalofAcuteAppendicitis.pdf

Jun 6th, 2019 - Patients presenting to the emergency department (ED) with abdominal pain and concern for appendicitis typically require diagnostic imaging to confirm the diagnosis. Computer tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US) are the imaging modalities that can be used to diagnosis appendicitis. For non-pregnant adult appendicitis, CT of the abdomen and pelvis is commonly...

Assessing Abdominal Pain in Adults: A Rational, Cost-Effective, and Evidence-Based Strategy
https://www.ebmedicine.net/topics.php?paction=showTopic&topic_id=603&ad=digest

May 31st, 2019 - Be wary of early diagnostic closure and misdiagnosis of abdominal pain; there are many abdominal and extra-abdominal mimics of dangerous etiologies. The elderly, the immunocompromised, women of childbearing age, and patients with prior abdominal surgeries are at a higher risk for misdiagnosis. The peritoneum becomes less sensitive with age, and peritonitis can be a late or absent finding. El...