About 34,703 results

ALLMedicine™ Systemic Lupus Erythematosus Center

Research & Reviews  11,450 results

How toxic is an old friend? A review of the safety of hydroxychloroquine in clinical pr...
Internal Medicine Journal; Fairley JL, Nikpour M et. al.

Aug 16th, 2022 - Hydroxychloroquine (HCQ) and its close relative chloroquine (CQ) were initially used as antimalarial agents but are now widely prescribed in rheumatology, dermatology and immunology for the management of autoimmune diseases. HCQ is considered to h...

Determination of the main causes, outcome, and prognostic factors of patients with rheu...
Clinical Rheumatology; Arjmand M, Shahriarirad R et. al.

Aug 16th, 2022 - Systemic rheumatic diseases (SRD) are a heterogeneous group of diseases that can involve several organ systems and occasionally requires intensive care unit (ICU) admission because of severe systemic disease, life-threatening organ involvement, or...

Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythemat...
Journal of Immunology Research; Zhao Y, Qi Y et. al.

Aug 16th, 2022 - Systemic lupus erythematosus (SLE) has become increasingly common in the clinic and requires complicated evidence of both clinical manifestations and laboratory examinations. Additionally, the assessment and monitoring of lupus disease activity ar...

Extrapolation of Adult Efficacy Data to Pediatric Systemic Lupus Erythematosus.
Journal of Clinical Pharmacology; Balevic SJ, Niu J et. al.

Aug 16th, 2022 - To streamline drug development, the FDA can consider the extrapolation of adult efficacy data to children when the disease and drug effects are sufficiently similar. This study explored whether the relationship between drug exposure and response f...

Neck Pain with Abdominal Distention in a Patient with Systemic Lupus Erythematosus.
Gastroenterology Uda K, Shigehara K et. al.

Aug 15th, 2022 - Neck Pain with Abdominal Distention in a Patient with Systemic Lupus Erythematosus.|2022|Uda K,Shigehara K,Yashiro M,|

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Guidelines  11 results

The significance of the low sex ratios of offspring and of sibs of probands with system...
Early Human Development; James WH, Grech V

Sep 8th, 2019 - There is good evidence that there are significantly low sex ratios (proportions male) in the offspring of patients with some immune diseases e.g. systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There is also strong evidence that ...

2019 update of the EULAR recommendations for the management of systemic lupus erythemat...
Annals of the Rheumatic Diseases; Fanouriakis A, Kostopoulou M et. al.

Mar 31st, 2019 - Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic literature review (01/2007-12/2017), followed by modified Delphi method, to f...

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

The British Society for Rheumatology guideline for the management of systemic lupus ery...
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,immunology,therapy,

The British Society for Rheumatology guideline for the management of systemic lupus ery...
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,therapy,standards,standards,

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Drugs  407 results see all →

Clinicaltrials.gov  728 results

Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus

Aug 12th, 2022 - Study Design: This is a study of the acute effects of glucocorticoids on the immune system of patients with SLE. Participants will undergo baseline blood collection prior to receiving a single intravenous (IV) dose of methylprednisolone sodium suc...

A Study of Guselkumab in Participants With Active Lupus Nephritis

Aug 12th, 2022 - Guselkumab is a monoclonal antibody (mAb) that binds to human interleukin (IL)-23 with high affinity and blocks binding of extracellular IL-23 to cell surface IL-23 receptor, inhibiting IL 23 specific intracellular signaling and subsequent activat...

SAPHNELO Systemic Lupus Erythematosus Japan Post-Marketing Surveillance (PMS)

Aug 12th, 2022 - The objective of the Specific Use Result Study is to collect information on and evaluate the long-term safety and effectiveness of Anifrolumab in patients with systemic lupus erythematosus insufficiently responding to currently available treatment...

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

Aug 12th, 2022 - The purpose of this study is to evaluate long-term safety and tolerability of dapirolizumab pegol treatment.

Study of Systemic Lupus Erythematosus

Aug 12th, 2022 - This research protocol will evaluate subjects with systemic lupus erythematosus (SLE) and their relatives to study the pathogenesis and natural history of the disease and the mechanisms leading to enhanced organ damage. Patients will be evaluated ...

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News  1,273 results

Anti-BDCA2 Antibody Meets Primary Endpoint in Phase 2 Cutaneous Lupus Trial

Aug 4th, 2022 - Treatment with the humanized monoclonal antibody litifilimab improved scores on a validated measure of skin disease activity in an international phase 2 trial of patients with cutaneous lupus erythematosus (CLE). Improvements in Cutaneous Lupus Er...

Calcinosis Cutis Associated With Subcutaneous Glatiramer Acetate
Christina N. Kraus, MD, Sama K. Carley, MD et. al.

Jul 28th, 2022 - To the Editor: Calcinosis cutis is a condition characterized by the deposition of insoluble calcium salts in the skin. Dystrophic calcinosis cutis is the most common type, occurring in previously traumatized skin in the absence of abnormal blood c.

FDA Approves Belimumab for Children With Lupus Nephritis

Jul 28th, 2022 - The US Food and Drug Administration (FDA) has approved belimumab (Benlysta) for treating active lupus nephritis (LN) in children aged 5–17 years. The drug can now be used to treat adult and pediatric patients with systemic lupus erythematosus (SLE...

Approach to Pancytopenia in a Deployed Service Member
Steven J. Gibson, MD, Benjamin Swanson, MD et. al.

Jul 1st, 2022 - Pancytopenia is a condition in which all 3 hematologic cell lines are lower than expected in the blood, often representing either an increase in cellular destruction or decrease in bone marrow production. Destruction often occurs in the setting of.

Azathioprine Discontinuation Linked to Genotype Regardless of Race

Jun 21st, 2022 - NEW YORK (Reuters Health) - Across multiple disease settings, patients with the rs2814778-CC genotype face a higher risk of stopping azathioprine due to hematopoietic toxicity and receiving lower doses of thiopurines, regardless of race, a new stu...

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Patient Education  12 results see all →