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About 81,198 results

ALLMedicine™ Rheumatoid Arthritis Center

Research & Reviews  23,107 results

Commentary: Examining Lower Doses and Effectiveness in RA Treatments, July 2022
https://www.mdedge.com/rheumatology/article/255999/rheumatoid-arthritis/commentary-examining-lower-doses-and-effectiveness
Arundathi Jayatilleke, MD

Jul 1st, 2022 - Arundathi Jayatilleke, MD In keeping with other studies suggesting that lower-than-standard doses of rituximab (for example, two 500 mg doses every 6 months) are effective in the treatment of rheumatoid arthritis (RA), Bertsias and colleagues eval.

A MUC5B Gene Polymorphism, rs35705950-T Confers Protective Effects Against COVID-19 Hos...
https://doi.org/10.1164/rccm.202109-2166OC
American Journal of Respiratory and Critical Care Medicine; Verma A, Minnier J et. al.

Jul 1st, 2022 - A common MUC5B gene polymorphism, rs35705950-T, is associated with idiopathic pulmonary fibrosis (IPF), but its role in SARS-CoV-2 infection and disease severity is unclear. To assess whether rs35705950-T confers differential risk for clinical out...

Gout and Pseudogout
https://emedicine.medscape.com/article/329958-overview

Jul 1st, 2022 - Practice Essentials Gout and pseudogout are the 2 most common crystal-induced arthropathies. Gout (see the image below) is caused by monosodium urate monohydrate crystals; pseudogout is caused by calcium pyrophosphate crystals and is more accurate...

Gout and Pseudogout
http://emedicine.medscape.com/article/329958-overview

Jul 1st, 2022 - Practice Essentials Gout and pseudogout are the 2 most common crystal-induced arthropathies. Gout (see the image below) is caused by monosodium urate monohydrate crystals; pseudogout is caused by calcium pyrophosphate crystals and is more accurate...

Toxic effects of pesticides on cellular and humoral immunity: an overview.
https://doi.org/10.1080/08923973.2022.2096466
Immunopharmacology and Immunotoxicology; Vivan Cestonaro L, Dias Macedo SM et. al.

Jul 1st, 2022 - People are exposed to pesticides through food, drinking water, and the environment. These compounds are associated with several disorders, such as inflammatory diseases, rheumatoid arthritis, cancer, and a condition related to metabolic syndrome. ...

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Guidelines  33 results

EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761998
Annals of the Rheumatic Diseases; Nagy G, Roodenrijs NMT et. al.

Aug 20th, 2021 - To develop evidence-based European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid arthritis (D2T RA). An EULAR Task Force was established comprising 34 individuals: 2...

EULAR points to consider for conducting clinical trials and observational studies in in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458095
Annals of the Rheumatic Diseases; Mankia K, Siddle HJ et. al.

Aug 8th, 2021 - Despite growing interest, there is no guidance or consensus on how to conduct clinical trials and observational studies in populations at risk of rheumatoid arthritis (RA). An European League Against Rheumatism (EULAR) task force formulated four r...

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.
https://doi.org/10.1002/acr.24596
Arthritis Care & Research; Fraenkel L, Bathon JM et. al.

Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grad...

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.
https://doi.org/10.1002/art.41752
Arthritis & Rheumatology (Hoboken, N.J.); Fraenkel L, Bathon JM et. al.

Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grad...

Clinical Practice Guideline for Physical Therapist Management of People With Rheumatoid...
https://doi.org/10.1093/ptj/pzab127
Physical Therapy; Peter WF, Swart NM et. al.

May 19th, 2021 - This guideline revises the 2008 Royal Dutch Society for Physical Therapy guideline for physical therapy for patients with rheumatoid arthritis (RA). This revised guideline was developed according to the Appraisal of Guidelines for Research and Eva...

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Drugs  1,933 results see all →

Clinicaltrials.gov  2,827 results

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
https://clinicaltrials.gov/ct2/show/NCT02759731

Jun 24th, 2022 - Background: Chronic graft-versus-host disease (cGVHD) is the leading cause of non-relapse morbidity and mortality in persons after allogeneic hematopoietic stem cell transplantation (SCT). Approximately 50% of patients with cGVHD have disease refr...

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene
https://clinicaltrials.gov/ct2/show/NCT01145196

Jun 24th, 2022 - OBJECTIVE: The objective of this study is to investigate whether there is a correlation between genetic mutations, beginning with an analysis of ABCA4, and Plaquenil -induced retinal toxicity and to describe the phenotype of Plaquenil -induced ret...

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
https://clinicaltrials.gov/ct2/show/NCT02281747

Jun 24th, 2022 - Major orthopedic procedures, including total joint replacement and spine surgeries, are among the most common procedures in the population. Learning about how often these surgeries are performed can give indications of whether the treatment of art...

A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an In...
https://clinicaltrials.gov/ct2/show/NCT04909801

Jun 24th, 2022 - The purpose of this study is to evaluate the superiority in efficacy of abatacept compared with adalimumab, on background methotrexate, in adults with early, seropositive, and shared epitope-positive rheumatoid arthritis and an inadequate methotre...

Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis
https://clinicaltrials.gov/ct2/show/NCT03912428

Jun 24th, 2022 - I. Objective 18-kDa translocator protein (TSPO) and cyclooxygenase-2 (COX-2) are both implicated in the pathophysiology of various inflammatory disorders, suggesting that both may serve as potential biomarkers of inflammation in brain as well as p...

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News  4,515 results

Commentary: Examining Lower Doses and Effectiveness in RA Treatments, July 2022
https://www.mdedge.com/rheumatology/article/255999/rheumatoid-arthritis/commentary-examining-lower-doses-and-effectiveness
Arundathi Jayatilleke, MD

Jul 1st, 2022 - Arundathi Jayatilleke, MD In keeping with other studies suggesting that lower-than-standard doses of rituximab (for example, two 500 mg doses every 6 months) are effective in the treatment of rheumatoid arthritis (RA), Bertsias and colleagues eval.

Commentary: Evaluating New Treatments and Cardiovascular Risk in PsA, July 2022
https://www.mdedge.com/rheumatology/article/255943/psoriatic-arthritis/commentary-evaluating-new-treatments-and
Vinod Chandran, MBBS, MD, DM, PhD

Jun 30th, 2022 - Vinod Chandran, MBBS, MD, DM, PhD Inhibition of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway by JAK inhibitors is efficacious in psoriatic arthritis (PsA). On the basis of the results of the pivotal SELECT-P.

Rheumatoid arthritis increases mortality risk in chronic kidney disease
https://www.mdedge.com/rheumatology/article/255911/rheumatoid-arthritis/rheumatoid-arthritis-increases-mortality-risk

Jun 29th, 2022 - Key clinical point: Patients with both chronic kidney disease (CKD) and rheumatoid arthritis (RA) were at an increased risk for mortality compared with those with CKD alone, with RA having no impact on progressive renal decline. Major finding: Pre.

Real-world study evaluates benefits of treat-to-target therapy for BMD loss in RA
https://www.mdedge.com/rheumatology/article/255910/rheumatoid-arthritis/real-world-study-evaluates-benefits-treat-target

Jun 29th, 2022 - Key clinical point: Loss of bone mineral density (BMD) was lower in patients with rheumatoid arthritis (RA) who achieved remission, indicating an important role of treat-to-target therapy in RA, with female sex being a risk factor and low disease.

Joint-inflammation trajectories differ by SDFR status in ACPA-positive and ACPA-negative RA
https://www.mdedge.com/rheumatology/article/255909/rheumatoid-arthritis/joint-inflammation-trajectories-differ-sdfr-status

Jun 29th, 2022 - Key clinical point: Patients with anticitrullinated peptide antibody (ACPA)-positive and ACPA-negative rheumatoid arthritis (RA) show different magnetic resonance imaging-detected joint inflammation trajectories based on the sustained disease-modi.

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Patient Education  64 results see all →