About 111,440 results

ALLMedicine™ Fractures Center

Research & Reviews  38,112 results

Formulation and Characterization of Phytosomes as Drug Delivery System of Formononetin:...
Current Drug Delivery; Agarwal A, Wahajuddin M et. al.

Feb 4th, 2023 - Formononetin (FNT), a methoxy isoflavone, is a potential phytoconstituent utilized for refurbishing fractures in bone tissue. Conceding to its involvement in first-pass metabolism followed by glucuronidation, its absorption efficacy is limited. He...

MiR-181a-5p promotes osteogenesis by targeting BMP3.
Aging Long Z, Dou P et. al.

Feb 4th, 2023 - High-throughput microRNA (miRNA) sequencing of osteoporosis was analyzed from the Gene Expression Omnibus (GEO) database to investigate specific microRNAs that control osteogenesis. MiR-181a-5p was differentially expressed among healthy subjects a...

Treatment of Pathological Fracture of Radius due to Multiple Myeloma with Elastic Intra...
Journal of Long-term Effects of Medical Implants; Ntontis Z, Koutserimpas C et. al.

Feb 4th, 2023 - Pathological fractures of the proximal radius are exceedingly rare. Here, a case of an 81-year-old female diagnosed with multiple myeloma 15 years ago who suffered a pathological fracture of her left proximal radius is presented. Due to the fractu...

Prevalence of osteoporosis and incidence of related fractures in developed economies in...
Osteoporosis International : a Journal Established as Res... Chandran M, Brind'Amour K et. al.

Feb 4th, 2023 - Robust data on osteoporosis in the Asia Pacific region could improve healthcare decision-making. Osteoporosis affects 10-30% of women aged 40 + , and up to 10% of men in 7 developed economies in Asia Pacific. Fractures affect 500-1000 adults aged ...

Common Finger Injuries: Treatment Guidelines for Emergency and Primary Care Providers.
Military Medicine; Hunt TJ, Powlan FJ et. al.

Feb 4th, 2023 - Finger and hand injuries are among the most common musculoskeletal conditions presenting to emergency departments and primary care providers. Many rural and community hospitals may not have immediate access to an orthopedic surgeon on-site. Furthe...

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Guidelines  75 results

ACR Appropriateness Criteria® Osteoporosis and Bone Mineral Density: 2022 Update.
Journal of the American College of Radiology : JACR; , Yu JS et. al.

Nov 28th, 2022 - Osteoporosis constitutes a significant public health risk. An estimated 10.2 million adults in the United States >50 years of age have osteoporosis, a systemic condition that weakens the bones increasing the susceptibility for fractures. Approxima...

AAOS Management of Hip Fractures in Older Adults Evidence-based Clinical Practice Guide...
The Journal of the American Academy of Orthopaedic Surgeons; Switzer JA, O'Connor MI

Oct 7th, 2022 - AAOS Management of Hip Fractures in Older Adults Evidence-based Clinical Practice Guideline.|2022|Switzer JA,O'Connor MI,|surgery,

Vitamin D and Fracture Risk among Adults
The New England Journal of Medicine;

Jul 28th, 2022 - Although supplemental vitamin D is widely recommended for bone health, whether it can help prevent fractures in midlife and older adults is unclear. New research findings are summarized in a short video.

Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults
The New England Journal of Medicine; LeBoff MS, .

Jul 28th, 2022 - Vitamin D supplements are widely recommended for bone health in the general population, but data on whether they prevent fractures have been inconsistent.

Best Practices Guidelines: Spine Injury
American College of Surgeons (ACS)

Mar 31st, 2022 - Fractures of the spinal column represent a small proportion of all fractures from traumatic injury with an incidence ranging from 4 to 23 percent.1,2 However, their impact on the individual and the health care system is significant because of ...

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Drugs  198 results see all →

Clinicaltrials.gov  3,045 results

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

Feb 3rd, 2023 - This is a local, non-interventional, multi-center, single-cohort study using primary data of patients treated with Xofigo for the indication of castration resistant prostate cancer (CRPC) with bone metastases. A total of 300 patients (valid for sa...

Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System

Feb 3rd, 2023 - The aim of this one-year study is to demonstrate Tomo-E's clinical utility for diagnosis of wrist fractures. Tomo-E is a compact and stationary device that utilizes a distributed carbon nanotube (CNT) x-ray source array that will be specially desi...

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy)...

Feb 3rd, 2023 - PRIMARY OBJECTIVES: I. To determine the maximum tolerated dose (MTD) of peposertib (M3814) in combination with radium-223 dichloride or in combination with radium-223 dichloride and avelumab in patients with advanced metastatic castrate-resistant ...

Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study

Feb 3rd, 2023 - Study Description: This is a deep phenotype study of women who are determined to have 45,X mosaicism as a secondary genomic finding following cfDNA sequencing during pregnancy. Objectives: To define and describe a comprehensive phenotype of women ...

Short-Term Outcomes Of Subaxial Cervical Injuries

Feb 3rd, 2023 - Initially, all patients with subaxial cervical spine fractures require immobilization in a rigid cervical orthosis (2). Patients receiving conservative treatment are often prescribed a rigid cervical or cervicothoracic orthosis for 6 to 12 weeks w...

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News  2,887 results

14-year-old boy • aching midsternal pain following a basketball injury • worsening pain with direct pressure and when the patient sneezed • Dx?
MDedge Family Medicine; Catherine Romaine, BS, Alyssa Heinrich, MD et. al.

Jan 30th, 2023 - THE CASE A 14-year-old boy sought care at our clinic for persistent chest pain after being hit in the chest with a teammate’s shoulder during a basketball game 3 weeks earlier. He had aching midsternal chest pain that worsened with direct pressure.

Jardiance Under Review for CKD; Frailty in Obesity; DIY Semaglutide?

Jan 24th, 2023 - The FDA is reviewing a potential new indication for empagliflozin (Jardiance) for risk reduction of kidney disease progression and cardiovascular death in adults with chronic kidney disease (CKD) based on the EMPA-KIDNEY phase III trial, Boehringe...

Carotid Plaque & Hearing Loss; Exercise Intervention for Afib; MitraClip Lock Issue

Jan 24th, 2023 - In the Atherosclerosis Risk in Communities cohort, people with carotid atherosclerosis in mid-life were more likely to have worse hearing decades later. (JAMA Otolaryngology-Head & Neck Surgery) Higher HDL cholesterol corresponded with a higher ri...

Geriatrician advises on use of vitamin D supplementation, lecanemab, and texting for her patients
Mengru Wang, MD, MPH

Jan 20th, 2023 - This article discusses updates in geriatrics from studies published in 2022 to early 2023. The topics covered include vitamin D supplementation and incident fractures, the association of social isolation and dementia, and the release of lecanemab,.

Aspirin Toe-to-Toe With LMWH Injections in Orthopedic Trauma

Jan 18th, 2023 - For patients with a variety of traumatic bone fractures, plain old oral aspirin provided just as good thromboprophylaxis as traditional low-molecular-weight heparin (LMWH) injections in the large PREVENT CLOT randomized trial. Aspirin met noninfer...

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Patient Education  259 results see all →